Amino Acids (AA)

<p>Applications 2-Methylnaphth[1,2-d]oxazole (cas# 85-15-4) is a useful research chemical.<br></p>

<p>Applications 4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions.<br>References Zhang, K. et al.: Chin. J. Chem., 28, 509 (2010); Zhao, S. et al.: Tetra. Lett., 52, 2702 (2011);<br></p>

<p>Stability Hygroscopic<br>Applications 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester is a possible metabolite of the di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) monoester (MINCH).<br>References Koch, H., et al.: Arch. Toxicol., 87, 799 (2013)<br></p>

<p>Applications N-Methyl-N-nitroso-1-hexadecanamine is a compound found in a wide range of cosmetic products and cleaning emulsions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kamp, E.. et al.: Food. Chem. Toxicol., 29, 203 (1991); Lalljie, S. P. D., et al.: Adv. Mass. Spec., 14, 33790 (1998); Abidi, S.L., et al.: J. Chroma., 324, 209 (1985);<br></p>

<p>Applications The main metabolite of o-xylene.<br>References Gregus, Z., et al.: Drug Metab. Dispos., 26, 1082 (1998), Gregus, Z., et al.: Xenobiotica, 29, 547 (1999), Gonzalez-Reche, L., et al.: Arch. Toxicol., 77, 80 (2003),<br></p>

<p>Applications N-Methyldiethanolamine-13C,d3 Hydrochloride is isotopically labelled salt form of N-Methyldiethanolamine (M301625), which is used as a reagent in the synthesis of broad-spectrum antimicrobial polycarbonate hydrogels with fast degradability. It is also used as a reagent in the synthesis of dihydroxy quaternary ammonium salts with long chain alkyl bromides that can exhibit antibacterial and antifungal activity.<br>References Pascual, A., et al.: Biomacromolecules, 16, 1169 (2015); Liu, W., et al.: Chem. Biol. Drug Des., 85, 91 (2015);<br></p>

<p>Applications Ethametsulfuron-methyl is a regulator of the early steps of complement activation on mucosal surfaces. It can be used in combination treatment of ohmic heating with various essential oil components for inactivation of food-​borne pathogens in buffered peptone water and salsa.<br>References Kim, S. S., et al.: Food Control, 80, 29 (2017); Reichhardt, M. P., et al.: Front Immunol, 7, 85 (2016)<br></p>

<p>Applications (1-Methyl-1H-imidazol-2-yl)-acetic acid (cas# 118054-54-9) is a useful research chemical.<br></p>

<p>Applications N-(2-Hydroxyethyl)glycine (~90%) (cas# 5835-28-9) is a compound useful in organic synthesis.<br></p>

<p>Applications (2S,4R)-4-Hydroxy-L-glutamic Acid is a metabolite of Glutamic acid (G596960).<br>References Hampson, D., et al.: J. Biol. Chem., 274, 33488 (1999), Jensen, A., et al.: Eur. J. Pharmacol., 397, 247 (2000),<br></p>

<p>Applications (E)-Ethyl 4-Bromo-3-methyl-2-butenoate (cas# 51318-62-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N1-(2-AMINOETHYL)-N1-METHYLETHANE-1,2-DIAMINE (cas# 4097-88-5) is a useful research chemical.<br></p>

<p>Applications A nitroamino subsituted primary alcohol.<br></p>

<p>Impurity Duloxetine EP Impurity B<br>Applications A Duloxetine intermediate. Duloxetine EP Impurity B.<br></p>

<p>Applications Labeled Sucrose (S697000). Yuanzhen sugar is a polysaccharide polymer, containing a certain amount of fructooligosaccharides.<br>References Watanabe, T., et al.: Biosci. Biotech. Biochem., 72, 3167 (2008), You, Y., et al.: J. Agric. Food Chem., 57, 709 (2009),<br></p>

<p>Applications 5-Carboxy-2-methylphenylboronic Acid acts as a reagent in the synthesis of pyrazolopyridinone-based p38 MAP kinase inhibitor<br>References Milburn, R. R., et al.: Org. Process Res. Dev., 15, 31 (2011); Achmatowicz, M., et al.: J. Org. Chem., 74, 795 (2009)<br></p>

<p>Stability Hygroscopic<br>Applications 2-Fluoro-4-methylphenylboronic Acid (cas# 170981-26-7) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications 5-Methyl-2-furanmethanol (cas# 3857-25-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(3,4-Dimethylphenyl)-3-methyl-1H-pyrazol-5(4H)-one is a reagent used in the enantioselective aminoalkylation of pyrazol-3-ones.<br>References Carceller-Ferrer, L. et al.: Org. Biomol. Chem., 17, 9859 (2019);<br></p>

<p>Stability Extremely Hygroscopic<br>Applications Labelled L-Arginine (A769500). An essential amino acid for human development. Precursor for nitric oxide. Ammonia detoxicant (hepatic failure); diagnostic aid (pituitary function).<br>References Miura, T., et al.: Anal. Biochem., 139, 432 (1984), Jones, et al.: Adv. Enzyme Regul., 9, 19 (1970), Borders, C.L., et al.: Protein. Sci., 3, 541 (1994),<br></p>

<p>Applications Perfluoro-4-Methoxybutanoic Acid (cas# 863090-89-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications It can be degraded efficiently by the QL-degrading bacteria.<br>References Shukla, O., et al.: Microbios., 59, 47 (1989), Oh, Y; Biotechnol Bioeng 1994, 44, 533,,,<br></p>

<p>Applications Sorbicillin analog. A bioactive secondary metabolites from terrestrial Streptomyces species TN262.<br>References Ma, L. et al. : J. Anitibiot. 64, 645 (2011); Elleuch, L. et al.: Appl. Biochem. Biotech. 162, 579 (2010)<br></p>

<p>Applications L-Leucine is an essential amino acid. L-Leucine acts as a nutrient signal to stimulate protein synthesis. It has also activates the mammalian target of rapamycin kinase that regulates cell growth.<br>References Demant, T. et al.: Am. J. Physiol., 270, E1022 (1996); Diraison, F. et al.: Am. J. Physiol., 277, E529 (1999); Suryawan, A. et al.: J. Anim. Sci., 89, 2004 (2011); Peyrollier, K. et al.: Biochem. J., 350, 361 (2000);<br></p>

<p>Stability Moisture Sensitive<br>Applications An inhibitor of alkaline phosphatase isoenzymes. An analog of Homoarginine (H585000).<br>References Muth, W., et al.: J. Biol. Chem., 249, 7463 (1974), Hanukoglu, I., et al.: Eur. J. Biochem., 180, 479 (1989), Khaw, L., et al.: J. Bacteriol. 180, 809 (1998), Gallagher, D., et al.: J. Mol. Biol., 342, 119 (2004),<br></p>

<p>Applications N-Acetyl-S-benzyl-d5-L-cysteine is deuterium labelled N-Acetyl-S-benzyl-L-cysteine, which is a metabolite of toluene.<br>References Gargas, M., et al.: Toxicol. Appl. Pharmacol., 98, 87 (1989), Commandeur, J., et al.: Pharmacol. Rev., 47(2), 271 (1995), Campo, P., et al.: Neurotoxicol. Teratol., 21, 427 (1999), Lohse, C., et al.: J. Agr. Food Chem., 48, 5913 (2000),<br></p>

<p>Stability Hygroscopic<br>Applications Labelled 3-Aminoisobutyric Acid (A611585). Substituted β-alanines. Used for preparation and isolation of D(-)-β-aminoisobutyric acid.<br>References Kakimoto, Y., et al.: J. Biol. Chem., 236, 3288 (1961),<br></p>

<p>Applications A metabolite of Crotonaldehyde.<br>References Gray, J.M., et al.: Xenobiotica, 1, 55 (1971), Chung, F., et al.: Mutat. Res., 424, 71 (1999), Smith, C., et al.: Food Chem. Toxicol., 38, 637 (2000), Pan, J., et al.: Chem. Res. Toxicol., 15, 367 (2002),<br></p>

<p>Stability Hygroscopic<br>Applications Oleoyl-L-carnitine is a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Oleoyl-L-carnitine can be diagnostic for a number of ß-oxidation defects.<br>References Adams, S., et al.: J. Nutrition, 139, 1073 (2009); Ventura, F., et al.: Clinica Chimica Acta, 281, 1 (1999); Pourfarzam, M., et al.: Clinical Chem,, 40, 2267 (1994); Schaefer, J., et al.: Pediatric Res., 37, 354 (1995)<br></p>

<p>Applications 2-Deoxy-2-chloro-D-glucose is a D-Glucose (G595000) derivative used in the synthesis of sugar nucleotides and oligosaccharides.<br>References Herr, D., et al.: Euro. J. App. Microbiol., 1, 41 (1975);<br></p>

<p>Applications L-Aspartyl-L-phenylalanine is an impurity of Thiamine (T344185). Thiamine Impurity B.<br>References Aluwihare, L., et al.: Science, 308, 1007 (2005), Koch, B., et al.: Anal. Chem., 79, 1758 (2007), Reemtsma, T., et al.: Environ. Sci. Technol., 42, 1430 (2008),<br></p>

<p>Applications N-Methyl-L-alanine is a reactant used in the preparation of site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity.<br>References Pillow, T.H., et. al.: J. Med. Chem., 57, 7890 (2014)<br></p>

<p>Impurity Flumazenil EP Impurity E<br>Applications Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate (Flumazenil EP Impurity E) is used in the biological studies and preparation of imidazobenzodiazepines as probes for diazepaminsensitive receptor pharmacophore.<br>References Zhang, P., et al.: J. Med. Chem., 38, 1679 (1995)<br></p>

<p>Stability Hygroscopic<br>Applications A metabolite of Catecholamines.<br>References Kopin, I.J., et al.: J. Biol. Chem., 236, 2109 (1961), Short, F.W., et al.: J. Med. Pharm. Chem., 5, 642 (1962)<br></p>

<p>Applications L-Carnitine-d9 is the isotope labelled analog of L-Carnitine (C184110); an essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthesized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.<br>References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978); Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001); Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002); Karlic, H., et al.: Nutrition, 20, 709 (2004)<br></p>

<p>M06199 - BOC-SER(TBU)-OH DCHA</p>

<p>Applications cis-Propenylphosphonic Acid (R)-(+)-α-Methylbenzylamine Salt is used as a reagent in the microbial production of Fosfomycin (F727505); a compound used as an antibiotic in the treatment of urinary tract infections.<br>References Watanabe, M., et al.: Appl. Environ. Microb., 65, 1036 (1999); Itoh, N., et al.: Appl. Microbiol. Biot., 43, 394 (1995); White, R.F., et al.: Appl. Microbiol., 22, 55 (1971); Keating, G. et al.: Drugs, 73, 1951 (2013); Demir, T. et al.: Int. J. Infect. Dis., 17, e966 (2013)<br></p>

<p>Stability Hygroscopic<br>Applications A labelled metabolite of Methyl isocyanate.<br>References Slatter, J. G., et al.: Chem. Res. Toxicol., 4, 157 (1991),<br></p>

<p>Applications 1-(2-Isopropylthiazol-4-yl)-N-methylmethanamine dihydrochloride (cas# 1185167-55-8) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives as antithrombotics. It is also used as a reagent in the synthesis of diamide derivatives as FXa inhibitors. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is an intermediate for Edoxaban (E555520).<br>References Mochizuki, A., et al.: Jpn. Kokai Tokkyo Koho. JP 2010120852 A 20100603. Jun 3, 2010; Mochizuki, A., et al.: PCT Int. Appl. WO 2008123017 A1 20081016. Oct 16, 2008<br></p>

<p>Applications 6-Methylmercaptopurine Riboside (cas# 342-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-methyl-1-[4-(trifluoromethyl)phenyl]propan-1-one (cas# 64436-58-4) is a useful research chemical.<br></p>

<p>Applications: 3-Methyl-2,5-dihydrothiophene-1,1-dioxide is a reagent used in Diels-Alder reactions of butadienylpyridinium bromides.<br>References Lee, S., et al.: J. Org. Chem., 62, 7812 (1997);<br></p>

<p>Applications A labelled derivative of Dibarbituric acid.<br>References Hitchings, G.H., et al.: J. Biol. Chem., 177, 357 (1949),<br></p>

<p>Applications A product from thermal and hydrolytic degradation of Orlistat. Orlistat impurity.<br>References Stalder, H., et al.: Helv. Chimica Acta, 75, 1593 (1992),<br></p>

<p>Applications Ademethionine-d3 1,4-Butanedisulfonate, is a labeled analogue of Ademethionine 1,4-Butanedisulfonate (A280355), used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.<br></p>

<p>Applications A Boc-protected bifunctional linking reagent.<br>References Jimenez-Castells, C., et al.: Bioorg. Med. Chem. Lett., 17, 5155 (2007), Carmona, S., et al.: Mol. Pharm., 6, 706 (2009), Nagahori, N., et al.: Biochem., 48, 583 (2009),<br></p>

<p>Applications 4-Methoxy-3-nitrobenzonitrile<br></p>

<p>Stability Hygroscopic<br>Applications Trigonelline-d3 HCl is deuterium labelled Trigonelline HCl. Trigonelline HCl has utility in developing site-specific system that delivers drugs to the brain. It has also been suggested as a potential anti-Alzheimer disease agent.<br>References Bodor, N., et al.: J. Med. Chem 26, 313 (1983); Makowska, J., et al.: J. Chromatogr. B 968, 101 (2014)<br></p>

<p>Applications N-Methylformamide is used in amidation or transamidation chemical reactions where formamide is insufficient.<br>References Rao, S. et al.: Org. Lett., 15, 1496 (2013); Xu, K. et al.: Chem. A. Eur. J., 18, 9793 (2012);<br></p>

<p>Applications 5-Methoxy-N-methyl-N-(1-methylethyl)-α-oxo-1H-indole-3-acetamide is an intermediate used in the synthesis of 5-Methoxy-N-methyl-N-isopropyl Tryptamine (M271680), which is a psychedelic tryptamine related to N-methyl-N-isopropyltryptamine. 5-Methoxy MiPT potently inhibits the re-uptake of the monoamines serotonin and norepinephrine but does not affect dopamine re-uptake. 5-Methoxy MiPT has no effect on the release of monoamines from rat brain synaptosomes. This product is intended for forensic and research applications.<br>References Katagi, M., et al.: Jpn. J. Forensic Toxicol., 20, 303 (2002), Meatherall, R., et al.: J. Anal. Toxicol., 27, 313 (2003), Wilson, J., et al.: Forensic Sci. Int., 148, 31 (2005), Kamata, T., et al.: Drug Metab. Dispos., 34, 281 (2006),<br></p>

<p>Applications 1-Ethyl-1-methylcyclopentane, is one of the chemical components of Gas-Phase organic carbon emissions from motor vehicles. It is also a volatile component of frying oils.<br>References Gentner, D. R., et al.: Environ. Sci. Tech., 47, 11937 (2013); Prevot, A. Frying Food, 155 (1988);<br></p>

<p>Applications 2-bromo-N-methoxy-N-methylbenzamide (cas# 899425-05-9) is a useful research chemical.<br></p>

<p>Applications (3-Glycidoxypropyl)triethoxysilane is used in the fabric industry to treat and modify fabrics.<br>References Schramm, Christian, et al.: Coloration Tech., 133(3), 234-242 (2017);Grancaric, Ana Marija, et al.: Pro. in Org. Coatings, 103, 174-181 (2017); Yeo, Jun-Seok, et al.: J. of Ind. and Eng. Chem., 45, 301-306 (2017)<br></p>

<p>Applications 1,3,5-Trimethoxy-2-methylbenzene AldrichCPR (cas# 14107-97-2) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxy-2-methylbutanoic Acid (cas# 473-86-9) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Methyltaurine Sodium Salt is used in the analysis of the changing properties of anionic surfactants and the development of new skin cleansers or soaps. It is the salt of N-Methyltaurine, a compound used in sperm cryopreservation studies. N-Methyltaurine is also used in the studies relating to effects on oxidative damage to erythrocytes via phenylhydrazine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pokhrel, P.K. et al.: Adv. Exp. Med. Biol., 483, 503 (2000); Miyahara, R. et al.: Fragr. J., 28, 11 (2000); Garde, J.J. et al.: Bio. Repro., 69, 602 (2003);<br></p>

<p>Stability Hygroscopic<br>Applications Ferrous Bisglycinate is used in the fortification of infant formulations and foods.<br>References Fox, T. et al.: Am. J. Clin. Nutri., 67, 664 (1998); Heath, A. et al.: J. Am. Coll. Nutr., 20, 477 (2001);<br></p>