Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65495 products of "Quinazoline and Quinoline Derivatives"
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N-Nitroso Desmethyl Olopatadine
Controlled ProductFormula:C20H20N2O4Color and Shape:NeatMolecular weight:352.384N,N'-Methylene Ambroxol Hydrochloride
CAS:Controlled Product<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Formula:C14H18Br2N2O·ClHColor and Shape:White To Off-WhiteMolecular weight:426.57N-Benzyl Hydroxymedetomidine
CAS:Controlled Product<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Formula:C20H22N2OColor and Shape:NeatMolecular weight:306.45-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone
CAS:<p>Impurity Domperidone EP Impurity A<br>Applications 5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone (Domperidone EP Impurity A) is a metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).<br>References Meuldermans, W. et al.: Eur. J. Drug Metab. Pharmacokin., 6, 49 (1981); Simard, C. et al.: Xenobiotica, 34, 1013 (2004);<br></p>Formula:C12H14ClN3OColor and Shape:NeatMolecular weight:251.711,3-Dioxo-2-pyridin-3-ylmethyl-2,3-dihydro-1H-isoindole-5-carboxylic acid
CAS:Purity:95.0%Molecular weight:282.2550048828125Ethyl 6-ethynylpicolinate
CAS:Formula:C10H9NO2Purity:98%Color and Shape:Liquid, No data available.Molecular weight:175.187Bicalutamide-d4
CAS:Controlled Product<p>Applications Used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0)<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Formula:C18H10D4F4N2O4SColor and Shape:NeatMolecular weight:434.42-(6-methylpyridin-2-yl)-1,3-dioxoisoindoline-5-carboxylic acid
CAS:Purity:95.0%Molecular weight:282.2550048828125Methyl 2-amino-4-(3,4-dimethylphenyl)-5-methylthiophene-3-carboxylate
CAS:Formula:C15H17NO2SPurity:97%Color and Shape:SolidMolecular weight:275.375-methoxy-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:271.33999633789064-(1H-Pyrazol-4-yl)quinoline
CAS:Purity:95.0%Color and Shape:Solid, Crystalline PowderMolecular weight:195.225006103515628-propyl-4-(pyridine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:333.388000488281254-Methoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS:Formula:C7H6N2O2Purity:97%Color and Shape:SolidMolecular weight:150.1375-Nitro-1 H -pyrazole-3-carboxylic acid (2-amino-ethyl)-amide
CAS:Formula:C6H9N5O3Color and Shape:SolidMolecular weight:199.172-(Chloromethyl)-6-methoxypyridine
CAS:Formula:C7H8ClNOPurity:95.0%Color and Shape:LiquidMolecular weight:157.64-(furan-2-yl)-6-(3-methylthiophen-2-yl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:257.30999755859375Celecoxib-d7
CAS:Controlled Product<p>Applications Celecoxib-d7 is the labeled analogue of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998); Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000); Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000)<br></p>Formula:C17D7H7F3N3O2SColor and Shape:WhiteMolecular weight:388.422-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:361.26998901367194-Ethoxy-3-nitropyridine hydrochloride
CAS:Purity:95.0%Color and Shape:Solid, White to cream coloured powderMolecular weight:204.61000061035156N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
CAS:Purity:95.0%Molecular weight:396.67001342773445-Methyl-2-(tetrahydropyran-4-yl)-2H-pyrazol-3-ylamine
CAS:Color and Shape:SolidMolecular weight:181.238998413085941-[3-(Trifluoromethyl)pyrid-2-yl]piperazine
CAS:Formula:C10H12F3N3Purity:98%Color and Shape:Solid, Low Melting SolidMolecular weight:231.2221-(3-Nitropyridin-2-yl)piperidine-4-carbonitrile
CAS:Formula:C11H12N4O2Purity:95.0%Molecular weight:232.2435-(CHLOROMETHYL)-3-(3-PHENOXYPYRIDIN-4-YL)-1,2,4-OXADIAZOLE
Purity:95.0%Molecular weight:287.700012207031253,5-Dinitrosalicylhydrazide-15N2
CAS:Controlled Product<p>Applications Labelled Nifursol (N458700) metabolite.<br>References Shen, Y. et al.: Faming Zhuanli Shenqing 13 (2009)<br></p>Formula:C7H6N215N2O6Color and Shape:Light YellowMolecular weight:244.134’-O-Benzyloxy Ezetimibe
CAS:Controlled Product<p>Impurity Ezetimibe Benzyl Ether Impurity<br>Applications Protected Ezetimibe, used for the synthesis of related derivatives.<br>References Raman, B., et al.: J. Pharm. Biomed. Anal., 52, 73 (2010),<br></p>Formula:C31H27F2NO3Color and Shape:NeatMolecular weight:499.55N-Desmethyl Diphenhydramine Hydrochloride
CAS:<p>Applications N-Desmethyl Diphenhydramine is an impurity of Diphenhydramine (D486900) with antihistaminic activity.<br>References Nauta, W. T. et al.: Med. Chem., Spec. Contrib. Int. Symp., 3rd, 125 (1973);<br></p>Formula:C16H19NO·ClHColor and Shape:White To Light BeigeMolecular weight:277.79Iso Loratadine
CAS:Controlled Product<p>Impurity Loratadine EP Impurity E<br>Applications Iso Loratadine (Loratadine EP Impurity E) is a Loratadine (L469575) impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.<br>References Billah., et al.: Lipids, 26, 1172 (1991), Piwinski., et al.: J. Med. Chem., 34, 457 (1991),<br></p>Formula:C22H23ClN2O2Color and Shape:NeatMolecular weight:382.881-(6,7-Dimethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbamate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:360.414001464843755-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Purity:95.0%Molecular weight:216.24000549316406Terfuboxon
CAS:Controlled Product<p>Applications Terfuboxon is a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br>References Rahman, Md. M. et al.: Food CHem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008);<br></p>Formula:C9H21O3PS2Color and Shape:NeatMolecular weight:272.36Ondansetron-d3 Hydrochloride Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000),<br></p>Formula:C18H16D3N3O•HClColor and Shape:NeatMolecular weight:296.393646Deshydroxy Bicalutamide
CAS:Controlled Product<p>Impurity Bicalutamide EP Impurity C<br>Applications Deshydroxy Bicalutamide (Bicalutamide EP Impurity C) is an impuirty of Bicalutamide. Bicalutamide intermediate.<br>References Lysiak, V., et al.: Bioorg. Med. Chem., 13, 671 (2005),<br></p>Formula:C18H14F4N2O3SColor and Shape:Off-WhiteMolecular weight:414.376-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline
CAS:Controlled Product<p>Impurity Efavirenz USP Related Compound C/ Efavirenz Quinoline Impurity<br>Applications 6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline is an impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor and antiviral agent.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995), Jiang, B., et al.: Euro. J. Org. Chem., 16, 2693 (2008); Ribeiro, J.A., et al.: J. Pharma. Biomed. Anal., 43, 298 (2007);<br></p>Formula:C13H9ClF3NColor and Shape:NeatMolecular weight:271.67Piperazin-1-yl(quinoxalin-6-yl)methanone hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:278.739990234375(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
CAS:Controlled Product<p>Applications (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.<br>References Kim, H.J., et. al.: Bioorg. Med. Chem. Lett., 22, 5545 (2012)<br></p>Formula:C15H18F3NO4Color and Shape:NeatMolecular weight:333.30
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