![Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F382836-5-o-44-dimethoxytrityl-5-methyl-n4-benzoyl-2-deoxycytidine-3-2-cyanoethyl-n-n-diisopropyl-phosphoramidite.webp&w=3840&q=75)
CAS 105931-57-5
:Cytidin, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-desoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit]
Beschreibung:
Cytidin, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-desoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit] ist eine komplexe chemische Verbindung, die hauptsächlich im Bereich der Nukleinsäurechemie verwendet wird, insbesondere bei der Synthese von Oligonukleotiden. Diese Substanz weist eine Cytidinbasis auf, die ein Nukleosid ist, das aus einem Pyrimidinring und einem Ribosezucker besteht, modifiziert mit einer Benzoylgruppe und einer Phosphoramiditgruppe. Die Anwesenheit der bis(4-Methoxyphenyl)phenylmethylgruppe verbessert ihre Stabilität und Löslichkeit, wodurch sie für verschiedene biochemische Anwendungen geeignet ist. Die Cyanethylphosphoramiditfunktionalität ermöglicht effiziente Kupplungsreaktionen während der Oligonukleotidsynthese und erleichtert die Bildung von Phosphodiesterbindungen. Diese Verbindung zeichnet sich durch ihre Fähigkeit aus, an selektiven Reaktionen teilzunehmen, was zur Entwicklung synthetischer Methoden in der Molekularbiologie und Gentechnik beiträgt. Ihre CAS-Nummer, 105931-57-5, dient als eindeutiger Identifikator für regulatorische und Forschungszwecke.
Formel:C47H54N5O9P
InChl:InChI=1S/C47H54N5O8P/c1-32(2)52(33(3)4)61(58-28-14-27-48)60-41-29-43(51-30-34(5)44(50-46(51)54)49-45(53)35-15-10-8-11-16-35)59-42(41)31-57-47(36-17-12-9-13-18-36,37-19-23-39(55-6)24-20-37)38-21-25-40(56-7)26-22-38/h8-13,15-26,30,32-33,41-43H,14,28-29,31H2,1-7H3,(H,49,50,53,54)/t41-,42+,43+,61?/m0/s1
InChI Key:InChIKey=AGMUHEZFYUECLW-QUZMAVINSA-N
SMILES:C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
Synonyme:- 4: PN: US20030212017 PAGE: 17 claimed DNA
- 5'-O-(4,4'-Dimethoxytrityl)-5-Methyl-N4-Benzoyl-2'-Deoxycytidine-3'-(2-Cyanoethyl-N,N-Diisopropyl)Phosphoramidite
- 5: PN: US20030211606 PAGE: 17 claimed DNA
- 6: PN: US20040014048 PAGE: 18 claimed DNA
- 6: PN: US20040014049 PAGE: 18 claimed DNA
- 7: PN: US20030198965 PAGE: 17 claimed DNA
- 7: PN: US20040014047 PAGE: 18 claimed DNA
- 80: PN: US20040005707 PAGE: 18 claimed DNA
- 8: PN: US20040005565 PAGE: 17-22 claimed DNA
- 8: PN: US20040005569 PAGE: 20 claimed DNA
- 8: PN: US20040005570 PAGE: 18 claimed DNA
- 8: PN: US20040006029 PAGE: 20 claimed DNA
- 8: PN: US20040006030 PAGE: 20 claimed DNA
- 8: PN: US20040014050 PAGE: 18 claimed DNA
- 8: PN: US20040014051 PAGE: 20 claimed DNA
- 8: PN: US20040014699 PAGE: 18 claimed DNA
- 8: PN: WO03106645 PAGE: 64 claimed DNA
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- N4-Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite
- DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite
- 5'-O-DMT-N4-Benzoyl-2'-Deoxy-5-Methylcytidine-CE Phosphoramidite
- 5-Me-DMT-dC(Bz)-CE
- N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-deoxycytidine-3'-cyanoethyl Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE Phosphoramidite
- 8: PN: US20040014050 PAGE
- 5-methyldeoxycytidine-ce*phosphoramidite for cycl
- 5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite
- US20040006030 PAGE: 20 claimed DNA
- 5'-Dimethoxytrityl-N-benzoyl-5-methyl-2'-deoxyCytidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5-Me-dCBzPhosphoramidite
- deoxy N-Bz 5-Me Cytidine Amidite
- 2'-deoxycytidine-3'-cyanoethyl
- Phosphoramidite
- N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-tetrahydrofuran-2-yl]-5-methyl-2-oxo-pyrimidin-4-yl]benzamide
- N-blocked-5'-O-DMT CED methyldeoxycytidine phosphoramidite
- 5-Me-DMT-dC(Bz)-CE Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
- 5'-O-(4,4'-DiMethoxytrityl)-N4-benzoyl-2'-deoxy-5-Methylcytidine-3'- O-(O-2-cyanoethyl-N,N-diisopropylaMino) phosphoraMidite
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-cytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- DMT-5Me-dC(Bz)-CE Phosphoramidite
- N4-benzoyl-5-methyl-5'-O-(4, 4'-dimethoxytrityl)-
- Bz-5-Me-dC phosphoramidite
- 5-Me Bz dC Beta-Cyanoethyl Phosphoramidite (500 mg) (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
- 5-Me-dC CE Phosphoramidite
- Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
- N -Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl-N,N-diisopropylphosphoramidite(DMT-5-MedC(bz)phosphoramidite)
- Weitere Synonyme anzeigen
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8 Produkte.
5-Me Bz dC β-Cyanoethyl Phosphoramidite (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormel:C47H54N5O8PFarbe und Form:White PowderMolekulargewicht:847.3715'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
CAS:Formel:C47H54N5O8PReinheit:98%Farbe und Form:SolidMolekulargewicht:847.9341DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:DMT-5Me-dC(Bz)-CE PhosphoramiditeReinheit:99%Molekulargewicht:847.93g/molDMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.Formel:C47H54N5O8PFarbe und Form:SolidMolekulargewicht:847.93DMT-5-Me-dC(Bz) Phosphoramidite
CAS:Formel:C47H54N5O8PReinheit:>95.0%(HPLC)Farbe und Form:White to Yellow powder to crystalMolekulargewicht:847.95N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are widely used as building blocks in the chemical synthesis of oligonucleotides. The use of a chemical synthesis rather than an enzymatic one allows bespoke oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with the 5’ hydroxyl of the next nucleoside in the desired sequence. The reaction is usually catalysed by 1H-tetrazole or 4,5-dicyanoimidazole in acetonitrile. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, also called N4-Bz-5'-DMT-5-Me-dC phosphoramidite, is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.</p>Formel:C47H54N5O8PReinheit:Min. 95%Farbe und Form:White PowderMolekulargewicht:847.93 g/mol
