CAS 1092578-46-5

3-((3R,4S)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

CAS: 1092578-46-5

Formel: C₁₆H₂₀N₆O

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 312.3696

Ref: IN-DA008T9A

Tofacitinib Impurity 42

CAS: 1092578-46-5

Formel: C₁₆H₂₀N₆O

Farbe und Form: White To Off-White Solid

Molekulargewicht: 312.38

Ref: 4Z-T-117003

3-((3R,4S)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

CAS: 1092578-46-5

3-((3R,4S)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

Reinheit: 98%

Molekulargewicht: 312.38g/mol

Ref: 54-OR1073772

(3R,4S)-Tofacitinib

Kontrolliertes Produkt

CAS: 1092578-46-5

Applications (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
References Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)

Formel: C₁₆H₂₀N₆O

Farbe und Form: Neat

Molekulargewicht: 312.37

Ref: TR-T528000

(3R,4S)-Tofacitinib-d3

Kontrolliertes Produkt

CAS: 1092578-46-5

Formel: C₁₆D₃H₁₇N₆O

Farbe und Form: Neat

Molekulargewicht: 315.388

Ref: TR-T528002

(3R,4S)-Tofacitinib

CAS: 1092578-46-5

Formel: C₁₆H₂₀N₆O

Molekulargewicht: 312.38

Ref: ST-EA-CP-T23039

Tofacitinib Impurity A

CAS: 1092578-46-5

Formel: C₁₆H₂₀N₆O

Molekulargewicht: 312.38

Ref: ST-EA-CP-T23054

(3R,4S)-Tofacitinib

CAS: 1092578-46-5

(3R,4S)-Tofacitinib is a synthetic compound that is being researched for the treatment of rheumatoid arthritis. It is a potent inhibitor of Janus Kinase 3 (JAK3) and Janus Kinase 1 (JAK1), which are important enzymes in cytokine signaling pathways that play a role in inflammation. (3R,4S)-Tofacitinib is metabolized to an impurity standard for the drug product. The metabolite has not been characterized and its concentration cannot be determined from analytical data.

Formel: C₁₆H₂₀N₆O

Reinheit: Min. 95%

Molekulargewicht: 312.37 g/mol

Ref: 3D-STB57846

(3R,4S)-Tofacitinib

CAS: 1092578-46-5

(3R,4S)-Tofacitinib, the less active enantiomer of Tofacitinib, is a JAK3 inhibitor with an IC50 of 1 nM.

Formel: C₁₆H₂₀N₆O

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 312.37

Ref: TM-T13426