Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Found 79347 products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
CAS:<p>Applications 4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H17Cl2N3O5SColor and Shape:NeatMolecular weight:470.3310-Hydroxy Warfarin(Mixture of Diastereomers)
CAS:Controlled ProductFormula:C19H16O5Color and Shape:NeatMolecular weight:324.33(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
CAS:Controlled Product<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate used to prepare trans-2-arylcyclopropylamines as potent and selective dipeptidyl peptidase IV inhibitors.<br>References Tsai, T., et al.: Bioorg. Med. Chem., 17, 2388 (2009)<br></p>Formula:C9H9F2N·HClColor and Shape:Off White SolidMolecular weight:205.632Perindoprilat Lactam A
CAS:<p>Impurity Perindopril EP Impurity C<br>Applications Perindoprilat Lactam A (Perindopril EP Impurity C) is the active metabolite of Perindopril (P287500) in plasma and urine.<br>References Hillaert, S., et al.: J. Pharm. Biomed. Anal., 25, 775 (2001), Ozoemena, K., et al.: Talanta, 62, 681 (2004),<br></p>Formula:C17H26N2O4Color and Shape:White To BeigeMolecular weight:322.40Risperidone Related Compounds Mixture
Formula:C23H27FN4O2C23H28FIN4O2C23H28F2N4O2C23H27FN4O3Molecular weight:410.48 : 538.41 : 430.49: 426.48Ivermectin B1 Monosaccharide
CAS:Controlled Product<p>Applications Ivermectin B1 Mono-sugar Derivative is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. An invitro inhibitor of SARS-CoV-2/ Covid-19.<br>References Campbell, W., et al.: Science, 221, 823 (1983); Glaziou, P., et al.: Trop. Med. Parasitol., 45, 253 (1994); Meinking, T., et al.: New Engl. J. Med., 333, 26 (1995); Caly, L., et al.: Antivir. Res., 178<br></p>Formula:C41H62O11Color and Shape:NeatMolecular weight:730.92Rivaroxaban Pseudodimer
CAS:<p>Applications Rivaroxaban Pseudodimer is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C38H36Cl2N6O10S2Color and Shape:NeatMolecular weight:871.762-Amino-5-(trifluoromethoxy)phenyl Thiocyanate
CAS:<p>Applications An impurity of Riluzole (R510000).<br></p>Formula:C8H5F3N2OSColor and Shape:NeatMolecular weight:234.20Diclofenac Acyl-β-D-glucuronide
CAS:Controlled Product<p>Applications A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.<br>References Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004)<br></p>Formula:C20H19Cl2NO8Color and Shape:NeatMolecular weight:472.27Trimethylamine Monohydrochloride
CAS:Controlled ProductFormula:C3H9N·ClHColor and Shape:NeatMolecular weight:95.5712Eltrombopag Ethyl Ester
Controlled Product<p>Applications Eltrombopag Ethyl Ester, is a metabolite of Eltrombopag (E508000), which is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.<br>References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),<br></p>Formula:C27H26N4O4Color and Shape:NeatMolecular weight:470.522-[(2,6-Dichlorophenyl)amino]benzaldehyde (Diclofenac impurity)
CAS:<p>Impurity Diclofenac EP Impurity B<br>Applications 2-[(2,6-Dichlorophenyl)amino]benzaldehyde (Diclofenac EP Impurity B) is an impurity of Diclofenac (D436450).<br>References Brogden, R., et al.: Drugs, 20, 24 (1980), Orienti, I., et al.: Eur. J. Pharm. Biopharm., 37, 110 (1991), Sagara, K., et al.: Chem. Pharm. Bull., 40, 3303 (1992), Connors, K., et al.: J. Pharm. Sci., 84, 843 (1995),<br></p>Formula:C13H9Cl2NOColor and Shape:YellowMolecular weight:266.123’-Hydroxy Warfarin
CAS:Controlled Product<p>Applications A new metabolite of Warfarin using Cunninghamella elegans.<br>References Wong, Y. W., et al.: J. Pharma. Sci., 80, 305 (1991)<br></p>Formula:C19H16O5Color and Shape:NeatMolecular weight:324.33Lesinurad
CAS:Controlled Product<p>Applications Lesinurad is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.<br>References Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WO 2011159732 A1 20111222 (2011); Crittenden, D. B. et al.: Clinical Investigation 1, 1563-1575 (2011)<br></p>Formula:C17H14BrN3O2SColor and Shape:NeatMolecular weight:404.28
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