APIs for research and impurities

<p>Alverine EP Impurity E is a nitrogen containing compound with the molecular formula C9H10N. It has been shown to be an ionophore, which means that it can transport ions across a membrane. Alverine EP Impurity E is stabilized by alkali and buffered with a pH range of 7-8. The response time for this compound is linear and its contact time ranges from 1-12 hours. This impurity has a phenyl group and a ph range of 6-7. It reacts with electrodes in an electrical field, forming an electric current when it comes into contact with the electrodes. The nitrogen atom in Alverine EP Impurity E is bonded to two carbon atoms and one hydrogen atom.</p>

<p>o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.</p>

<p>(R)-N4-(3-Chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine is a drug product that is custom synthesized. It has an analytical purity of 99.2% and a natural purity of 97%. Metabolism studies have been performed with this substance. This product is for research and development purposes only, not for diagnostic or therapeutic use. (R)-N4-(3-Chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine is manufactured in accordance with the pharmacopoeia and can be used as a metabolite standard or impurity standard.</p>

<p>Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.</p>

<p>Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.</p>

<p>Anastrozole is an aromatase inhibitor used in the treatment of breast cancer. It is a synthetic drug and impurity standard for HPLC analysis, pharmacopoeia monograph, and synthetic drug development. This product is a mixture of two stereoisomers - the active form, 4-hydroxyanastrozole (4HA), and the inactive form, 4-oxo-anastrozole (4OA). The purity of this product is &gt;99% with a melting point of 130°C.</p>

<p>Zm 306416 hydrochloride is a new synthetic compound with antimicrobial activities. It has been shown to be active against gram-positive bacteria, gram-negative bacteria, and fungi. Zm 306416 hydrochloride can also protect mice from carbon tetrachloride-induced liver damage by reducing serum bilirubin levels and inhibiting lipid peroxidation. This compound can also be used as a photocatalyst in organic synthesis.</p>

<p>1,4-Bis(2,3,4-trimethoxybenzyl)piperazine (1,4BTMP) is a piperazine derivative that has been shown to have inotropic properties. 1,4BTMP appears to increase the force of contraction of the heart muscle by increasing intracellular calcium levels. This drug may also be useful in the treatment of ventricular fibrillation and other arrhythmias. It has been shown that 1,4BTMP protects against lipid peroxidation induced by hydrogen chloride and hydrochloric acid in isolated rat hearts. In addition, this compound has been shown to inhibit creatine kinase activity and reduce lipid peroxide formation.</p>

<p>(5E)-Calcipotriene is a synthetic, natural, and analytical chemical. It is a white to off-white powder with a melting point of about 122 °C. (5E)-Calcipotriene has been used as an analytical standard for HPLC and as an impurity in the synthesis of calcitriol. The International Union of Pure and Applied Chemistry (IUPAC) name for this compound is 5Z,7Z,11Z,15Z-eicosapentaenoic acid. It can also be found in the form of 5Z,8Z,11Z,14E-eicosapentaenoic acid.</p>

<p>Sulfo EGS is a potent analog that has shown promising anticancer activity in various human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. Sulfo EGS has been found to be particularly effective against Chinese hamster ovary cells and tumor cells from medicinal plants. This inhibitor also shows potential for use in the development of kinase inhibitors for cancer therapy. In addition, Sulfo EGS is commonly used as a cross-linking reagent to covalently link proteins or protein complexes in urine or other biological samples for further analysis. Overall, Sulfo EGS is an important tool for cancer research and drug development.</p>

<p>Please enquire for more information about 1-[(4-Chlorophenyl)phenylmethyl]-4-(phenylsulfonyl)piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Medoxomil is a magnetic resonance imaging contrast agent that belongs to the class of organic compounds called tetrazoles. Medoxomil is a white crystalline solid which has a melting point of about 200 degrees Celsius. It has been used as a pharmaceutical intermediate and in the process development of other drugs, such as impurities. Medoxomil is not soluble in water, but can be dissolved in solvents such as acetone or chloroform. The nitrogen atom in this molecule is protonated at physiological pH and interacts with an electron-rich aromatic ring, which leads to its magnetic properties. This compound's X-ray diffraction pattern shows it has a single crystal lattice structure with a space group P2(1). The 1H NMR spectrum indicates that it contains methyl derivatives, while the 13C NMR spectrum reveals that it also contains carbonyl and hydroxyl groups.</p>

<p>Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.</p>

<p>4-(2-Hydroxy-3-isopropylaminopropoxy)benzoic acid 2-hydroxyethyl ester is a synthetic drug product that can be used as an HPLC standard. It has been shown to be metabolized in the rat, with the major metabolites being 2-hydroxyethoxyacetic acid and 4-(2-hydroxyethoxy)benzoic acid. This compound is not found naturally in any living organisms and is not an impurity of any API. The purity of this compound is &gt;98%.</p>

<p>7-O-(Triethylsilyl) paclitaxel is a synthetic Taxol analog. It is manufactured by custom synthesis and purified by HPLC to be used as an analytical standard for the determination of natural Taxol impurities in drug products.</p>

<p>(2E,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-2,6-dimethyl-1-naphthalenyl]-5-hydroxy-2-heptenoic acid sodium salt is a synthetic drug product. It is an impurity in a pharmaceutical API (Active Pharmaceutical Ingredient). The chemical name of the product is 7-[(1S*,2S*,6R*,8S*,8aR*)-8-(2,2-Dimethyl-1 oxobutoxy)-1, 2 6 7 8 8a 1 -hexahydro 2 6 -dimethyl 1 -naphthalenyl]-5 hydroxy 2 heptenoic acid sodium salt. It has the following CAS Number: 39</p>

<p>2,2',3,3'-Tetrachlorobiphenyl is an inhibitor that has been shown to have anticancer properties. It inhibits the growth of tumor cells by blocking the activity of protein kinases, which are enzymes that regulate cell division and proliferation. This compound has been tested in Chinese hamster ovary cells and has been found to induce apoptosis in cancer cells. Additionally, 2,2',3,3'-Tetrachlorobiphenyl has analog inhibitors that have been tested in human urine samples and have shown potential as anticancer agents. These analogs inhibit cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle. The inhibition of CDKs leads to the suppression of cancer cell growth and division, making this compound a promising candidate for future cancer treatments.</p>

<p>3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione is a research and development impurity standard. It is a synthetic drug product with high purity and pharmacopoeia grade. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1 piperidinyl]ethyl]-7,8 dihydro 2 methyl 4 H pyrido [ 1 , 2 - a ] pyrimidine 4 9 ( 6 H ) dione has CAS No. 118951665 1 and is an analytical standard for HPLC analysis. 3-[2-[4-(6 Fluoro 1 , 2 benzisox</p>

<p>Biphenyl-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester is a research and development impurity standard. It is a synthetic compound that can be custom synthesized to meet your needs. The product is available in high purity and pharmacopoeia grade. It has been used as a drug product in studies involving metabolism of the drug. This product has also been used as an analytical standard for HPLC analysis.</p>

<p>Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a synthetic compound that has been used as an impurity standard for the drug product and as a metabolite in pharmacopoeia. Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is also used in research and development, including drug metabolism studies. Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a high purity and custom synthesis that is used as an analytical standard for HPLC.</p>