CAS 112471-14-4

N-(Diphenoxymethylene)-methanesulfonamide

Kontrolliertes Produkt

CAS: 112471-14-4

Applications N-(Diphenoxymethylene)-methanesulfonamide is used in the synthesis of analog of ranitidine, N-2-(2-Hydroxy-2-phenyl)ethyl-N’’-(methanesulfonyl)guanidine, which possesses antiulcer activity.Also, it is an intermediate used in the synthesis of Osutidine (O703905), which can be used in the biological study of studies on cAMP generation in hepa cells expressing histamine H2 receptor antagonism by T-593. Anti-ulcer drug that is structurally related to Rantidine (R120000).
References Shibata, H., et al.: Yakugaku Zasshi, 118, 88-104 (1998); Tashiro, T., et al.: Pharmacology, 59, 1 (1999)

Formel: C₁₄H₁₃NO₄S

Farbe und Form: Neat

Molekulargewicht: 291.322

Ref: TR-D489395

N-(Diphenoxymethylene)-methanesulfonamide

CAS: 112471-14-4

N-(Diphenoxymethylene)-methanesulfonamide is a potent cancer kinase inhibitor that has been shown to induce apoptosis in human cancer cells. It is an analog of the anticancer drug staurosporine and inhibits a wide range of kinases, including cyclin-dependent kinases (CDKs) and protein kinase C. N-(Diphenoxymethylene)-methanesulfonamide has demonstrated significant activity against various tumor types in Chinese hamster ovary cells and has been shown to be effective in inhibiting the growth of several different cancer cell lines. This inhibitor can also be found in urine samples, indicating its potential use as a biomarker for cancer diagnosis and treatment monitoring. Overall, N-(Diphenoxymethylene)-methanesulfonamide represents a promising new class of anticancer agents with broad-spectrum kinase inhibition activity.

Formel: C₁₄H₁₃NO₄S

Reinheit: Min. 95%

Molekulargewicht: 291.32 g/mol

Ref: 3D-MEA47114