APIs for research and impurities

<p>α-Amylcinnamaldehyde dimethyl acetal is a medicinal compound that has shown promise in inhibiting the growth of cancer cells. This compound is an analog of α-amylcinnamaldehyde, a natural product found in Chinese cinnamon bark. Recent studies have shown that α-Amylcinnamaldehyde dimethyl acetal can inhibit the activity of protein kinases, which play a critical role in cell cycle regulation and tumor growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Researchers have also found that this compound has potential as an anticancer agent and may be useful in the development of new cancer treatments. Additionally, it has been detected in urine samples and may serve as a biomarker for certain types of cancer.</p>

<p>Please enquire for more information about 4-o-Benzyl-3-acetyloxy tyrosol α-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-L-Glutamic Acid]-desmopressin is an analytical standard that is used to calibrate HPLC systems. This product is a high purity, synthetic, and drug development API impurity that can be used as a drug product or impurity standard. It is also available as an HPLC standard, niche, and custom synthesis. 4-L-Glutamic Acid]-desmopressin has been shown to have pharmacopoeia and CAS No.</p>

<p>N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-1-naphthalenemethanamine (DHEA) is a human metabolite and an endogenous hormone. DHEA has been shown to have antifungal activity against Candida albicans in vitro. It also possesses an inhibitory effect on the growth of some fungi that are resistant to azole drugs, such as Coccidioides immitis, Cryptococcus neoformans and Blastomyces dermatitidis. DHEA has been used in the treatment of pediatric patients with chronic granulomatous disease and is currently being evaluated for use in other pediatric conditions.</p>

<p>15-Epi travoprost is a synthetic, natural, and impurity standard drug product. It is used in research and development to study metabolism and pharmacology of drugs. 15-Epi travoprost is a metabolite of the drug product Prostaglandin F2α (PGF2α). The chemical name for this compound is 15-(3'-oxo-ethenyl)-prostaglandin F2α. This compound has been shown to be produced by the human body during metabolism of PGF2α. The CAS number for this compound is 1420791-14-5.</p>

<p>Enantiomer of Perindopril t-Butylamine</p>

<p>Gentamicin B1 is a gentamicin antibiotic that is used to treat skin cancer. It inhibits bacterial growth by binding to the 50S ribosomal subunit and blocking protein synthesis. Gentamicin B1 has shown clinical response in patients with wild-type strains of Streptococcus faecalis, but not in those with a mutant strain. The mechanism of action for this drug may involve its ability to inhibit epidermal growth factor (EGF) production. Gentamicin B1 also has been shown to inhibit the proliferation of human cancer cells and induce apoptosis in some tumor cells.</p>

<p>Daidzein 4’-β-D-glucuronide is a bioactive metabolite of daidzein, a type of isoflavonoid. Daidzein 4’-β-D-glucuronide has been shown to have estrogenic activity and is thought to be the major contributor to the biological effects of soy. Daidzein 4’-β-D-glucuronide has been found in the blood samples of healthy individuals, as well as people with estrogen deficiency or taking estrogen supplements. This compound is converted into other forms by the action of enzymes such as glucuronidases and sulfatases. It also undergoes oxidation by cytochrome P450 enzymes and conjugation with glucuronic acid. The pharmacokinetics of this compound are not well understood, but it is thought that its bioavailability may be low due to its hydrophilic properties.</p>

<p>Please enquire for more information about 3-(Aminocarbonyl)-1,6-dimethyl-pyridinium iodide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Iferanserin is a medicinal analog that has shown promising anticancer activity. It is an inhibitor of kinase, a protein that plays a crucial role in cancer cell growth and tumor formation. Iferanserin induces apoptosis, or programmed cell death, in cancer cells by disrupting the cell cycle. This drug has been studied extensively in Chinese patients with various types of cancer and has shown significant antitumor effects. Iferanserin acts as a potent inhibitor of protein kinases, which are enzymes that regulate cellular processes such as gene expression, cell division, and differentiation. It is excreted primarily in urine and may have potential as a novel therapy for cancer treatment.</p>

<p>BGC 20-1531 is a synthetic drug product that is an impurity standard for the API, with a purity of 99.7%. BGC 20-1531 is also used as an analytical reference material and has been shown to be metabolized in both rats and humans. It can be used to study metabolism in animals and humans. The chemical name for this compound is 3-(2,4-dichlorophenyl)-5-[(1R,2S)-2-hydroxypropyl]-thiophene-2-carbonitrile hydrochloride.</p>

<p>Tazarotene is a synthetic retinoid that is used in the treatment of psoriasis and acne vulgaris. Tazarotene sulfoxide is the active metabolite of tazarotene. It has been shown to have an acidic pH, and it can be photolysed by exposure to light. Tazarotene sulfoxide has been shown to be reproducible and reliable for analytical purposes and can be used as an additive for medicines.</p>

<p>5-Hydroxyindole-3-acetic acid-d2 is a drug product that can be used as an analytical reference standard for HPLC. It is also used as a metabolite in the metabolism studies of 5-hydroxyindole-3-acetic acid, a natural and synthetic compound. This product is manufactured synthetically and has been shown to have a purity of &gt;98%. It is also manufactured for use in pharmacopoeias and can be used as an API impurity standard.</p>

<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>

<p>Amoxicillin trihydrate impurity C is an impurity that is formed during the production of amoxicillin. It has been detected in amoxicillin samples with a flow rate of less than 1 mL/min, which is higher than the detection limit of 0.1% for this impurity. Amoxicillin trihydrate impurity C has been shown to have anti-fungal activity against Candida albicans and Saccharomyces cerevisiae. This impurity can be removed by dehydration or chromatographic methods, such as liquid chromatography.</p>

<p>2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide is a drug product that is Custom synthesized. It has a high purity and analytical quality. Metabolism studies have been conducted on this compound. Natural and synthetic sources are available for this compound. It is found in the Drug Development section of the pharmacopoeia. The CAS number for this compound is 1194434-39-3, and it has an Impurity Standard as well as an HPLC standard.</p>

<p>Dihydrocephalomannine is a natural product that is used as a reagent in the synthesis of other molecules. It can be found in plants such as Taxus brevifolia, which contains the molecule taxol. Dihydrocephalomannine is synthesized by benzoylation and hydroxylation of dihydrobenzofuran. The molecule has been shown to have cytotoxic activity against human ovarian cancer cells, but its mechanism of action is not yet known.</p>

<p>7-(4-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}butoxy)-3,4-dihydroquinolin-2(1H)-one is an analytical reference standard for HPLC. It is a white to light yellow crystalline powder that is soluble in water and ethanol. This compound has been synthesized from 4-(2,3-dichlorophenyl)piperazine and 3,4-dihydroquinoline 2(1H)-one. This molecule has been identified as an impurity in the drug product, Cefdinir (7-(2-(3,4-Dihydroxyphenoxy)propoxy)-3,4-dihydroquinolin-2(1H)-one). The purity of this chemical has been shown to be greater than 99.5% by high performance liquid chromatography (HPLC).</p>

<p>Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.</p>

<p>Ruxolitinib Impurity 3 is an analytical chemical that is used as a reference standard in the field of drug development. It is a high purity, HPLC-grade chemical that meets the requirements set by the U.S. Pharmacopoeia (USP) and is manufactured using natural or synthetic methods. This compound has been shown to be an impurity in Ruxolitinib, which is an API for treating myelofibrosis and thrombocythemia. Ruxolitinib Impurity 3 has also been found to be a metabolite of ruxolitinib, with a molecular weight of 2102675 daltons and CAS number 2102675-40-9.</p>