CAS 114-07-8

Erythromycin

Beschreibung:

Erythromycin ist ein Makrolid-Antibiotikum, das hauptsächlich zur Behandlung von bakteriellen Infektionen eingesetzt wird. Es wird aus dem Bakterium Saccharopolyspora erythraea gewonnen und ist wirksam gegen eine Vielzahl von grampositiven Bakterien und einige gramnegative Bakterien. Die chemische Struktur von Erythromycin weist einen großen Laktonring auf, der für Makrolide charakteristisch ist, sowie mehrere Zuckermoleküle, die zu seiner Löslichkeit und biologischen Aktivität beitragen. Erythromycin wirkt, indem es die bakterielle Proteinsynthese hemmt und somit das Wachstum und die Fortpflanzung von Bakterien verhindert. Es wird häufig zur Behandlung von Atemwegsinfektionen, Hautinfektionen und bestimmten sexuell übertragbaren Infektionen eingesetzt. Erythromycin ist in verschiedenen Formulierungen erhältlich, darunter orale Tabletten, topische Salben und intravenöse Zubereitungen. Obwohl es im Allgemeinen gut vertragen wird, kann es Nebenwirkungen wie gastrointestinale Störungen verursachen und kann aufgrund seiner Auswirkungen auf Leberenzyme mit anderen Medikamenten interagieren. Resistenzen gegen Erythromycin wurden bei einigen bakteriellen Stämmen beobachtet, was seine Wirksamkeit bei bestimmten Infektionen einschränken kann.

Formel: C₃₇H₆₇NO₁₃

InChl: InChI=1/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21?,22-,23+,24+,25-,26+,28-,29?,30?,31+,32?,34?,35-,36-,37-/m1/s1

InChI Key: InChIKey=ULGZDMOVFRHVEP-RWJQBGPGSA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3

Synonyme:

• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl propanoate (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,7R,9R,11R,13S,14R)-6-{[(3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• 6-{[4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• Abboticin
• Abomacetin
• Ak-Mycin
• Aknin
• Dotycin
• Drmysin
• E-Base
• E-mycin
• E.E.S
• EMU
• Emgel
• Ergel
• Eritocina
• Eritrex
• Eritrocina
• Eritromed
• Eritromicina
• Ermycin
• Erthrogran
• Ery Derm
• Ery-Ped
• Ery-Tab
• EryDerm
• Eryacne
• Eryc
• Erycen
• Erycette
• Erycin
• Erycinum
• Erygel
• Erymax
• Erytab
• Erythro
• Erythrocin
• Erythrogran
• Erythroguent
• Erythromast
• Erythromast 36
• Erythromid
• Erythromycin A
• Erythromycine
• Ilocap
• Ilosone
• Ilotycin
• Inderm
• L-alpha-Egg-phosphatidylcholine
• Nsc 55929
• Oxacyclotetradecane, erythromycin deriv.
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• P.C.E.
• PCE
• Pantomicina
• Pediamycin
• Retcin
• Robimycin
• Statcin
• Staticin
• Stiemycin
• T-Stat
• Theramycin Z
• Torlamicina
• Torlamicna
• Vetwic
• Wintrocin
• Wyamycin-s
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• Erythromycin
• ErMysin
• ERYTHROMYCIN STANDARD SOLUTION*
• ERYTHROMYCIN BASE
• ERYTHROMYCIN USP(CRM STANDARD)
• Abomacetin AK-Mycin, Aknin
• Erythromycin,Erythromycinum
• StreptoMyces erythreus
• ERYTHROMYCIN, PH EUR
• em
• ibo-hexopyranosyl)-oxy)-14-ethyl-7,12,13-tr///
• BRAND? volumetric flask BLAUBRAND? USP conformity certified
• (3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)-4-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)oxacyclotetradecane-2,10-dione
• propiocine
• nosyl)-oxy)-6,11,12,13-tetrahydroxy-2,4,6,8///
• Radix Ophiopogonis P.E.
• ERYTHROMYCIN C USP(CRM STANDARD)
• ERYTHROMYCIN.BASERESEARCH GRADE
• ERYTHROMYCIN THICYANATE
• (-)-Erythromycin, Eur.Pharm.
• erythromycin,compdwithmonododecylsulfate,sodiumsalt
• ERYTHROMYCIN WHO(CRM STANDARD)
• ERYTHROMYCIN CELL CULTURE TESTED
• (3R,5R,6S,7R,8R,11R,13R,14R,15S,16R)-7-((2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-16-ethyl-8,14,15-trihydroxy-5-((2R,4S,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yloxy)-3,6,8,11,13,15-hexamethyloxacyclohexadecane-2,12-dione
• ERYTHROMYCIN B USP(CRM STANDARD)
• pentadecanoicacid,3-((2,6-dideoxy-3-c-methyl-3-o-methyl-alpha-l-ribo-hexopyra
• ERYTHROMYCIN, BIOTECHNOLOGY PERFORMANCE
• sulfuricacid,monododecylester,sodiumsalt,compdwitherythromycin
• USP
• ERYTHROMYCIN MIXTURE A,B,C
• BRAND? USP BLAUBRAND? class AS graduated pipette
• ERYTHROMYCIN A EPE(CRM STANDARD)
• BRAND? USP BLAUBRAND? volumetric pipettes, one-mark
• BRAND? USP BLAUBRAND? class A measuring cylinder, tall form
• oxacyclotetradecane-2,10-dione,4-((2,6-dideoxy-3-c-methyl-3-o-methyl-alpha-l-r
• ERYTHROMYCIN 960 I.U./MG EPE(CRM STANDARD)
• BRAND? volumetric flask, USP, BLAUBRAND
• ERYTHROMYCIN PLANT CELL CULTURE TESTED
• Aknemycin
• ErythromycinAlkali
• ERYTHROMYCINUM
• Erythromycin (250 mg)
• ERYTHROMYCIN C*) EPE(CRM STANDARD)
• Erythromycin BasePhosphate & Salts
• ERYTHROMYCIN (90-95% ERYTHROMYCIN A)
• Bulb pipettes
• Erytromycin A
• Erithromycin
• Ilotycin, ErythroMycin
• BRAND? volumetric flask BLAUBRAND? USP 27 conformity certified
• ERYTHROMYCIN,POWDER,USP
• ERYTHROMYCIN C WHO(CRM STANDARD)
• (-)-Erythromycin,98%
• ERYTHROMYCIN, STREPTOMYCES ERYTHREUS
• knin
• ERYTHROMYCIN CELL CULTURE REAGENT
• Erythromycin (base and/or unspecified salts)
• ErythroMycin COS/CGMP
• nci-c55674
• erythromast36
• ERYTHROMYCIN A,B,C
• ERYTHROMYCIN 98%
• ERYTHROMYCIN USP
• erythromycinsodiumlaurylsulfate
• ERYTHROMYCIN 9-OXIME 90+% HPLC
• Erythromycin,E-Mycin, Erythrocin
• BRAND? volumetric flask BLAUBRAND? USP
• ERYTHROMYCIN RELATED COMPOUND NN-DEMETHYLERYTHROMYCIN A USP(CRM STANDARD)
• ERYTHROMYCIN B EPE(CRM STANDARD)
• Erythromycin (mixture of A,B,C)
• Erythromycin-Bp/Ep/Usp

Erythromycin-d3

Kontrolliertes Produkt

CAS: 114-07-8

Applications Isotope labelled Erythromycin (E649950), an antibiotic useful for the treatment of a number of bacterial infection, usually prescribed to patients with allergy to penicillin.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

Formel: C₃₇H₆₄D₃NO₁₃

Farbe und Form: Neat

Molekulargewicht: 736.96

Ref: TR-E649954

Erythromycin

CAS: 114-07-8

Applications Erythromycin is an antibiotic.This compound is a contaminant of emerging concern (CECs).
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

Formel: C₃₇H₆₇NO₁₃

Farbe und Form: White

Molekulargewicht: 733.93

Ref: TR-E649950

Erythromycin

CAS: 114-07-8

A broad-spectrum antibiotic of macrolide class, which targets 50S ribosomal subunit and inhibits protein synthesis. Erythromycin is widely used in molecular biology and biotechnology as a selection marker. Erythromycin is also an agonist of the motilin receptor, and it has prokinetic activity on the gut.

Formel: C₃₇H₆₇NO₁₃

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 733.93 g/mol

Ref: 3D-AE22796

Erythromycin for tissue culture

CAS: 114-07-8

Formel: C₃₇H₆₇NO₁₃

Farbe und Form: White to off - white, Hygroscopic powder, Clear, Colourless

Molekulargewicht: 733.93

Ref: SR-48535

Erythromycin, Antibiotic for Culture Media Use Only

CAS: 114-07-8

Erythromycin, Antibiotic for Culture Media Use Only, is a macrolide antibiotic derived from the bacterium *Saccharopolyspora erythraea*. It functions by inhibiting protein synthesis, specifically targeting the 50S ribosomal subunit in susceptible bacteria. This action results in the prevention of peptide chain elongation, effectively halting bacterial growth and proliferation.

Formel: C₃₇H₆₇NO₁₃

Reinheit: Min. 93.0 Area-%

Molekulargewicht: 733.93 g/mol

Ref: 3D-E-3250

Erythromycin A

CAS: 114-07-8

Erythromycin A

Formel: C₃₇H₆₇NO₁₃

Reinheit: 96.7%

Farbe und Form: White

Molekulargewicht: 733.46124

Ref: 47-794