
CAS 1159613-24-7
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4 Produkte.
3’-Hydroxy Darunavir
CAS:Formel:C27H37N3O8SFarbe und Form:White To Off-White SolidMolekulargewicht:563.673?-Hydroxy Darunavir
CAS:Kontrolliertes Produkt<p>Applications 3’-Hydroxy Darunavir is a metabolite of Darunavir (D193500), a novel inhibitor of human immunodeficiency virus protease and used in the treatment of HIV infection. It is a COVID19-related research product.<br>References Vermeir, M., et al.: Drug. Meta. Disp., 37, 809 (2009); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),<br></p>Formel:C27H37N3O8SFarbe und Form:NeatMolekulargewicht:563.663-Hydroxy darunavir
CAS:<p>3-Hydroxy darunavir is a prodrug. It is hydrolyzed to its active form, darunavir, in the liver by esterases. 3-Hydroxy darunavir binds to the peptide receptor CXCR4 and inhibits HIV from entering the cell. 3-Hydroxy darunavir has also been shown to inhibit ion channels and Ligand-gated ion channels, which are important for neurotransmission. This drug is used as a research tool for Cell Biology and as an inhibitor of ion channels.</p>Formel:C27H37N3O8SReinheit:Min. 95%Molekulargewicht:563.7 g/mol



