CAS 114601-31-9

3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbonitrile (Temozolomide Impurity)

CAS: 114601-31-9

3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbonitrile (Temozolomide Impurity)

Reinheit: 98%

Ref: 54-OR1036728

Temozolomide EP Impurity C

CAS: 114601-31-9

Formel: C₆H₄N₆O

Farbe und Form: Off-White Solid

Molekulargewicht: 176.14

Ref: 4Z-T-346

8-Descarboxamido-8-cyanotemozolomide (3,4-Dihydro-3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carbonitrile)

Kontrolliertes Produkt

CAS: 114601-31-9

Formel: C₆H₄N₆O

Farbe und Form: Neat

Molekulargewicht: 176.14

Ref: 86-MM1480.06

8-Descarboxamido-8-cyano Temozolomide

Kontrolliertes Produkt

CAS: 114601-31-9

Applications 8-Descarboxamido-8-cyano Temozolomide is a useful synthetic intermediate in the synthesis of Temozolomide (T017775); an imidazotetrazine alkylating agent and antineoplastic.
References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)

Formel: C₆H₄N₆O

Farbe und Form: Light Yellow To Light Brown

Molekulargewicht: 176.14

Ref: TR-D290810

8-Descarboxamido-8-cyano temozolomide

CAS: 114601-31-9

Temozolomide is an organic compound with a nitro group at the 8-position. It is used as a cytotoxic agent to treat cancer. Temozolomide has been shown to yield high yields of up to 98% when synthesized in acidic conditions, such as hydrochloric acid and methyl isocyanate. This compound can also be synthesized in basic ph conditions using carbamate chemistry. The sensitivity of this compound to nitrophenyl, nitrite, and chloride can be used to determine its purity. Organic synthesis of temozolomide requires an understanding of organic chemistry principles and the use of basic laboratory equipment such as a vacuum pump, a glassware set, and a drying oven.

Formel: C₆H₄N₆O

Reinheit: Min. 95%

Molekulargewicht: 176.14 g/mol

Ref: 3D-PEA60131

Temozolomide EP Impurity C

CAS: 114601-31-9

Formel: C₆H₄N₆O

Molekulargewicht: 176.14

Ref: ST-EA-CP-T15003