CAS 10416-59-8

N,O-Bis(trimethylsilyl)acetamid

Beschreibung:

N,O-Bis(trimethylsilyl)acetamid, allgemein bekannt als BSA, ist eine chemische Verbindung, die durch ihre Verwendung als Derivatisierungsreagenz in der analytischen Chemie, insbesondere in der Gaschromatographie und der Massenspektrometrie, gekennzeichnet ist. Sie weist eine Struktur auf, die zwei Trimethylsilylgruppen enthält, die an die Stickstoff- und Sauerstoffatome einer Acetamid-Gruppe gebunden sind, was ihre Fähigkeit verbessert, stabile Derivate mit polaren funktionellen Gruppen zu bilden. Diese Verbindung ist typischerweise eine farblose bis blassgelbe Flüssigkeit mit einem relativ niedrigen Siedepunkt, was sie für verschiedene Anwendungen in der organischen Synthese und der Probenvorbereitung geeignet macht. BSA ist bekannt für seine Fähigkeit, die Flüchtigkeit und thermische Stabilität von Analyten zu verbessern, was deren Detektion und Quantifizierung erleichtert. Darüber hinaus ist es unter Standardlaborbedingungen relativ stabil, sollte jedoch aufgrund seiner Reaktivität mit Feuchtigkeit und der Möglichkeit, Trimethylsilanol bei Hydrolyse freizusetzen, mit Vorsicht behandelt werden. Insgesamt ist N,O-Bis(trimethylsilyl)acetamid ein wertvolles Werkzeug im Bereich der analytischen Chemie zur Verbesserung der Analyse komplexer Mischungen.

Formel: C₈H₂₁NOSi₂

InChl: InChI=1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3

InChI Key: InChIKey=SIOVKLKJSOKLIF-UHFFFAOYSA-N

SMILES: N([Si](C)(C)C)=C(O[Si](C)(C)C)C

Synonyme:

• Acetimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester
• BSA
• Bis trimethyl silyl acetamide
• Bis(trimethylsilyl)acetamide
• Bis(trimethylsilyl)acetimidate
• Dynasylan Bsa
• Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester
• Ls 7270
• N,O-BIS-(Trimethyl silyl)-acetamide
• N,O-Bis(trimethylsilyl)aectamide
• N,O-Bis-trimethylsilylacetoamide
• N,O-Di(trimethylsilyl)acetamide
• N-(Trimethylsilyl)acetimidic acid trimethylsilyl ester
• N-(Trimethylsilyl)ethanimidic acid trimethylsilyl ester
• NO-Bis (trimethylsilyl) acetamide
• O,N-Bis(trimethylsilyl)acetamide
• trimethylsilyl (1E)-N-(trimethylsilyl)ethanimidoate
• trimethylsilyl N-(trimethylsilyl)ethanimidoate
• trimethylsilyl N-trimethylsilylacetamidate

N,O-Bis(trimethylsilyl)acetamide [Trimethylsilylating Agent]

CAS: 10416-59-8

Formel: C₈H₂₁NOSi₂

Reinheit: >80.0%(GC)

Farbe und Form: Colorless to Light yellow clear liquid

Molekulargewicht: 203.43

Ref: 3B-B0511

N,O-Bis(trimethylsilyl)acetamide (25% in Acetonitrile) [Trimethylsilylating Reagent, for NH2 compounds]

CAS: 10416-59-8

Farbe und Form: Colorless to Light yellow clear liquid

Ref: 3B-B0510

N,O-Bis(trimethylsilyl)acetamide Kit BSA 1 mL × 8 / Reaction vial, capacity 2 mL × 8

CAS: 10416-59-8

Reinheit: >80.0%(GC)

Farbe und Form: Colorless to Light yellow clear liquid

Ref: 3B-B0911

BSA [=N,O-Bis(trimethylsilyl)acetamide] [for Gas Chromatography]

CAS: 10416-59-8

Formel: C₈H₂₁NOSi₂

Reinheit: >80.0%(GC)

Farbe und Form: Colorless to Light yellow clear liquid

Molekulargewicht: 203.43

Ref: 3B-A5601

TMS-BA [=N,O-Bis(trimethylsilyl)acetamide] (25% in Acetonitrile) [for Gas Chromatography]

CAS: 10416-59-8

Reinheit: No impurity higher than Isopropyl myristate(50 ppm) after 5 min + hold up time

Farbe und Form: Colorless to Light yellow clear liquid

Ref: 3B-A5602

N,O-Bis(trimethylsilyl)acetamide, 95%

CAS: 10416-59-8

N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloi

Formel: C₈H₂₁NOSi₂

Reinheit: 95%

Farbe und Form: Clear, colorless to pale yellow, Liquid

Molekulargewicht: 203.43

Ref: 02-L00183

N,O-Bis(Trimethylsilyl)Acetamide

CAS: 10416-59-8

Formel: C₈H₂₁NOSi₂

Reinheit: 95%

Farbe und Form: Liquid

Molekulargewicht: 203.4294

Ref: IN-DA00399B

N,O-Bis(trimethylsilyl)acetamide

CAS: 10416-59-8

Formel: C₈H₂₁NOSi₂

Reinheit: (GC) ≥ 94.0%

Farbe und Form: Clear, colourless to light yellow liquid

Molekulargewicht: 203.43

Ref: 7W-GK3085

Trimethylsilyl N-(trimethylsilyl)acetimidate

CAS: 10416-59-8

Trimethylsilyl N-(trimethylsilyl)acetimidate

Formel: C₈H₂₁NOSi₂

Reinheit: 97%

Farbe und Form: clear. almost colourless liquid

Molekulargewicht: 203.42943g/mol

Ref: 54-OR5155A

N,O-Bis(trimethylsilyl)acetamide Kit TMS-BA (25% in Acetonitrile) 1 mL × 8 / Reaction vial, capacity 2 mL × 8 [Trimethylsilylating Reagent, for NH2 compounds]

CAS: 10416-59-8

Farbe und Form: Colorless to Light yellow clear liquid

Ref: 3B-T0691

N,O-Bis(trimethylsilyl)acetamide (BSA)

CAS: 10416-59-8

S02375 - N,O-Bis(trimethylsilyl)acetamide (BSA)

Formel: C₈H₂₁NOSi₂

Reinheit: >97%

Farbe und Form: Clear

Molekulargewicht: 203.432

Ref: 10-S02375

N,O-Bis(trimethylsilyl) Acetamide

CAS: 10416-59-8

Formel: C₈H₂₁NOSi₂

Molekulargewicht: 203.43

Ref: 4Z-A-133025

N,O-Bis(trimethylsilyl)acetamide

Kontrolliertes Produkt

CAS: 10416-59-8

Applications N,O-Bis(trimethylsilyl)acetamide is used as a reagent in the synthesis of 4'-spirocyclic phosphono-nucleosides as potential inhibitors of hepatitis C virus NS5B polymerase. Also used as a reagent in the microwave-assisted synthesis of purine nucleosides as selective cholinesterase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dang, Q., et al.: Tetrahedron Lett., 55, 4407 (2014); Schwarz, S., et al.: Org. Biomol. Chem., 12, 2446 (2014)

Formel: C₈H₂₁NOSi₂

Farbe und Form: Neat

Molekulargewicht: 203.43

Ref: TR-B588675

N,O-Bis(trimethylsilyl) acetamide

CAS: 10416-59-8

N,O-Bis(trimethylsilyl) acetamide is a protein that is used as a reagent for the detection of integrin receptors. It can be used to identify human immunoglobulin and human serum proteins. This compound has been shown to be pluripotent in cells, which means that it can differentiate into any type of cell. N,O-Bis(trimethylsilyl) acetamide has been shown to have surfactant properties and can be used as an alternative in toxicity studies. This compound has been shown to be toxic to bowel disease cells when tested with a dose of 3mg/mL. The disulfide bond within this molecule may be important for its biological activity. Synchronous fluorescence spectroscopy and plasma mass spectrometry are two methods that have been used to study the structure of this molecule. Electrochemical impedance spectroscopy is another method that has been used in the structural analysis of this molecule.

Formel: C₈H₂₁NOSi₂

Reinheit: Min. 95 Area-%

Farbe und Form: Colorless Yellow Clear Liquid

Molekulargewicht: 203.43 g/mol

Ref: 3D-FB03098

N,O-BIS(TRIMETHYLSILYL)ACETAMIDE

CAS: 10416-59-8

Trimethylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Alkyl Silane - Conventional Surface Bonding
Aliphatic, fluorinated aliphatic or substituted aromatic hydrocarbon substituents are the hydrophobic entities which enable silanes to induce surface hydrophobicity. The organic substitution of the silane must be non-polar. The hydrophobic effect of the organic substitution can be related to the free energy of transfer of hydrocarbon molecules from an aqueous phase to a homogeneous hydrocarbon phase. A successful hydrophobic coating must eliminate or mitigate hydrogen bonding and shield polar surfaces from interaction with water by creating a non-polar interphase. Although silane and silicone derived coatings are in general the most hydrophobic, they maintain a high degree of permeability to water vapor. This allows coatings to breathe and reduce deterioration at the coating interface associated with entrapped water. Since ions are not transported through non-polar silane and silicone coatings, they offer protection to composite structures ranging from pigmented coatings to rebar reinforced concrete. A selection guide for hydrophobic silanes can be found on pages 22-31 of the Hydrophobicity, Hydrophilicity and Silane Surface Modification brochure.
Bis(Trimethylsilyl)acetamide; N,O-Bis(trimethylsilyl)acetamide; Trimethylsilyl-N-Trimethylsilylacetamidate; BSA
More reactive than SIH6110.0Releases neutral acetamide upon reactionBoth silyl groups usedUsed for silylation in analytical applicationsReactions catalyzed by acidForms enol silyl ethers in ionic liquidsNafion SAC-13 has been shown to be a recyclable catalyst for the trimethylsilylation of primary, secondary, and tertiary alcohols in excellent yields and short reaction timesSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

Formel: C₈H₂₁NOSi₂

Reinheit: 95%

Farbe und Form: Straw Liquid

Molekulargewicht: 203.43

Ref: 3H-SIB1846.0

N,O-Bis-(Trimethylsilyl) Acetamide (BSA) extrapure, 95%

CAS: 10416-59-8

Formel: C₈H₂₁NOSi₂

Reinheit: min. 95.0%

Farbe und Form: Clear, Colourless to pale yellow, Liquid

Molekulargewicht: 203.43

Ref: SR-26477