CAS 11061-68-0
:Humaninsulin
Beschreibung:
Humaninsulin, mit der CAS-Nummer 11061-68-0, ist ein Peptidhormon, das von der Bauchspeicheldrüse produziert wird und eine entscheidende Rolle im Glukosestoffwechsel spielt. Es besteht aus 51 Aminosäuren und hat ein Molekulargewicht von etwa 5.800 Dalton. Insulin wirkt hauptsächlich, um die Blutzuckerspiegel zu senken, indem es die Aufnahme von Glukose in die Zellen, insbesondere in Muskel- und Fettgewebe, erleichtert und die hepatische Glukoseproduktion hemmt. Die Struktur von Insulin besteht aus zwei Ketten, A und B, die durch Disulfidbrücken verbunden sind, die für seine biologische Aktivität unerlässlich sind. Insulin wird typischerweise durch Injektion verabreicht, da es aufgrund seiner proteinhaltigen Natur nicht wirksam ist, wenn es oral eingenommen wird, da es im Magen-Darm-Trakt abgebaut wird. Es wird therapeutisch zur Behandlung von Diabetes mellitus eingesetzt und hilft, die Blutzuckerspiegel bei Personen mit Insulinmangel oder -resistenz zu kontrollieren. Humaninsulin wird durch rekombinante DNA-Technologie hergestellt, um eine konsistente und sichere Versorgung für medizinische Zwecke zu gewährleisten.
Formel:C257H383N65O77S6
InChl:InChI=1/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)/t131-,132-,133-,134?,135?,136?,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-,209-/m0/s1
Synonyme:- Insulin, Zinc, Human, Recomb.
Sortieren nach
Reinheit (%)
0
100
|
0
|
50
|
90
|
95
|
100
14 Produkte.
Insulin solution (4mg/mL) [Optimized for Cell Culture]
CAS:Farbe und Form:Colorless to Almost colorlessclear liquidInsulin Human
CAS:Insulin and its saltsFormel:C257H383N65O77S6Farbe und Form:White Lyophilized CakeMolekulargewicht:5803.63765High Molecular Weight Insulin Human
CAS:Insulin and its saltsFormel:C257H383N65O77S6(monomer)Farbe und Form:White Off-White PowderMolekulargewicht:5803.63765Insulin Human, recombinant
CAS:Formel:C257H383N65O77S6Reinheit:95.0 - 105.0 % (dried basis)Farbe und Form:White to off-white powderMolekulargewicht:5807.57Insulin (human)
CAS:Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood.Formel:C257H383N65O77S6Reinheit:97.32% - 99.99%Farbe und Form:SolidMolekulargewicht:5807.57Insulin (Human)
CAS:<p>Applications Insulin (Human) is a peptide hormone regulating the metabolism of carbohydrates and fats. It is used in the treatment of those suffering from the diabetes type I and II metabolic disorders. Regulates the absorption of glucose from the blood to skeletal muscles and fat storage.<br>References Lai, Y. et al.: Biochem. J., 460, 363 (2014); Hedman, C. et al.: Clin. Endocrinol., 81, 58 (2014);<br></p>Formel:C257H383N65O77S6Farbe und Form:NeatMolekulargewicht:5807.57Insulin (Human)
CAS:<p>Insulin is a peptide hormone that regulates the uptake and storage of glucose by muscle and fat cells. Insulin is produced by beta cells in the pancreas, which release it into the bloodstream when blood sugar levels rise. Insulin lowers glucose levels by increasing the amount of glucose taken up from the blood into muscle and fat cells, suppressing hepatic gluconeogenesis, and promoting glycolysis. It also increases protein synthesis, decreases proteolysis, and stimulates growth. With a molecular weight of 5808 Da, insulin is composed of two polypeptide chains with an approximate molecular weight of 3120 Da each linked by disulfide bonds. Insulin has no lipid moiety or carbohydrate moiety.<br>Insulin binds to its receptor on the surface of a cell to trigger one or more signaling cascades leading to changes in metabolism. Binding to the receptor triggers a conformational change in the receptor that causes insulin to be released from its binding site on the receptor.</p>Formel:C257H383N65O77S6Reinheit:Min. 95%Molekulargewicht:5,807.6 g/molInsulin
CAS:Insulin is a hormone that is produced by beta cells in the pancreas and regulates blood sugar levels. It is used for the treatment of diabetes mellitus, a disease in which the body does not produce enough insulin or cannot use insulin properly. Insulin works by lowering the level of glucose (sugar) in the blood, thereby regulating its supply to various parts of the body. Insulin has been shown to be effective at reducing postprandial blood glucose concentrations. This drug also lowers blood glucose concentrations by stimulating glucose uptake into muscle and adipose tissue. Insulin is also used to treat type 1 diabetes, gestational diabetes, and other conditions where low insulin production results in high blood sugar levels.Formel:C257H383N65O77S6Reinheit:Reported (%)Farbe und Form:PowderMolekulargewicht:5,807.57 g/molInsulin (Human)
CAS:<p>Human insulin is a peptide hormone produced by beta cells in the pancreas. The insulin receptor is found on the surface of liver, fat, and muscle cells. When binding to its receptor, insulin opens ion channels allowing potassium ions to flow into the cell and sodium ions to flow out of the cell. This change in ion concentration causes an electrical potential across the membrane that triggers an influx of calcium ions from outside the cell. These changes result in an increase in glucose uptake by tissues and inhibition of glucose production by the liver. Insulin also binds to a secondary receptor called IGF-1R (insulin-like growth factor) which activates intracellular signaling pathways involving PI3K and Akt kinase. Insulin can be used as a research tool for studying protein-protein interactions or as a pharmacological agent for diabetes treatment. <br>This product is enzymatically derived from Porcine Insulin A-chain, available as a 0.5mg vial and contains disulfide bonds between CysA6-CysA11,CysA7-CysB7, and CysA20-CysB19.</p>Formel:C257H383N65O77S6Reinheit:Min. 95%Molekulargewicht:5,807.6 g/molr-Insulin ex. Human for cell culture, 25 USP U/mg, Endotoxin (BET) 1.0EU/mg
CAS:Formel:C257H383N65O77S6Farbe und Form:White, PowderMolekulargewicht:~ 5808Insulin Human (COLD SHIPMENT REQUIRED) (DISCONTINUED)
CAS:Insulin and its saltsFormel:C257H383N65O77S6Farbe und Form:White CrystalsMolekulargewicht:5803.63765
![Insulin solution (4mg/mL) [Optimized for Cell Culture]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FI1257.jpg&w=3840&q=75)
