Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4949 products of "Steroids and Derivatives"
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3α-Hydroxy Tibolone
CAS:Controlled Product<p>Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),<br></p>Formula:C21H30O2Color and Shape:White To Off-WhiteMolecular weight:314.469,11-Dehydro Ethynyl Estradiol
CAS:<p>Impurity Ethinylestradiol EP Impurity B<br>Applications 9,11-Dehydro Ethynyl Estradiol (Ethinylestradiol EP Impurity B) is a degradation product of Ethynyl Estradiol (EE); an impurity of Ethynyl Estradiol (E685100).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pang, C., et al.: Steroids, 23, 203 (1974), Leese, M., et al.: J. Med. Chem., 49, 7683 (2006), Krstic, N., et al.: Steroids, 72, 406 (2007),<br></p>Formula:C20H22O2Color and Shape:NeatMolecular weight:294.39Prednisolone 21-β-D-Glucuronide
CAS:<p>Applications Prednisolone 21-β-D-Glucuronide Sodium Salt is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Formula:C27H35NaO11Color and Shape:NeatMolecular weight:558.551-Chloro Dihydro Dutasteride
CAS:<p>Impurity Dutasteride EP Impurity F<br>Applications 1-Chloro Dihydro Dutasteride (Dutateride EP Impurity F) is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride (D735000).<br></p>Formula:C27H31ClF6N2O2Color and Shape:NeatMolecular weight:564.99Spironolactone-d3
CAS:Controlled Product<p>Applications Spironolactone-d3 is the labeled analogue of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975)<br></p>Formula:C24H29D3O4SColor and Shape:Yellow SolidMolecular weight:419.5922α-Hydroxy Cholesterol
CAS:Controlled Product<p>Applications The 22R-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.<br>References Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),<br></p>Formula:C27H46O2Color and Shape:NeatMolecular weight:402.65Norgestrel
CAS:Controlled Product<p>Applications Norgestrel is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.<br>References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),<br></p>Formula:C21H28O2Color and Shape:White To Off-WhiteMolecular weight:312.456β-Hydroxy Testosterone
CAS:Controlled ProductFormula:C19H28O3Color and Shape:WhiteMolecular weight:304.4217α-Hydroxy Progesterone-d8
CAS:Controlled Product<p>Applications Labelled 17α-Hydroxyprogesterone (H952330). 17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formula:C212H8H22O3Color and Shape:Off-WhiteMolecular weight:338.51(6a,11b,16b)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (6α,11β,16β)-6-Bromo-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione is a derivative of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Formula:C22H28BrFO5Color and Shape:NeatMolecular weight:471.36Estradiol Benzoate
CAS:<p>Applications Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.<br>References MacLusky, N., et al.: Endocrinology, 106, 192 (1980), Apostolakis, E., et al.: J. Neurosci., 16, 4823 (1996), Guarraci, F., et al.: Brain Res., 999, 40 (2004), Petralia, S., et al.: J. Neuroendocrinol., 18, 902 (2006),<br></p>Formula:C25H28O3Color and Shape:WhiteMolecular weight:376.49Dexamethasone 9,11-Epoxide-d5
CAS:Controlled Product<p>Applications Dexamethasone 9,11-Epoxide-d5, is the labeled analogue of the unlabeled (D298795 ), a Dexamethasone intermediate.<br>References Isogai, M., et al.: J. Steroid Biochem. Mol. Biol., 44, 141 (1993),<br></p>Formula:C22H23D5O5Color and Shape:Off-WhiteMolecular weight:377.491α-(Chloromethyl) Chlormadinone Acetate
CAS:Controlled Product<p>(1α)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)-pregna-4,6-<br>diene-3,20-dione; 6-Chloro-1α-(chloromethyl)-17-<br>hydroxypregna-4,6-diene-3,20-dione Acetate; Cyproterone<br>Acetate EP Impurity C</p>Formula:C24H30Cl2O4Color and Shape:NeatMolecular weight:453.40Estradiol Cypionate
CAS:<p>Applications Estradiol Cypionate is present in injectable contraceptive formulations. Used in hormone replacement therapy with potential for improving cognition in post-menopausal women.<br>References Thurman, A. et al.: Contra., 87, 738 (2013); Sales, J. et al.: Theriogen., 78, 510 (2012); Rapp, P. et al.: J. neurosci., 23, 5708 (2003);<br></p>Formula:C26H36O3Color and Shape:NeatMolecular weight:396.56trans-Diethyl Stilbestrol
CAS:Controlled Product<p>Stability And Ether., Chloroform, Isomerizes Rapidly In Benzene<br>Applications A synthetic, nonsteroidal estrogen.Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References White, W. A. et. al.: J. Agric. Food Chem. 19(2), 388-390 (1971).<br></p>Formula:C18H20O2Color and Shape:NeatMolecular weight:268.356-β-Hydroxy Eplerenone
CAS:<p>Applications A metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br></p>Formula:C24H30O7Color and Shape:White To Off-WhiteMolecular weight:430.49Dydrogesterone
CAS:Controlled Product<p>Applications A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.<br>References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45(17α)-19-Norpregna-3,5-dien-20-yne-3,17-diol 3,17-Diacetate
CAS:Controlled Product<p>Applications Inhibits the development of uterus decidua. Estrogenic activity.<br>References Pollard, I. & Martin, L.; Steroids, 11, 897 (1968)<br></p>Formula:C24H30O4Color and Shape:White To Light YellowMolecular weight:382.4914,15-Dehydro Triamcinolone Acetonide
CAS:Controlled Product<p>Applications 14,15-Dehydro Triamcinolone Acetonide is a derivative of Triamcinolone acetonide. A corticosteroid.<br></p>Formula:C24H29FO6Color and Shape:Light YellowMolecular weight:432.4811-β-Hydroxyandrosterone
CAS:<p>Applications 11-β-Hydroxyandrosterone is a steroid metabolite of Andosterone (A637535), and is one of the major hormones monitored (in urine) when testing athletes for anabolic steroid usage.<br>References Flenker, U., et al.: Steroids, 73, 408 (2008); Norli, H., et al.: J. Steroid Biochem., 24, 83 (1995)<br></p>Formula:C19H30O3Color and Shape:NeatMolecular weight:306.44
