Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65562 products of "Quinazoline and Quinoline Derivatives"
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Olanzapine N-Oxide
CAS:<p>Impurity Olanzapine EP Impurity D/ Olanzepine USP Related Compound C<br>Applications A metabolite of Olanzapine (Olanzapine EP Impurity D).<br>References Jacobsen, E., et al.: Acta Pharmacol. Toxacol., 11, 135 (1955), Chakrabarti, J.K., et al.: J. Med. Chem., 23, 878 (1980), Luo, H., et al.: J. Pharm. Sci., 11, 1079 (1992), Moore, N.A., et al.: Curr. Opin. Invest. Drugs, 2, 281 (1993),<br></p>Formula:C17H20N4OSColor and Shape:YellowMolecular weight:328.43N-Deshydroxyethyl Dasatinib
CAS:Controlled ProductFormula:C20H22ClN7OSColor and Shape:Off-WhiteMolecular weight:443.95(E)-6-Iodo-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
CAS:Purity:98%Molecular weight:431.2770080566406(E)-2-((1-Acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity)
CAS:Purity:97%Color and Shape:SolidMolecular weight:428.51Levofloxacin Hemihydrate
CAS:<p>Applications Levofloxacin Hemihydrate is a S-(-) form of Ofloxacin (O245750), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992); North, D.S., et al.: Pharmacotherapy, 18, 915 (1998); Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003);<br></p>Formula:C18H20FN3O4·H2OColor and Shape:Light YellowMolecular weight:740.754'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile
CAS:Controlled Product<p>Impurity Irbesartan Cyano Impurity<br>Applications A butyldiazaspirononenone derivative used in the preparation of acetylcholinesterase inhibitors. An impurity found in Irbesartan (I751000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kavitha, C.V. et al.: Bioorg. Med. Chem., 15, 7391 (2007);<br></p>Formula:C25H27N3OColor and Shape:NeatMolecular weight:385.50Fluralaner-13C2,15N,D2
CAS:Controlled ProductFormula:C2C20D2H15Cl2F615NN2O3Color and Shape:Off-WhiteMolecular weight:561.276Benzhydrol
CAS:<p>Impurity Diphenhydramine EP Impurity D<br>Applications Intermediate in the preparation of Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Formula:C13H12OColor and Shape:WhiteMolecular weight:184.23Norfloxacin-d5
CAS:Controlled Product<p>Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>Formula:C162H5H13FN3O3Color and Shape:NeatMolecular weight:324.36Prochlorperazine
CAS:Controlled Product<p>Applications Prochlorperazine is antiemetic, antipsychotic; used in treatment of vertigo.<br>References Taylor, W.B., et al.: Br. J. Clin. Pharmacol., 23, 137 (1987), Ward, A.E., Br. J. Clin. Pract., 42, 228 (1988),<br></p>Formula:C20H24ClN3SColor and Shape:YellowMolecular weight:373.94Rilpivirine HCl
CAS:<p>Rilpivirine HCl (Rilpivirine hydrochloride) is an NNRTI inhibitor with antiviral activity that inhibits the HIV virus.</p>Formula:C22H19ClN6Purity:99.48%Color and Shape:SolidMolecular weight:402.88N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
CAS:Purity:95.0%Molecular weight:396.6700134277344Cinitapride Tartrate
CAS:<p>Applications Cinitapride Tartrate is the salt analogue of Cinitapride (C441990), a novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors.<br>References Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997); Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007); Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)<br></p>Formula:C21H30N4O4·C4H6O6Color and Shape:NeatMolecular weight:552.574,6-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.36999511718756-chloro-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS:Purity:90.0%Molecular weight:284.700012207031254-Amino-3,5-dichloropyridine
CAS:<p>Applications 4-Amino-3,5-dichloropyridine is a metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).<br>References Jeffrey, A.D. et al.: Drug Chem. Toxicol., 25, 93 (2002); Cassidy, K.C. et al.: J. Pharmac. Biomed. Anal., 22, 869 (2000);<br></p>Formula:C5H4Cl2N2Color and Shape:NeatMolecular weight:163.0S-[5-Chloro-3-(trifluoromethyl)pyrid-2-yl]-S-methylsulfilimine 2,4,6-trimethylbenzenesulfonate
CAS:Formula:C16H18ClF3N2O3S2Purity:95.0%Molecular weight:442.9Cilnidipine
CAS:Controlled Product<p>Applications A dihydropyridine calcium channel blocker.<br>References Ikeda, K., et al.: Oyo Yakuri, 44, 433 (1992), Hosono, M., et al.: J. Pharmacobio-Dyn., 15, 547, (1992), Ishii, M.: Japan Pharmacol. Ther., 21, 59 (1993),<br></p>Formula:C27H28N2O7Color and Shape:NeatMolecular weight:492.523-methyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-5-amine
CAS:Purity:95.0%Molecular weight:256.32998657226567-Chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:335.690002441406253-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Formula:C15H12N2O2Color and Shape:NeatMolecular weight:252.27N4-(3-Chloro-4-fluorophenyl)-7-ethoxyquinazoline-4,6-diamine (Afatinib Impurity)
CAS:Purity:97%Molecular weight:332.762-[5-amino-3-(2-furyl)-1H-pyrazol-1-yl]-5,6-dimethylpyrimidin-4(3H)-one
CAS:Purity:95.0%Molecular weight:271.27999877929696-Des(1-methyl-2-benzimidazolyl)-6-carboxy Telmisartan
CAS:Controlled Product<p>Impurity Telmisartan EP Impurity E / Telmisartan Diacid<br>Applications An impurity of Telmisartan (T017000).<br>References Yu, W. et al.: Youji Huaxue, 26, 318 (2006);<br></p>Formula:C26H24N2O4Color and Shape:NeatMolecular weight:428.49Oxcarbazepine
CAS:<p>Applications A metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989); Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001);<br></p>Formula:C15H12N2O2Color and Shape:Light YellowMolecular weight:252.27[1-(2-thienyl)butyl]amine hydrochloride
CAS:Formula:C8H14ClNSPurity:95.0%Color and Shape:SolidMolecular weight:191.72Gabapentin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Gabapentin is an Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Formula:C9H17NO2Color and Shape:NeatMolecular weight:171.24Domperidone
CAS:<p>Applications A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone (Motilium) is a dopamine blocker and an antidopaminergic reagent.<br>References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),<br></p>Formula:C22H24ClN5O2Color and Shape:White To Off-WhiteMolecular weight:425.912-(4-Benzyl-morpholin-2-ylmethyl)-isoindole-1,3-dione
CAS:Purity:95.0%Molecular weight:336.3909912109375Ioversol
CAS:Controlled Product<p>Applications Nonionic, low osmolality, radiographic contrast agent. Diagnostic aid (radiopaque medium).<br>References Wilkins, R.A., et al.: Invest. Radiol., 24, 781 (1989), Kaufman, A.J., et al.: Urol. Radiol., 12, 56 (1990),<br></p>Formula:C18H24I3N3O9Color and Shape:Off-WhiteMolecular weight:807.116-Bromo-5-methylpicolinic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:216.03399658203125OSI-420, Free Base (Desmethyl Erlotinib)
CAS:Controlled ProductFormula:C21H21N3O4Color and Shape:NeatMolecular weight:379.41Ofloxacin
CAS:<p>Applications Ofloxacin is a fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990);<br></p>Formula:C18H20FN3O4Color and Shape:Off-WhiteMolecular weight:361.37Monepantel
CAS:<p>Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.</p>Formula:C20H13F6N3O2SPurity:99.83%Color and Shape:White PowderMolecular weight:473.396-chloro-4-methyl-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:289.77999877929691-(3-Carboxypropyl)-3,7-dimethylxanthine
CAS:Controlled Product<p>Applications A metabolite of Pentoxifylline (P276500).<br>References Yamaoka, K., et al.: J. Pharmacokin. Biopharm., 6, 165 (1978), Cottam, H.B., et al.: J. Med. Chem., 39, 2 (1996), Janvilisri, T., et al.: J. Biol. Chem., 278, 20645 (2003),<br></p>Formula:C11H14N4O4Color and Shape:NeatMolecular weight:266.25
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