Peptides and Proteins
Peptides are short chains of amino acids linked by peptide bonds, whereas proteins are longer and more complex amino acid chains that can adopt functional three-dimensional structures. Both types of compounds are essential for various biological functions, such as catalysing reactions (enzymes), immune defence (antibodies), and cellular signalling. Proteins have a hierarchical structure, including the amino acid sequence, secondary, tertiary, and quaternary structures. Peptides are used in pharmaceutical and cosmetic therapies due to their specific biological properties, such as in the treatment of metabolic diseases or enhancing cellular regeneration. Proteins, on the other hand, have applications in biotechnology, nutrition, and regenerative medicine.
At CymitQuimica, we offer high-purity peptides and proteins for research in biotechnology and therapeutic applications.
Found 3116 products of "Peptides and Proteins"
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THAL-SNS-032
CAS:<p>THAL-SNS-032 is a selective CDK9 degrader PROTAC.</p>Formula:C40H52N8O10S2Purity:99.68%Color and Shape:SolidMolecular weight:869.02L-Proline
CAS:<p>L-Proline, a nonessential amino acid crucial for collagen synthesis, supports joint, tendon, and heart muscle health.</p>Formula:C5H9NO2Purity:98% - 98.05%Color and Shape:Flat Needles From Alcohol + Ether; Prisms From Water SolidMolecular weight:115.13dBET1
CAS:<p>dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.</p>Formula:C38H37ClN8O7SPurity:98.02% - 99.3%Color and Shape:SolidMolecular weight:785.27Bis(maltolato)oxovanadium(IV)
CAS:<p>BMOV: oral pan-PTP inhibitor, mimics insulin, anti-diabetic, improves heart function in diabetes, IC50s: 126-201 nM.</p>Formula:C12H10O7VPurity:99.65% - 99.918%Color and Shape:SolidMolecular weight:317.15Glecaprevir
CAS:<p>Glecaprevir (ABT-493) is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).</p>Formula:C38H46F4N6O9SPurity:99.16% - 99.69%Color and Shape:SolidMolecular weight:838.87Atosiban acetate
CAS:<p>Atosiban acetate (RW22164) is an inhibitor of the hormones oxytocin and vasopressin.</p>Formula:C45H71N11O14S2Purity:99.84% - 99.92%Color and Shape:SolidMolecular weight:1054.24BI-6015
CAS:<p>BI 6015 is an antagonist of HNF4α. HNF4α is a nuclear receptor that regulates gene expression in the intestine cells, liver cells, and pancreas-β cells.</p>Formula:C15H13N3O4SPurity:99.81%Color and Shape:SolidMolecular weight:331.35Daptomycin
CAS:<p>Daptomycin (LY146032) is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.</p>Formula:C72H101N17O26Purity:99.61% - >99.99%Color and Shape:White PowderMolecular weight:1620.67Urolithin C
CAS:<p>Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.</p>Formula:C13H8O5Purity:98.01% - 99.53%Color and Shape:SolidMolecular weight:244.2DC260126
CAS:<p>DC260126 is a small-molecule antagonist of FFA1 (GPR40)</p>Formula:C16H18FNO2SPurity:99.77%Color and Shape:SolidMolecular weight:307.38Deruxtecan
CAS:<p>Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker used in the synthesis of DS-8201 and U3-1402.Cost-effective and quality-assured.</p>Formula:C52H56FN9O13Purity:98.15% - 98.20%Color and Shape:SolidMolecular weight:1034.05Lanreotide Impurity 18 Ditrifluoroacetate (Kyn (For) 4)
Formula:C54H69N11O12S2·2C2HF3O2Molecular weight:1128.33 2* 114.02Lanreotide Impurity 16 Ditrifluoroacetate (L-Nal 1)
Formula:C54H69N11O10S2·2C2HF3O2Molecular weight:1096.33 2* 114.02Lanreotide Impurity 19 Ditrifluoroacetate (Kyn 4)
Formula:C53H69N11O11S2·2C2HF3O2Molecular weight:1100.32 2* 114.02Lanreotide Impurity 20 Ditrifluoroacetate (Dha 7)
Formula:C54H69N11O10S·2C2HF3O2Molecular weight:1064.27 2* 114.02Lanreotide Impurity 15 Ditrifluoroacetate (D-Tyr 3)
Formula:C54H69N11O10S2·2C2HF3O2Molecular weight:1096.33 2* 114.02Lanreotide Impurity 17 Ditrifluoroacetate (D-Cys 7)
Formula:C54H69N11O10S2·2C2HF3O2Molecular weight:1096.33 2* 114.02Lanreotide Impurity 21 Ditrifluoroacetate
Formula:C54H69N11O10S·2C2HF3O2Molecular weight:1064.27 2* 114.0Lopinavir-d8
CAS:Controlled Product<p>Applications A labelled selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.<br>References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)<br></p>Formula:C37D8H40N4O5Color and Shape:Light YellowMolecular weight:636.85Sacubitril Sodium Salt
CAS:Formula:C24H28NO5·NaColor and Shape:White To Off-WhiteMolecular weight:433.473Glecaprevir
CAS:Controlled Product<p>Applications Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.<br>References Kwo, P., et. al.: J. Hepatol, 67, 263 (2017)Gane, E., et. al.: N. Engl. J. Med, 377, 1448 (2017)<br></p>Formula:C38H46F4N6O9SColor and Shape:NeatMolecular weight:838.864-Methylbenzenesulfonic Acid Monohydrate
CAS:Controlled Product<p>Impurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F<br>Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);<br></p>Formula:C7H8O3S·H2OColor and Shape:WhiteMolecular weight:190.223,3',5'-Triiodo-L-thyronine
CAS:Formula:C15H12I3NO4Color and Shape:Light Beige To GreyMolecular weight:650.97(S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic Acid
CAS:Controlled Product<p>Applications (S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic Acid is an intermediate for Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C31H42N4O6Color and Shape:NeatMolecular weight:566.69Dihydro Cyclosporin A
CAS:Controlled Product<p>Applications A Cyclosporin A (C988900) analog, an immunosuppressant.<br>References Emmer, G., et al.: J. Med. Chem., 37, 1918 (1994), High, K., et al.: J. Biol. Chem., 269, 9105 (1994),<br></p>Formula:C62H113N11O12Color and Shape:WhiteMolecular weight:1204.63N-Acetyl-L-carnosine
CAS:Controlled Product<p>Applications Used in the treatment of cataracts and in the treatment of UV-induced immunosuppression. May act with with lipoic acid (L468725) to reverse age-related metabolic decline and also the indicies of oxidative stress.<br>References Babizhayev, M., et al.: J. Pharmacol. Toxicol., 1, 201 (2006), Min, J., et al.: J. Neurosci. Res., 86, 2984 (2008), Babizhayev, M., et al.: J. Drug Target., 17, 36 (2009); Hagen et. al, PNAS 99: 1870 (2002); Liu et. al, PNAS 99, 2356 (2002)<br></p>Formula:C11H16N4O4Color and Shape:Off-WhiteMolecular weight:268.276-Perdeoxy-6-perchloro-γ-cyclodextrin, >90%
CAS:Formula:C48H72Cl8O32Purity:>90%Color and Shape:NeatMolecular weight:1444.69(R)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium Chloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (R)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride is an important co-factor of mammalian mitochondrial energy metabolism. It is also a good active ingredient for dry-skin.<br>References Geier, David A., et al.: Neurochem. Res., 38(11), 2336-2341 (2013);Tanno, Osamu, et al.: Fragrance J., 33(8), 82-85 (2005);<br></p>Formula:C7H16NO3·ClColor and Shape:White To Off-WhiteMolecular weight:197.660N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
CAS:<p>Impurity Bortezomib USP Impurity B<br>Applications N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.<br>References Pekol, T., et al.: Drug. Meta. Disp., 33, 771 (2005); Hsieh, F.Y., et al.: J. Pharma. Biomed. Anal., 49, 115 (2009);<br></p>Formula:C14H14N4O2Color and Shape:NeatMolecular weight:270.29Tabimorelin
CAS:Controlled Product<p>Applications NN703 (Tabimorelin) is an orally active growth hormone (GH) secretagogue intended for use as an alternative to daily injections of GH. In vitro studies in human liver microsomes have indicated that NN703 is a mechanism-based inhibitor of CYP3A4.<br>References Fabre, G., et al.: Biochem. Pharmacol., 37, 4389 (1988), Thummel, K., et al.: Clin. Pharmacol. Ther., 59, 491 (1996), Yu, D., et al.: J. Clin. Pharmacol., 39, 1203 (1999),<br></p>Formula:C32H40N4O3Color and Shape:NeatMolecular weight:528.68Bivalirudin Trifluoroacetic Acid Salt
CAS:<p>Applications Bivalirudin Trifluoroacetic Acid Salt is an anticoagulant drug that is a direct thrombin inhibitor. It is used for treatment of acute coronary syndromes, and is a safer alternative to heparin due to lower rates of bleeding as an adverse effect of anticoagulant in patients.<br>References Stone, G., et al.: N. Engl. J. Med, 355, 2203 (2006); Stone, G., et al.: N Engl J Med, 358, 2218 (2008);<br></p>Formula:C98H138N24O33·(C2HF3O2)xColor and Shape:NeatMolecular weight:2180.2911402N,N-Dimethyl-4-hydroxymethoxy Clomiphene (~90%, contains ~10% Z-isomer)
CAS:Controlled ProductFormula:C25H26ClNO3Color and Shape:NeatMolecular weight:423.93N-Nitroso Lisinopril
CAS:Formula:C21H30N4O6Color and Shape:White To Light YellowMolecular weight:434.486Perfluorophenol
CAS:Controlled Product<p>Applications Perfluorophenol is used in the synthesis of PGA-films as biodegradable polymers. It also participates in the synthesis of tripod macrocyclic Gd(III) chelates for cancer molecular MRI.<br>References Lee, K. et al.: Langmuir., 20, 2531 (2004); Zhou, Z. et al.: Biomater., 34, 7683 (2013);<br></p>Formula:C6HF5OColor and Shape:NeatMolecular weight:184.06Bestatin
CAS:<p>Bestatin (Ubenimex) competitively inhibits many aminopeptidases. Bestatin is a microbial metabolite and dipeptide with immunomodulatory and antitumor effects.</p>Formula:C16H24N2O4Purity:98% - 99.63%Color and Shape:White Crystalline PowderMolecular weight:308.37L-Carnitine-L-tartrate
CAS:Controlled Product<p>Applications L-Carnitine-L-tartrate (cas# 36687-82-8) is a useful research chemical.<br></p>Formula:C7H16NO3·C4H4O6Color and Shape:White To Off-WhiteMolecular weight:472.48(R)-Hydroxy Des(boric Acid) Bortezomib
CAS:Controlled Product<p>Impurity Bortezomib USP Impurity I<br>Applications (R)-Hydroxy Des(boric acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C. et al.: Chem. and Eng. News, 87, 41 (2009)<br></p>Formula:C19H24N4O3Color and Shape:NeatMolecular weight:356.42Bortezomib
CAS:Controlled Product<p>Stability Hygroscopic and Moisture Sensitive<br>Applications Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);<br></p>Formula:C19H25BN4O4Color and Shape:White To Off-WhiteMolecular weight:384.24Voclosporin-d4
CAS:Controlled Product<p>Applications Labelled Voclosporin (V678500). A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile, a strong correlation between pharmacokinetic and pharmacodynamic response, and a wide therapeutic window. Immunosuppressant.<br>References Aspeslet, L., et al.: Transplant Proc., 33, 1048 (2001), Cho, M., et al.: Arthritis Rheum., 46, 1202 (2002), Staatz, C., et al.: Clin. Pharmacokinet., 43, 623 (2004),<br></p>Formula:C63H107D4N11O12Color and Shape:NeatMolecular weight:1218.65(2S,4S)-Sacubitril
CAS:<p>Stability Moisture Sensitive<br>Applications (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Formula:C24H29NO5Color and Shape:NeatMolecular weight:411.49N-Formyl Thyroxine
CAS:Controlled Product<p>Impurity Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)<br>Applications N-Formyl Thyroxine (Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)) is a thyroxine derivative which showed less thyroid activity than Thyroxine Sodium (T425601).<br>References Basil, B., et al.: Br. J. Pharmacol. Chemother., 5, 315 (1950),<br></p>Formula:C16H11I4NO5Color and Shape:NeatMolecular weight:804.88Teduglutide-d8 TFA salt x hydrate (Leu-methyl-d3+Phe-d5)
CAS:Controlled Product<p>Applications Teduglutide-d8 TFA salt x hydrate (Leu-methyl-d3+Phe-d5) is an isotopically labelled form of Teduglutide (T013795), which is glucagon-like peptide-2 (GLP-2) analogue that is used for the treatment of short bowel syndrome.<br>References Jeppesen, P., et al.: Gut, 54, 1224 (2005)<br>Chemical Name: Jeppesen, P., et al.: Gut, 54, 1224 (2005)<br></p>Formula:C164H244D8N44O55S•C2HF3O2•x(H2O)Color and Shape:NeatMolecular weight:3760.081140218Cyclosporin B
CAS:<p>Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Formula:C61H109N11O12Purity:>80%Color and Shape:NeatMolecular weight:1188.58N-Acetyl-L-methionine
CAS:Controlled Product<p>Applications N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold-stored platelets.<br>References D’Alessandro, A., et al.: Transfusion (Malden, MA, US), 60, S96 (2020)<br></p>Formula:C7H13NO3SColor and Shape:NeatMolecular weight:191.00L-Prolinamide
CAS:<p>Applications Proline based organocatalyst.<br>References Alberg, D., et al.: Bioorg. Med. Chem. Lett., 19, 3888 (2009), Huang, X., et al.: J. Phys. Chem., 114, 1068 (2010),<br></p>Formula:C5H10N2OColor and Shape:White SolidMolecular weight:114.146(4R)-1-Methyl-4-propyl-L-proline Hydrochloride
CAS:Controlled Product<p>Applications Proline derivative, and an intermediate in the production of biosynthetic antibiotics.<br></p>Formula:C9H17NO2·ClHColor and Shape:NeatMolecular weight:207.70N-Acetyl-DL-methionine
CAS:Controlled Product<p>Applications C7H13NO3S (cas# 1115-47-5) is a useful research chemical.<br></p>Formula:C7H13NO3SColor and Shape:NeatMolecular weight:191.25TD-165
CAS:<p>TD-165, a PROTAC-based cereblon (CRBN) degrader, consists of a cereblon (CRBN) ligand-binding group, a linker, and a von Hippel-Landau (VHL) binding group[1].</p>Formula:C46H59N7O8SPurity:99.24%Color and Shape:SolidMolecular weight:870.07MK 677
CAS:<p>Applications MK-677 is a potent, non-peptide ghrelin receptor agonist.<br>References Kirstie, A., et al.: Mol. Pharmacol., 76, 802 (2009); Birgitte, H. et al.: Mol. Pharmacol., 75, 44 (2009)<br></p>Formula:C27H36N4O5S·CH4SO3Color and Shape:NeatMolecular weight:624.80Cyclosporin H
CAS:<p>Applications Cyclosporin is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Formula:C62H111N11O12Color and Shape:NeatMolecular weight:1202.61Boceprevir (>90%)
CAS:Controlled ProductFormula:C27H45N5O5Purity:>90%Color and Shape:NeatMolecular weight:519.684-(Phenylamino]-1-benzyl-4-piperidinecarboxylic Acid Methyl Ester
CAS:Controlled Product<p>Applications Remifentanil derivative.<br>References James, M.K., et al.: J. Pharmacol. Exp. Ther., 259, 712 (1991), Hoffman, W.E., et al.: Anesthesiology, 79, 107 (1993), Selinger, K., et al.: J. Pharm. Biomed. Anal., 12, 243 (1994), Richardson, T.D., et al.: Expert Opin. Drug Saf., 4, 643 (2005),<br></p>Formula:C20H24N2O2Color and Shape:NeatMolecular weight:324.4168Carfilzomib (2R,4S)-Diol
CAS:Controlled Product<p>Applications Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C40H59N5O8Color and Shape:NeatMolecular weight:737.93L-Valine-13C5,15N
CAS:Controlled Product<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Formula:C5H1115NO2Color and Shape:NeatMolecular weight:123.1N-Nitroso-D-proline
CAS:Controlled Product<p>Applications A nitrosoamino acid with oncogenic activity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg.<br>References Nagasawa, H.T., et al.: J. Med. Chem., 16 (5), 583-585 (1973)<br></p>Formula:C5H8N2O3Color and Shape:NeatMolecular weight:144.13Cyclosporin C
CAS:Controlled Product<p>Applications A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Formula:C62H111N11O13Purity:>80%Color and Shape:NeatMolecular weight:1218.61Bortezomib Trimer
CAS:Controlled Product<p>Applications Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Formula:C57H69B3N12O9Color and Shape:NeatMolecular weight:1098.666Methyltetrazine-Amine
CAS:<p>Methyltetrazine-Amine is a methyl-substituted tetrazine amine used in the synthesis of PROTAC molecules.</p>Formula:C10H11N5Purity:97.59%Color and Shape:Pink SolidMolecular weight:201.23Sacubitril-d4
CAS:Controlled Product<p>Applications Isotope labelled Sacubitril is an antihypertensive drug used in combination with Valsartan (V095750). The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Formula:C242H4H25NO5Color and Shape:Light YellowMolecular weight:415.521,2-Bismethylphenidate (Mixture of Diastereomers)
Controlled Product<p>Applications 1,2-Bismethylphenidate is an impurity of methylphenidate (M325880), an CNS stimulant.<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Formula:C23H27NO4Color and Shape:NeatMolecular weight:381.46(2S,4R)-Sacubitril
CAS:Controlled Product<p>Stability Temperature Sensitive<br>Applications (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Formula:C24H29NO5Color and Shape:Colourless To Off-WhiteMolecular weight:411.49Cyclosporin AM 1 (>80%)
CAS:Controlled Product<p>Applications A cyclosporine metabolite specifically inhibits growth of renal cells in culture.<br>References Schultz, J.C.; et al.: Biochem. Pharma., 42, 1403 (1991), Johnson, B., et al.: Drug Metab. Dispos., 34, 556 (2006), Westley, I.S., Drug Metab. Dispos., 36, 46 (2008).<br></p>Formula:C62H111N11O13Purity:>80%Color and Shape:NeatMolecular weight:1218.615-Oxo-DL-proline-d5
CAS:Controlled Product<p>Applications 5-Oxo-DL-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>Formula:C52H5H2NO3Color and Shape:NeatMolecular weight:134.143,3’,5-Triiodo-L-thyronine
CAS:Controlled ProductFormula:C15H12I3NO4Color and Shape:White To Off-WhiteMolecular weight:650.973,5,3',5'-Tetraiodo Thyroacetamide
CAS:Controlled Product<p>Impurity Levothyroxine Acetamide Impurity<br>Applications 3,5,3',5'-Tetraiodo Thyroacetamide is a thyroid hormone analogue, a Thyroxine (T425600) impurity.<br>References Andre, M., et al.: J. Chromatogr., 741, 146 (1996),<br></p>Formula:C14H9I4NO3Color and Shape:Light Orange Colour To Light BrownMolecular weight:746.84N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Lisinopryl impurity.<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Cao, X.J., et al.: J. Pharm. Biomed. Anal., 39, 39 (2005),<br></p>Formula:C16H24N2O4Color and Shape:White To Light BeigeMolecular weight:308.37Methionine
CAS:<p>Methionine (D-Methionine) (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor</p>Formula:C5H11NO2SPurity:99.13% - 99.62%Color and Shape:SolidMolecular weight:149.21L-Methionine [R,S]-Sulfoximine
CAS:Controlled Product<p>Applications Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.<br>References Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979), Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)<br></p>Formula:C5H12N2O3SColor and Shape:NeatMolecular weight:180.23N-Pyrazinylcarbonyl-L-phenylalanine
CAS:Controlled Product<p>Applications Used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Formula:C14H13N3O3Color and Shape:WhiteMolecular weight:271.27[Des-Thr-ol8]-[D-Cys7]-Octreotide TFA
CAS:Controlled ProductFormula:C45H57N9O9S2•x(C2HF3O2)Color and Shape:NeatMolecular weight:932.12114023,3’,5-Triiodo-D-thyronine
CAS:Controlled Product<p>Applications 3,3’,5-Triiodo-D-thyronine is a structural analogue o the thyroid homonef Thyroxine (T425600). 3,3’,5-Triiodo-D-thyronine has been shown to reduce cholesterol in blood serum.<br>References Mintz, D.O., et. al.: New Engl. J. Med., 266, 808 (1962)<br></p>Formula:C15H12I3NO4Color and Shape:Off-White To Light BrownMolecular weight:650.97L-Threonine
CAS:Controlled Product<p>Applications L-enantiomer of Threonine. An essential amino acid for human development; last of the common amino acids to be discovered. Identified in oat protein.<br>References LeMaster, D.M., et al.: J. Biol. Chem., 257, 1224 (1982), Ballevre, O., et al.: Anal. Biochem., 193, 212 (1991), Roufs, J.B., et al.: Med. Hypotheses, 34, 20 (1991), Blin, O., et al.: J. Neurol., 239, 79 (1992),<br></p>Formula:C4H9NO3Color and Shape:NeatMolecular weight:119.12(S)-Lisinopril Dimer
CAS:Controlled Product<p>Applications (S)-Lisinopril (L468985) impurity. Lisinopril Impurity G (Dimer Impurity)<br></p>Formula:C42H60N6O9Color and Shape:WhiteMolecular weight:792.96Dl-valine
CAS:Controlled Product<p>Applications Dl-valine<br></p>Formula:C5H11NO2Color and Shape:NeatMolecular weight:117.15Methyl Benzenesulfonate
CAS:Controlled Product<p>Applications A sulfonate ester as potential genotoxic impurity in drug substances. It may exert genotoxic effects in bacterial and mammalian cell systems.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eder, E., et al.: Xenobiotica, 12, 831 (1982), Li, W., et al.: J. Chromatogr., 1046, 297 (2004), Glowienke, S., et al.: Mutat. Res., 581, 23 (2005), Colon, I., et al.: J. Pharm. Biomed. Anal., 39, 477 (2005),<br></p>Formula:C7H8O3SColor and Shape:ColourlessMolecular weight:172.2Daptomycin
CAS:<p>Applications Daptomycin is a Cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.<br>References Allen, N.E., et al.: Antimicrob. Agents Chemother., 31, 1093 (1987), Tully, F.P., et al.: Expert Opin. Invest. Drugs, 8, 1223 (1999),<br></p>Formula:C72H101N17O26Color and Shape:Light YellowMolecular weight:1620.67Vasopressin Acetic Acid Salt
CAS:Controlled Product<p>Applications Vasopressin Acetic Acid Salt is an acidic salt of Vasopressin (V991530), an antidiurectic hormone.<br>References Tokushige, S., et al.: Internal Medicine, 55, 1199 (2016)<br></p>Formula:C46H65N15O12S2•(C2H4O2)Color and Shape:NeatMolecular weight:1084.236005trans-4-Hydroxy-L-proline
CAS:Controlled Product<p>Applications A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.<br>References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001);<br></p>Formula:C5H9NO3Color and Shape:NeatMolecular weight:131.13Carbetocin
CAS:<p>Applications An obstetric drug used to control postpartum hemorrhaging.<br>References Sanz-Nebot, V., et al.: Anal. Bioanal. Chem., 377, 306 (2003), Gimpl, G., et al.: Eur. J. Pharmacol., 510, 9 (2005), Handler, J., et al.: Theriogenol., 66, 1397 (2006), Klenerova, V., et al.: J. Physiol. Pharmacol., 60, 57 (2009),<br></p>Formula:C45H69N11O12SColor and Shape:NeatMolecular weight:988.16(±)-Methionine
CAS:<p>Applications (±)-Methionine is an essential amino acid involved in various biochemical processes in humans and mammals. Also in poultry meal as a source of nutrition.<br>References Martin-Venegas, R. et al.: Food Chem., 141, 1702 (2013); Austic, R. et al.: J. Agri. Food Chem., 61, 7341 (2013); Yan, L. et al.: J. Anim. Phys Anim Nutr., 97, 457 (2013);<br></p>Formula:C5H11NO2SColor and Shape:WhiteMolecular weight:149.21N-des-succinyl-Sacubitril hydrochloride
CAS:Controlled Product<p>Applications (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.<br>References Liu, M., et al.: Faming Zhuanli Shenqing. CN 105168205 A 20151223. Dec 23, 2015; Wang, Z.: PCT Int. Appl. WO 2015154673 A1 20151015. Oct 15, 2015<br></p>Formula:C20H25NO2·HClColor and Shape:NeatMolecular weight:384.34Eptifibatide
CAS:Controlled Product<p>Applications An arginine-glycine-aspartate-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events.<br>References Pathak, A., et al.: Cardiovas. Diabetol., 7 (2008), Hantgan, R., et al.: Biochem., 48, 8355 (2009), Giugliano, R., et al.: New Eng. J. Med., 360, 2176 (2009),<br></p>Formula:C35H49N11O9S2Color and Shape:Off White SolidMolecular weight:831.96Carfilzomib (2R,4R)-Diol
Controlled Product<p>Applications Carfilzomib (2R,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C40H59N5O8Color and Shape:NeatMolecular weight:737.93Carfilzomib
CAS:Controlled Product<p>Applications Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C40H57N5O7Color and Shape:White To Off-WhiteMolecular weight:719.91Oxytocin-d5 Trifluoroacetate
CAS:Controlled Product<p>Applications Labelled Oxytocin. The principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland.<br>References Pierce, et al.: J. Biol. Chem., 199, 929 (1952), Tuppy, et al.: Biochem. Biophys. Acta, 11, 449 (1953), Cash, et al.: J. Med. Pharm. Chem., 5, 413 (1962), Nachtmann, F., et al.: Anal. Profiles Drug Subs., 10, 563 (1981),<br></p>Formula:C45H62D5F3N12O14S2Color and Shape:White To Off-WhiteMolecular weight:1126.24Desethyl Sacubitril-d4
CAS:Controlled ProductFormula:C22H21D4NO5Color and Shape:NeatMolecular weight:387.46
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