Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65495 products of "Quinazoline and Quinoline Derivatives"
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5-(1,3-Dioxolan-2-yl)-2-(4-hexyloxybenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:360.4700012207031Chlorpromazine N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Chlorpromazine N-Oxide is a metabolite of Chlorpromazine. Chlorpromazine exhibits antiadrenergic, antiserotonergic, anticholinergic, and antihistaminergic properties, and commonly used to treat schizophrenia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, Z., et al.: Handbook of Metabolic Pathways of Xenobiotics, 3, 1102 (2014); Kigondu, E. M., et al.: MedChemComm, 5, 502 (2014); Yeung, P. K. F., et al.: Eur. J. Clin. Pharmacol., 45, 563 (1993)<br></p>Formula:C17H19ClN2OSColor and Shape:NeatMolecular weight:334.867-chloro-4-methyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:289.7799987792969N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
CAS:Purity:95.0%Molecular weight:396.67001342773444-Chloro-7-(3,5-dimethylisoxazol-4-yl)-6-methoxyquinoline-3-carboxamide
CAS:Purity:97%Molecular weight:331.7600097656257-Despropyl 7-Methyl Vardenafil
Controlled Product<p>Applications 7-Despropyl 7-Methyl Vardenafil is an impurity of Vardenafil (V098001, 2HCl); a selective phosphodiesterase type 5 (PDE5) inhibitor.<br>References Bischoff, E., et al.: J. Urol., 165, 1316 (2001); Kim, N.N., et al.: Life Sci., 69, 2249 (2001); Kendirci, M., et al.: Expert Opin. Pharmacother., 5, 923 (2004)<br></p>Formula:C21H28N6O4SColor and Shape:Off White SolidMolecular weight:460.555-(2-Thioxo-2,3-dihydrothiazol-4-yl)thiophene-2-carboxamide
CAS:Formula:C8H6N2OS3Purity:95%Molecular weight:242.33Valsartan Ethyl Ester
CAS:Controlled Product<p>Applications Valsartan Ethyl Ester is an impurity of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Formula:C26H33N5O3Color and Shape:White To Light BeigeMolecular weight:463.574-(Benzyloxy)picolinonitrile
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:210.23599243164062N-Nitrosometoprolol
CAS:<p>Applications N-Nitrosometoprolol is an N-nitroso derivative of rac Metoprolol(M338815), which is a β1 selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. N-Nitrosometoprolol can be used to assess human and rat hepatocytes.<br>References McGourty, J.C., et al.: Br. J. Clin. Pharmacol. 20, 555 (1985); Lennard, M.S., et al.: Biochem. Pharmacol., 35, 2757 (1986); Martelli, A., In Vivo, 11, 189-194, (1997);<br></p>Formula:C15H24N2O4Color and Shape:Colourless To Light YellowMolecular weight:296.365-chloro-2-(1H-pyrazol-5-yl)aniline
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:193.63000488281255-Amino-1-benzo[1,3]dioxol-5-yl-1H-pyrazole-4-carbonitrile
Purity:95.0%Molecular weight:228.210998535156253-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid
CAS:Controlled ProductFormula:C16H21N5O3Color and Shape:NeatMolecular weight:331.37Avanafil
CAS:Controlled Product<p>Applications A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.<br>References Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008);<br></p>Formula:C23H26ClN7O3Color and Shape:WhiteMolecular weight:483.953-(1-Pyridin-4-yl-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid
CAS:Purity:90.0%Molecular weight:282.3429870605469Cobicistat
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Cobicistat is a HIV protease inhibitor and has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer, significantly increasing their plasma concentrations.<br>References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012);<br></p>Formula:C40H53N7O5S2Color and Shape:NeatMolecular weight:776.02PTC-124
CAS:Controlled Product<p>Applications PTC-124 is a nonaminoglycoside that has been reported to induce ribosomes to read through premature nonsense stop signals on mRNA, allowing the production of full-length functional proteins,<br>References Yu, H. et al.: Int. J. Mol. Med., 33, 729 (2014); Aditya, S. et al.: J. Biomed. Pharm. Res., 2, 21 (2013);<br></p>Formula:C15H9FN2O3Color and Shape:White To Off-WhiteMolecular weight:284.24N-Nitroso Temocapril
Controlled ProductFormula:C23H27N3O6S2Color and Shape:NeatMolecular weight:505.6Decoquinate
CAS:Controlled Product<p>Applications Decoquinate is a quinolone coccidiostat used in veterinary medicine, in particular as animal feed for poultry.<br>References Del Cacho, E. et al.: Int. J. Parasitol., 36, 1515 (2006); Guo, F.C. et al.: Vet. Parasitol., 147, 239 (2007); Davis, J.L. et al.: Vet. Pharmacol. Therap., 9, 1145 (2009);<br></p>Formula:C24H35NO5Color and Shape:Off-WhiteMolecular weight:417.544-(Trifluoromethyl)aniline
CAS:Controlled Product<p>Impurity Leflunomide EP Impurity A; Leflunomide USP Related Compound A<br>Applications 4-(Trifluoromethyl)aniline (Leflunomide EP Impurity A; Leflunomide USP Related Compound A) is a 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weber, W., et al.: Pharmacol. Rev., 37, 25 (1985), Hein, D., et al.: Carcinogenesis, 14, 1633 (1993), Payton, M., et al.: Microbiology, 147, 1137 (2001), Mushtaq, A., et al.: J. Biol. Chem., 277, 12175 (2002),<br></p>Formula:C7H6F3NColor and Shape:NeatMolecular weight:161.12Ambrisentan Methyl Ester
CAS:Controlled Product<p>Applications (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate is a useful intermediate in the preparation of Ambrisentan. Ambrisentan is an Antihypertensive. Ambrisentan Impurity (A575860).<br>References Peng, X., et al.: J. Org. Chem., 77, 701 (2012), Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003)<br></p>Formula:C23H24N2O4Color and Shape:Off-WhiteMolecular weight:392.45Vildagliptin-d3
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Vildagliptin. It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H22D3N3O2Color and Shape:NeatMolecular weight:306.42cis-(Z)-Flupentixol Dihydrochloride
CAS:Controlled Product<p>Applications Neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.<br>References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),<br></p>Formula:C23H27Cl2F3N2OSColor and Shape:NeatMolecular weight:507.44Salsalate-d8
CAS:Controlled Product<p>Applications Isotope labelled Nonacetylated aspirin analog. Analgesic, anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, L.L., et al.: J. Pharm. Sci., 69, 1268 (1980), Dromgoole, S.M., et al.: J. Pharm. Sci., 73, 1657 (1984),<br></p>Formula:C14H2D8O5Color and Shape:NeatMolecular weight:266.282-Cyclopropyl-quinoline-4-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:213.235992431640623-Hydroxybenzaldehyde
CAS:<p>Impurity Roxatidine Impurity 3<br>Applications 3-Hydroxybenzaldehyde (cas# 100-83-4) is a compound useful in organic synthesis.<br></p>Formula:C7H6O2Color and Shape:Off-WhiteMolecular weight:122.12Dolutegravir Sodium
CAS:<p>Applications Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011)<br></p>Formula:C20H18F2N3O5·NaColor and Shape:NeatMolecular weight:441.365-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
CAS:Controlled Product<p>Applications 5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is useful for the synthesis of 5-Bromo-7-azaindolin-2-one derivatives which possesses in vitro activity against selected cancer cell lines.<br>References Zhang, J., et al.: Molecules, 21, 1674-1683 (2016);<br></p>Formula:C8H9NO3Color and Shape:NeatMolecular weight:167.16rac-Ruxolitinib-d9 (major)
CAS:Controlled Product<p>Applications Labelled racemic analogue of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.<br>References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);<br></p>Formula:C17H9D9N6Color and Shape:White To Light YellowMolecular weight:315.424-Amino Fluconazole Bromide
CAS:<p>Impurity Fluconazole EP Impurity I<br>Applications 4-Amino Fluconazole Bromide (Fluconazole EP Impurity I) is an impurity of Fluconazole (F421000), which is used as an antifungal.<br>References Richard, K. et al.: Antimicrob. Ag. Chemother., 27, 832 (1985)<br></p>Formula:C13H14F2N7O·BrColor and Shape:NeatMolecular weight:402.20(+/-)-4-Hydroxy Mephenytoin
CAS:Controlled Product<p>Applications CYP2C19 metabolite of Mephenytoin.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980)<br></p>Formula:C12H14N2O3Color and Shape:White SolidMolecular weight:234.254,5-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.36999511718757-Nitro-4-(pyridin-2-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
CAS:Purity:95+%Molecular weight:285.2590026855469Ref: 10-F608382
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire2-(4-Chlorophenoxy)aniline
CAS:Controlled Product<p>Applications Amoxapine impurity.<br>References Matsuo, M., et al.: Chem. Pharma. Bull., 33, 4409 (1985),<br></p>Formula:C12H10ClNOColor and Shape:NeatMolecular weight:219.67Aripiprazole N1-Oxide
CAS:Controlled Product<p>Impurity Aripiprazole EP Impurity F<br>Stability Hygroscopic<br>Applications Aripiprazole N1-Oxide (Aripiprazole EP Impurity F) is a metabolite of anti-psychotic drug, Aripiprazole (A771000).<br>References Rowley, M., et al.: J. Med. Chem., 44, 477 ( 2001), Ozdemir, V., et al.: Curr. Opin. Invest Drugs 2002, 3, 113,,,4) Jordan, S; European Journal Pharmacol 2002, 441, 137<br></p>Formula:C23H27Cl2N3O3Color and Shape:NeatMolecular weight:464.38Levetiracetam Carboxylic Acid
CAS:Controlled ProductFormula:C8H13NO3Color and Shape:White To Off-WhiteMolecular weight:171.192-Chloro-5-(5-Chloro-2-thienyl)pyridine
CAS:Formula:C9H5Cl2NSPurity:97.0%Color and Shape:SolidMolecular weight:230.113-[(pyridin-3-ylamino)carbonyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS:Purity:95.0%Molecular weight:258.2770080566406Phenothrin (>85%)
CAS:Controlled Product<p>Applications Phenothrin is a pesticide used in the control of pests and insects. It is used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, Y. et al.: Chemopshere, 90, 848 (2013); Hirahara, Y. et al.: Japan. J. Toxicol. Env. Health, 44, 451 (1998);<br></p>Formula:C23H26O3Purity:>85%Color and Shape:Light YellowMolecular weight:350.45Defluoro Levofloxacin
CAS:<p>Impurity Levofloxacin USP Related Compound F<br>Applications Nonfluorinated analog of Levofloxacin (L360000). Levofloxacin USP Related Compound F.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Fujita, M., et al.: Chem. Pharm. Bull., 44, 987 (1996), Graul, A., et al.: Drugs Future, 24, 1324 (1999), Takahata, M., et al.: Antimicrob. Agents Chemother., 43, 1077 (1999),<br></p>Formula:C18H21N3O4Color and Shape:Off-WhiteMolecular weight:343.386-Hydroxy-3,4-dihydro-1H-quinoline-2-one
CAS:Controlled Product<p>Impurity Cilostazol USP Related Compound A<br>Applications A metabolite of Cilostazole.<br>References Gitto, R., et al.: J. Med. Chem., 46, 3758 (2003), Xie, Z., et al.: Bioorg. Med. Chem. Lett., 15, 4803 (2005),<br></p>Formula:C9H9NO2Color and Shape:NeatMolecular weight:163.17Apixaban-d3
CAS:Controlled Product<p>Applications Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C25H22D3N5O4Color and Shape:White To Off-WhiteMolecular weight:462.52N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-nitroquinazolin-4-yl)acetamide
CAS:Purity:97.0%Molecular weight:390.760009765625
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