Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4949 products of "Steroids and Derivatives"
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Androsterone
CAS:Controlled Product<p>Applications A steroid hormone with weak androgenic activity. It is metabolized from Testosterone (T155000) in the liver and is used in doping analysis to detect testosterone misuse. Controlled Substance.This compound is a contaminant of emerging concern (CECs).<br>References Park, J., et al.: J. Anal. Toxicol., 14, 66 (1990), Palonek, E., et al.: J. Steroid Mol. Biol., 55, 121 (1995), Aguilera, R., et al.: Clin. Chem. 47, 292 (2001), Flenker, U., et al.: Steroids, 73, 408 (2008),<br></p>Formula:C19H30O2Color and Shape:White To Off-WhiteMolecular weight:290.4411α-Hydroxy Progesterone
CAS:Controlled Product<p>Applications Progesterone (P755900) metabolite.<br>References Christy H., et al.: J. Steroid Biochem., Mol., Biol., 116, 171 (2009), Peristera, O., et al.: Toxicol., Lett., 189, 219 (2009), Mori, T., et al.: Toxicol., Lett., 186, 123 (2009),<br></p>Formula:C21H30O3Color and Shape:Off-WhiteMolecular weight:330.463b,5a,6b-Trihydroxycholestane
CAS:<p>Applications Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity.<br>References Watson, K., et al.: J. Clin. Invest., 93, 2106 (1994), Wada, T., et al.: Circ. Res., 84, 166 (1999), Engelse, M., et al.: Cardiovasc. Res., 52, 281 (2001), Landis, M., et al.: J. Biol. Chem., 277, 4713 (2002),<br></p>Formula:C27H48O3Color and Shape:NeatMolecular weight:420.6711-Dehydrodexamethasone
CAS:Controlled ProductFormula:C22H27FO5Color and Shape:NeatMolecular weight:390.4452Zilpaterol-d7
CAS:Controlled Product<p>Applications b-Adrenergic agonist. Zipaterol, is used to promote growth. Zilpaterol is used to increase the size of cattle.<br>References Shelver, W.L., et al.: J. Agric. Food Chem., 52, 2159 (2004),<br></p>Formula:C14H12D7N3O2Color and Shape:Light BrownMolecular weight:268.36Isoflupredone Acetate
CAS:Controlled Product<p>Applications An anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.<br>References Coffer, N.Y. et al.: Am. J. Vet. Res., 67, 1244 (2006); Seifi, H.A. et al.: J. Diary Sci., 90, 4181 (2007);<br></p>Formula:C23H29FO6Color and Shape:Off-WhiteMolecular weight:420.473(R,S)-Hydroxy Desogestrel
CAS:Controlled Product<p>Applications A metabolite of Desogestrel.<br>References Back, D., et al.: Br. J. Clin. Pharmacol., 26, 23 (1988), Wienkers, L., et al.: Drug Metab. Dispos., 1990, 24, 610 (1990), Bourrie, M., et al.: J. Pharmacol. Exp. Ther., 277, 321 (1996), Ono, S., et al.: Xenobiotica, 26, 681 (1996),<br></p>Formula:C22H30O2Color and Shape:NeatMolecular weight:326.473-Keto Fluvastatin Sodium Salt
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications An impurity of Fluvastatin.<br></p>Formula:C24H23FNO4·NaColor and Shape:NeatMolecular weight:431.43Betamethasone-∆17,20 21-Aldehyde(Mixture of Isomers)
CAS:Controlled Product<p>Applications A degradation and metabolic intermediate of Betamethasone (B3270000).<br></p>Formula:C22H27FO4Color and Shape:NeatMolecular weight:374.45Fulvestrant
CAS:Controlled ProductFormula:C32H47F5O3SColor and Shape:White To Off-WhiteMolecular weight:606.77di(2-Hydroxy Atorvastatin-d5) Calcium Salt
CAS:Controlled Product<p>Applications di(2-Hydroxy Atorvastatin-d5) Calcium Salt is the labeled analogue of di(2-Hydroxy Atorvastatin) Calcium Salt (H828930), a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C66H58D10CaF2N4O12Color and Shape:NeatMolecular weight:1197.42Pregna-4,9(11)-diene-3,20-dione (90%)
CAS:Controlled Product<p>Applications Pregna-4,9(11)-diene-3,20-dione is a Progesterone (P755900) impurity, a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.<br>References Thomas, P. et al.: Endocrinol., 148, 705 (2007); Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formula:C21H28O2Purity:90%Color and Shape:NeatMolecular weight:312.45Testosterone-d3 β-D-Glucuronide Monosodium Salt
CAS:Controlled Product<p>Applications Labelled Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug<br></p>Formula:C25H32D3NaO8Color and Shape:Off-WhiteMolecular weight:489.55Digoxigenin Bisdigitoxoside
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Formula:C35H54O11Color and Shape:NeatMolecular weight:650.80Testosterone Undecylenate
CAS:Controlled Product<p>Applications Testosterone Undecylenate is an ester metabolite of Testosterone (T155000), which is the main hormone of the testes, produced by the interstitial cells. It is a major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone that is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.<br>References McFarland, K., et al.: Science, 245, 494 (1989); Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000); Kumar, R., et al.: Biol. Reprod., 65, 710 (2001);<br></p>Formula:C30H46O3Color and Shape:NeatMolecular weight:454.684Andarine
CAS:Controlled Product<p>Applications It is a potent and tissue-selective androgen receptor modulator (SARM) used as antiosteoporotic agent.<br>References Samnegard, E., et al.: Bone, 28, 414 (2001), Hanada, K., et al.: Biol. Pharm. Bull., 26, 1563 (2003), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Pharm. Res., 24, 328 (2007),<br></p>Formula:C19H18F3N3O6Color and Shape:Light YellowMolecular weight:441.3621-Deoxy Cortisone
CAS:Controlled Product<p>Applications A Cortisone derivative, a glucocorticoid.<br>References Mickelson, K., et al.: Biochemistry, 20, 6211 (1981), Westphal, U., et al.: J. Steroid Biochem., 19, 1 (1983),<br></p>Formula:C21H28O4Color and Shape:NeatMolecular weight:344.444-Hydroxy Estradiol 1-N7-Guanine
CAS:Controlled Product<p>Applications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Formula:C23H27N5O4Color and Shape:NeatMolecular weight:437.4916α-Methyl-11-oxo Prednisolone
CAS:Controlled Product<p>Applications A 16α-substituted Prednisolone as potent topical antiinflammatory agent.<br>References Lutsky, B.N., et al.: Arzneim.-Forsch., 29, 1662 (1979),<br></p>Formula:C22H28O5Color and Shape:White SolidMolecular weight:372.4517-Iodo-androsta-5,16-diene-3β-ol
CAS:Controlled Product<p>Impurity Abiraterone Impurity 5<br>Applications 17-Iodo-androsta-5,16-diene-3β-ol is an analog of Abiraterone (A108490) and is used as a reagent in the synthesis of C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens which exhibit antitumor activity. Abiraterone Impurity 5<br>References Handratta, V.D., et al.: J. Med. Chem., 48, 2972 (2005)<br></p>Formula:C19H27IOColor and Shape:White To Off-WhiteMolecular weight:398.32
