CAS 112242-17-8

Buprenorphine N-Oxide

Kontrolliertes Produkt

CAS: 112242-17-8

Formel: C₂₉H₄₁NO₅

Farbe und Form: Neat

Molekulargewicht: 483.64

Ref: 86-MM0120.15

Buprenorphine N-oxide

Kontrolliertes Produkt

CAS: 112242-17-8

Applications Prodrug of Buprenorphine, exhibits improved bioavailability

Formel: C₂₉H₄₁NO₅

Farbe und Form: Yellow

Molekulargewicht: 483.64

Ref: TR-B689575

Buprenorphine N-oxide (1 mg/ml in Methanol)

Kontrolliertes Produkt

CAS: 112242-17-8

Formel: C₂₉H₄₁NO₅

Farbe und Form: Single Solution

Molekulargewicht: 483.64

Ref: TR-KIT9785

Buprenorphine N-oxide - 1.0mg/ml in Acetonitrile

Kontrolliertes Produkt

CAS: 112242-17-8

Buprenorphine N-oxide is a metabolite of buprenorphine. It is the major component in human urine, with a concentration of 0.2% to 2%. The elimination of buprenorphine N-oxide has been shown to be slower than that of buprenorphine in humans. Buprenorphine N-oxide is an active metabolite that binds to the same opioid receptors as buprenorphine and norbuprenorphine. This drug has been shown to have similar effects on the human liver as buprenorphine, but it does not cause respiratory depression or sedation. Buprenorphine N-oxide also has been shown to inhibit cytochrome P450 enzymes in the liver microsomes of rats and mice, which may lead to an increase in the rate of elimination of other drugs, such as methadone and propoxyphene, by competing for hepatic metabolism.

Formel: C₂₉H₄₁NO₅

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 483.64 g/mol

Ref: 3D-FB19362