APIs for research and impurities

<p>Please enquire for more information about 1-(1-Cyclohexen-1-yl)-cyclohexanecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Haloperidol octanoate is a synthetic, long-acting neuroleptic that is used to treat schizophrenia and other psychotic disorders. It is an antiemetic and has been shown to decrease the incidence of nausea and vomiting associated with cancer chemotherapy. Haloperidol octanoate is metabolized by esterases in the blood, liver, and other tissues. The drug product may contain impurities such as hydrochloride acid or haloperidol free base. Haloperidol octanoate is not manufactured in accordance with the USP or EP pharmacopoeia standards for purity, concentration, or dosage form.</p>

<p>Please enquire for more information about Meclizine ortho chloro isomer bishydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PBDE 202 is a potent inhibitor of kinases, specifically protein kinases. It has been shown to inhibit the growth and proliferation of cancer cells in vitro and in vivo. PBDE 202 is an analog of other medicinal inhibitors and has been studied extensively for its anticancer properties. In Chinese hamster ovary cells, PBDE 202 induces apoptosis by inhibiting the activity of specific kinases involved in tumor cell survival. This compound also exhibits potential as a biomarker for measuring kinase activity in urine samples, making it a valuable tool for cancer research and diagnosis. Overall, PBDE 202 holds great promise as an effective anticancer agent with broad applications in medicine and research.</p>

<p>Simvastatin hydroxy acid methyl ester is a drug product that belongs to the group of statins. It is an impurity standard for synthetic simvastatin as well as a natural metabolite formed from simvastatin through oxidation and hydroxylation. This impurity is used in analytical and pharmacopoeia testing for simvastatin, and has been shown to inhibit the production of cholesterol by blocking the synthesis of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR).</p>

<p>(Alphas)-N,N,alpha-trimethyl-3-(4-nitrophenoxy)benzenemethanamine is a drug product that has been synthesized for research and development purposes. It is an impurity in the API (active pharmaceutical ingredient) of this drug product. This compound has been found in the metabolism studies of N-methyl-2-[(2S)-2-[(5S,6S)-5-amino-6-(1H-indol-3-ylmethoxy)-9H-purin-8-yl]-1,1,3,3,-tetramethylbutyl]glycine hydrochloride. The CAS number for this compound is 1346242-32-7.</p>

<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (DMPP) is an analog of the antiarrhythmic drugs flecainide and propafenone. It has the same effects as these drugs, but with a longer duration of action. DMPP is a racemic mixture of two enantiomers, one of which is active against arrhythmias and the other inactive. The drug binds to the beta subunit of voltage gated potassium channels in cardiac muscle cells, preventing the flow of current through these channels. This results in prolongation of the action potential and suppression of arrhythmias. DMPP also inhibits cellulase activity and may be used as an agent for treatment of bacterial infections caused by methicillin resistant Staphylococcus aureus (MRSA).</p>

<p>Please enquire for more information about 2-Cyclopropyl-1-nitro-naphthalene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>9α-Fluoro-6α-methylprednisolone 21-acetate is an analog of the hormone cortisol and has potent anti-inflammatory and immunosuppressive properties. It is also being studied for its potential anticancer activity. This compound inhibits cyclin-dependent kinases, which are involved in regulating cell division and growth. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in animal models. Additionally, it has been found in human urine, indicating that it may have potential as a biomarker for cancer diagnosis or monitoring.</p>

<p>Please enquire for more information about FASN-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about DM3-SMe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-2-Amino-5-phosphonovaleric acid is an inhibitory neurotransmitter that binds to the GABAA receptor. It is used in the treatment of bladder disorders, such as urinary frequency, urgency, and incontinence. L-2-Amino-5-phosphonovaleric acid has been shown to have a depressant effect on the central nervous system and can cause symptoms such as nausea, vomiting, and headache. This drug also has antimicrobial properties due to its ability to inhibit bacterial enzyme activities. L-2-Amino-5-phosphonovaleric acid blocks glutamate receptors in mouse hippocampal cells by binding the alpha1 subunit of the GABAA receptor. This prevents the influx of calcium ions into cells and inhibits phosphorylation of protein kinase C. L(+)-2-Amino-5-phosphonovaleric acid also inhibits pentosan polysulfate sodium,</p>

<p>10-Allyl-2-chloro-phenothiazine is a metabolite of the drug product, Clopidogrel. It is a white crystalline powder that is soluble in water and alcohol. 10-Allyl-2-chloro-phenothiazine is used as an analytical standard for HPLC and NMR studies of Clopidogrel. It also is used as an impurity standard for the determination of purity of this drug product. This chemical belongs to the group of synthetic compounds that are metabolized by humans. Studies have been conducted on its metabolism, which has led to the discovery of its metabolites and their properties. This compound has not been evaluated by any pharmacopoeia or regulatory agency and should be handled accordingly.</p>

<p>Desoxo-palbociclib is a drug product that has been custom synthesized. The purity of this compound is high, with analytical results that meet the pharmacopoeia standards for purity. Metabolism studies have been conducted to determine the natural and synthetic metabolites of this compound. Desoxo-palbociclib is also in Phase II clinical trials for drug development, which are expected to be completed by 2020. There are no known impurities, but there may be traces of other compounds due to its synthetic nature.</p>

<p>OPC-167832 is a potent medicinal compound that has shown promising results in the treatment of cancer. It is an inhibitor of protein kinases, which are enzymes involved in cell cycle regulation and tumor growth. OPC-167832 induces apoptosis, or programmed cell death, in various cancer cell lines including Chinese hamster ovary cells and human tumor cells. This compound has been shown to have anticancer properties by inhibiting the growth of tumors and reducing their size. Additionally, OPC-167832 can be detected in urine samples, making it a useful tool for monitoring treatment response in cancer patients. Overall, this inhibitor shows great potential as a therapeutic agent for the treatment of various types of cancer.</p>

<p>4-Glutathionyl cyclophosphamide is an analog of the anticancer drug cyclophosphamide that has been modified to include a glutathione moiety. This modification enhances the drug's ability to inhibit cancer cell growth by acting as a kinase inhibitor, which prevents cancer cells from dividing and proliferating. In addition, 4-Glutathionyl cyclophosphamide has been shown to induce apoptosis in human tumor cells, leading to their death. This drug also inhibits the activity of dabigatran, a protein involved in blood clotting. 4-Glutathionyl cyclophosphamide is excreted in urine and can be used as a potential biomarker for monitoring cancer treatment efficacy. This drug may also have synergistic effects when used in combination with other chemotherapeutic agents such as chloroquine.</p>

<p>Please enquire for more information about (+)-Papaveroxinoline acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>11β-Hydroxy-5α-pregnane-3,20-dione is a medicinal compound that has been found to have potential anticancer properties. It is a steroid analog that inhibits protein kinases, which are enzymes involved in the regulation of cell cycle and tumor growth. This compound has shown promising results as an inhibitor of various cancer cells in Chinese hamster ovary cells and human urine-derived bladder cancer cells. 11β-Hydroxy-5α-pregnane-3,20-dione may also have applications as an inhibitor of other kinases involved in cancer growth and progression. Its unique chemical structure makes it a promising candidate for further research into its potential therapeutic applications.</p>

<p>Labetalol EP impurity D is a metabolite of labetalol that is used as an impurity standard for HPLC. This impurity has been identified in the drug product and also in the drug development process. Labetalol EP impurity D is one of many metabolites that can be formed by cytochrome P450 enzymes. Labetalol EP impurity D is a natural metabolite of labetalol, which can be found in the urine of humans and other mammals. It is also present in various plants and fungi, including mushrooms, lichens, yeast, and barley. Synthetic labetalol EP impurity D can also be produced by various chemical reactions.</p>

<p>5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine is a chemical compound that is used in various industries. It is commonly used as an intermediate or starting material for the synthesis of other compounds. This compound may contain impurities such as sulfadiazine, glutamate, fatty acids, basic proteins, methanol, acetyltransferase, chemokines, chamomile extract, cellulose, biomass, industrial products, epidermal growth factors, xylose, and growth factors. Please note that this compound is not intended for human consumption and should be handled with care.</p>