Amino Acids (AA)

<p>Applications 2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.<br>References Antonysamy, S., et al.: Bioorg. Med. Chem. Lett., 18, 2990 (2008); Kazmierski, W., et al.: PCT Int. Appl. (2004), WO 2004054974 A2 20040701<br></p>

<p>Applications N-Methyl-3,3-diphenylpropylamine is an intermediate for the synthesis of SNRI-NMDA antagonist and neuroprotectants.<br>References Olney, J. et al.: Sci., 244, 1360 (1989); Williams, W., et al.: Mol. Pharmacol. 44, 851 (1993);<br></p>

<p>Applications 2-Oxo-3-methylbutanoic acid (cas# 759-05-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3'-Methylacetophenone is a reagent that is used in the preparation of 3-aryl-6-phenylimidazo[2,1-b]thiazoles which has anticancer properties.<br>References Koppireddi, S., et al.: Bioorg. Med. Chem. Lett., 24, 5428 (2014);<br></p>

<p>Stability Volatile<br>Applications 2-Chloro-2-Methylpentane (cas# 4325-48-8) is a useful research chemical.<br></p>

<p>Applications Used in the methods of detecting nitrotyrosine and aminotyrosine residues of peptides and proteins. Also used in the studies on the separation and photometric determination of antiepileptics.<br>References Quednow, B., et al.: Pharmazie, 34, 724 (1979),<br></p>

<p>Applications N-Methylaniline is used as an additive in gasoline because of its antiknock properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, Li-jun, et al.: Huaxue Shiji, 37(1), 53-55, 96 (2015); Qin, Li-xia, et al.: Guangzhou Huagong, 43(8), 138-139, 148 (2015);<br></p>

<p>Applications N'-tert-Butyl-3-methoxy-2-methylbenzohydrazide is an intermediate used in the synthesis of methoxyfenozide; an active ingredient for the commercial production of certain insecticidal and pesticidal formulations.<br>References Shao, J., et al.: Xiandai Nongyao, 2, 12, (2003), Mao, W. T., et al.: Chin. Chem. Lett., 23, 1233 (2012)<br></p>

<p>Applications 5-((2-Hydroxyethyl)amino)-2-methylphenol (cas# 55302-96-0) is a useful research chemical.<br></p>

<p>Applications Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid is a reactant used in the preparation of peptidase IV inhibitors.<br>References Park, W. et al.: Bioorg. Med. Chem. Lett., 21, 1366 (2011);<br></p>

<p>Impurity Ciclopirox EP Impurity B/ USP Ciclopirox Related Compound B<br>Applications 6-Cyclohexyl-4-methyl-2H-pyran-2-one (Ciclopirox EP Impurity B) is a a dialkylated pyranone derivative.<br></p>

<p>Applications 4-Methyl-2(5H)-furanone (cas# 6124-79-4) is a useful research chemical.<br></p>

<p>Applications 3-Methylbutyric-2,2-d2 Acid (CAS# 95927-02-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Methyl-d3-indole has been used to prove that bioactivation of the pulmonary toxin 3-methylindole requires methyl carbon-hydrogen bond breakage in mice. 3-Methyl-d3-indole is the labeled analogue of 3-Methylindole (M313470), A naturally abundant pneumotoxin, found primarily in mammalian feces providing its strong fecal odor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huijzer, J., et. al.: Toxicol. Appl. Pharm., 90, 60 (1987); Nakashima, T., et al.: Biol. Pharm. Bull., 32, 832 (2009); Xu, H., et al.: Chem. Pharm. Bull., 57, 321 (2009); Bodoor, K., et al.: J. Med. Chem., 52, 3753 (2009); Naskar, S., et al.: J. Chem. Res., 3, 174 (2009); Sollner, K., et al.: J. Agric. Food Chem., 57, 4319 (2009)<br></p>

<p>Applications Used in the synthesis of Capsaicin analogues, useful for their anti-tumor activity.<br>References Fusco, B., et al.: Drugs, 53, 909 (1997), Buisman, G., et al.: Biotechnol. Lett., 20, 131 (1998), Kobata, K., et al.: Bios. Biotechnol. Biochem., 66, 319 (2002), Aluru, M., et al.: J. Exp. Bot., 54, 1655 (2003),; Wang, W. et al.: Gaodeng Xuexiao Huaxue Xuebao 31, 2400(2010)<br></p>

<p>Applications Used in the synthesis of DMPO-type spin traps.<br>References Konaka, R., et al.: Free Radical Res., 23, 15 (1995),<br></p>

<p>Applications 8-Chloro-4-hydroxy-2-methylquinoline (cas# 5236-87-3) is a useful research chemical.<br></p>

<p>Impurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F<br>Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);<br></p>

<p>Applications N-Acetyl-S-phenyl-d5-DL-cysteine is the deuterium labelled form of N-Acetyl-S-phenyl-DL-cysteine, which is used as a reactant in the preparation of potent HIV-1 protease inhibitors that use D-amino acids as P2/P3 ligands.<br>References Jungheim, L., et al.: J. Med. Chem., 39, 96 (1996);<br></p>

<p>Applications N-Methylformamide is used in amidation or transamidation chemical reactions where formamide is insufficient.<br>References Rao, S. et al.: Org. Lett., 15, 1496 (2013); Xu, K. et al.: Chem. A. Eur. J., 18, 9793 (2012);<br></p>

<p>Applications L-Lysine-3,3,4,4,5,5,6,6-d8 Dihydrochloride, is the labelled L-Lysine, a naturally occurring amino acid which is used in the labelling of human bone marrow mesenchymal stem cells for analysis.<br>References Rocha, B. et al.: J. Prot. Res., 11, 5350 (2012); Kumar, D. et al.: Polym. J., 45, 160 (2013);<br></p>

<p>Applications 3-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic Acid is used in the synthesis of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase. Also used in the synthesis of 4-carboxamide derivatives acting as antifungal agents.<br>References Cheng, G. et al.: Bioorg. Med. Chem. Lett., 23, 2035 (2013); Wu, Z. et al.: Molecules, 17, 14205 (2012);<br></p>

<p>Stability Air Sensitive<br>Applications N-Methyl-L-cysteine Hydrochloride is an intermediate used to prepare analogs of pyochelin (P840365), a siderophore of Pseudomonas aeruginosa.<br>References Rivault, F., et al.: Tetrahedron, 60, 12139 (2004); Noel, S., et al.: Bioorgan. Chem. Lett., 24, 132 (2014); Ankenbauer, R., et al.: J. Bacteriol., 170, 5344 (1988)<br></p>

<p>Applications 3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine, can beused in the synthesis of Dibenzo[c,f][1,2]thiazepine derivatives.<br>References Gilleron, P., et al.: Bioorg. Med. Chem. Lett., 17, 5465 (2007),<br></p>

<p>Applications 3-Methyl-3-hepten-5-one is a reagent used to prepare fused nitrogen-heterocycles from β-enamino nitrile and α,β-unsaturated carbonyl compounds.<br>References Nemes, P., et al.: Synlett., 2, 222 (1999)<br></p>