APIs for research and impurities

<p>2-Methoxy-5-methyL-N,N-bis(1-methyLethyl)-gamma-phenyLbenzenepropanamine fumarate (DMXBPC) is an analgesic that has been shown to be a potent inhibitor of the cytosolic phospholipase A2 and is also cytotoxic. DMXBPC has significant cholinergic activity and can inhibit the synthesis of prostaglandins in the prostate gland. DMXBPC binds to the pyridine ring of DOPA and inhibits its conversion to dopamine. The enantiomers of DMXBPC have different effects on inhibition of phospholipase A2, with the (+) form being more potent than the (-) form. This is due to the fact that (+)DMXBPC binds more tightly to the enzyme than (-)DMXBPC does.</p>

<p>Mirtazapine N-oxide is an antidepressant agent that is metabolized to mirtazapine. Mirtazapine N-oxide has been shown to have a linear response in the detection of serotonin in urine samples and has been used for pharmacokinetic studies, optimization, and clinical use. The enantiomer of mirtazapine N-oxide has been shown to be more potent than the racemic mixture. The drug is excreted unchanged into the urine with a half-life of 2 hours. Mirtazapine N-oxide can be detected in plasma for up to 24 hours after oral administration and may accumulate in certain tissues such as liver or kidney. This drug has also been shown to cause death in mice at very high doses.</p>

<p>Mycophenolate mofetil N-oxide is a metabolite that is formed during the synthesis of mycophenolic acid, a drug used for the treatment of autoimmune disorders such as rheumatoid arthritis. Mycophenolate mofetil N-oxide is a white solid with an mp of about 155°C. It has been shown to inhibit protein synthesis in cells, and has been investigated for its potential use in cancer therapy.</p>

<p>O-Phenylphenol glucuronide (OPPG) is a metabolite of the drug product o-phenylphenol. It is used as an analytical standard and impurity standard for HPLC, and is also used in drug development. OPPG has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. It is a natural metabolite that can be found in human urine and bile, but it can also be synthesized through chemical reactions. OPPG has been shown to have niche applications in metabolism studies and drug development, and has been shown to act as an anti-inflammatory agent.</p>

<p>1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyl-1-propanone is a metabolite that is formed from the drug product. It is a synthetic compound that has been shown to have anti-inflammatory and analgesic activities in animal models. 1-[2-(2,3-Dihydroxypropoxy)phenyl]-3-phenyll -1-propanone has been shown to be effective against carrageenan, Freund's adjuvant, and Complete Freund's Adjuvant induced arthritis in rats. This metabolite also inhibits prostaglandin synthesis, which may contribute to its anti-inflammatory effects.</p>

<p>Please enquire for more information about BLM-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Desphenol 1-hydroxyethyl cefoperazone furolactone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-Acetyl-o-tert-butoxycarbonyl serotonin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Hexacosene is a medicinal compound with potential anticancer properties. It has been shown to inhibit the activity of certain kinases, which are enzymes involved in cell signaling and regulation. This inhibition leads to increased apoptosis, or programmed cell death, in cancer cells. 1-Hexacosene has also demonstrated inhibitory effects on tumor growth in Chinese hamsters. In addition, this compound has been found in human urine and may have potential as a biomarker for cancer diagnosis or monitoring. Further research is needed to fully understand the therapeutic potential of 1-Hexacosene as an inhibitor of protein kinases in cancer treatment.</p>

<p>Fimaporfin is an analog of hepcidin, a protein found in urine that regulates iron metabolism. It is a kinase inhibitor that induces apoptosis in cancer cells. Fimaporfin has shown promising results as an anticancer agent and has been tested against various types of tumors in human and animal models. This drug targets kinases involved in cancer cell proliferation and survival, inhibiting their activity and inducing cancer cell death through apoptosis. Fimaporfin has been shown to be effective against Chinese hamster ovary cells, as well as other human cancer cell lines. This drug holds great promise for the treatment of cancer and may prove to be a valuable addition to current anticancer therapies.</p>

<p>Ceftazidime t-butyl ester is a prodrug of ceftazidime. It is a crystalline, stable form of the drug that can be dissolved in an organic solvent. Ceftazidime t-butyl ester has an average UV detection wavelength with a linear range of 200-600 nm and can be detected at a wavelength of 220 nm. This drug is used to treat infections caused by bacteria, including those that are resistant to other antibiotics, such as penicillin or ampicillin. Ceftazidime t-butyl ester has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.</p>

<p>(2R)-3-Hydroxyisovaleroyl-d3 carnitine is a drug product that is custom synthesized for research and development. It has a purity of &gt;90%. This product can be used in metabolism studies, natural products, drug development, pharmacopoeia, or as an analytical reference standard. The CAS number for this product is 1058636-00-2. (2R)-3-Hydroxyisovaleroyl-d3 carnitine may also contain impurities of 0.05%. The molecular weight for this compound is 266.37 g/mol and the chemical formula is C5H11NO4.</p>

<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>

<p>4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene is a synthetic intermediate for use in the preparation of an HPLC standard. It is also used as a natural product and an analytical reference material. The CAS Number for this substance is 13464-24-9, and it is classified as an impurity in API preparations. 4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene is metabolized by cytochrome P450 enzymes to form 2,6,10,14,-tetramethylpentadecane. This compound has been found to have antiinflammatory activity.</p>

<p>Please enquire for more information about Physcion-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.</p>

<p>Please enquire for more information about (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Cefazolinamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(1aS,4S,6aR,7aS)-6-Amino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-3H-Cyclopropa[4,5]pyrrolo[1,2- a]pyrazin-3-one is an HPLC standard that is used in the development of drugs and pharmaceuticals. It is an impurity found in API's and is also known as a metabolite. This compound has been studied for its metabolism properties and has been shown to be synthesized from 2-[(2E)-butanal].</p>

<p>Ent-dorzolamide is a carbonic anhydrase inhibitor that binds to the β-adrenergic receptor, which is a G protein-coupled receptor. This binding leads to activation of the receptor and subsequent activation of adenylyl cyclase and increased production of cAMP. It has been shown to have insulin sensitizing effects in animal models. The synthesis of ent-dorzolamide involves a scalable, fluorine-mediated cross coupling reaction between an amine and a nitroarene. Ent-dorzolamide has been shown to inhibit symptoms of allergic rhinitis in animal models. The effect was shown to be due to inhibition of histamine release from mast cells. Ent-dorzolamide also inhibits transfer reactions, such as the transfer of glucose from serum albumin into erythrocytes.</p>