CAS 117399-93-6

Endothelin 3

Beschreibung:

Endothelin-3 (ET-3) ist ein potentes vasokonstriktorisches Peptid, das eine bedeutende Rolle in verschiedenen physiologischen Prozessen spielt, einschließlich der vaskulären Homöostase und der Regulierung des Blutdrucks. Es gehört zur Familie der Endothelinen, die aus drei Isoformen besteht: Endothelin-1, Endothelin-2 und Endothelin-3. ET-3 wird hauptsächlich von Endothelzellen produziert und hat eine hohe Affinität zu Endothelinrezeptoren, insbesondere zu den ETA- und ETB-Rezeptoren, die G-Protein-gekoppelte Rezeptoren sind. Dieses Peptid besteht aus 21 Aminosäuren und zeichnet sich durch seine Fähigkeit aus, die Kontraktion der glatten Muskulatur zu induzieren und die Zellproliferation zu beeinflussen. Neben seinen kardiovaskulären Effekten ist Endothelin-3 an der Regulierung der Nierenfunktion beteiligt und hat Auswirkungen auf verschiedene pathologische Zustände, einschließlich Bluthochdruck und Herzinsuffizienz. Seine Synthese und Freisetzung können durch verschiedene Faktoren beeinflusst werden, einschließlich Hypoxie und entzündliche Zytokine. Insgesamt ist Endothelin-3 ein kritischer Mediator im Endothelin-Signalweg mit unterschiedlichen biologischen Effekten in verschiedenen Geweben.

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Synonyme:

• Endothelin-3,Human
• H-Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-Oh
• Endothelin-3 (Human, Mouse, Rabbit, Rat)
• Endothelin-3 (Human) (Porcine, Rat, Rabbit)
• Endothelin-3 (Human, Rat, Pig)
• Endothelin-3 (Human, Rat, Porcine, Rabbit)
• Endothelin 3, human, rat, ≥97% (HPLC), powder
• Human endothelin-3
• 33,34,49,50-Tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontane, cyclic peptide deriv.
• Endothelin 3 (Rat,Human)
• CTCFTYKDKECVYYCHLDIIW
• CTCFTYKDKECVYYCHLDIIW (DISULFIDE BRIDGE: 1-15 AND 3-11)
• Endothelin 3【rabbit】
• Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem
• et-3
• Anti-EDN3 antibody produced in rabbit
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP
• human,rat
• ET-3 (huMan, Mouse, rabbit, rat)
• H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP
• Endothelin 3 (huMan)(9CI)
• Endothelin 3 (mouse intestine)
• ET-3 (HUMAN, MOUSE, RABBIT, RAT)
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR- TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11)
• ENDOTHELIN-3
• Rat endothelin-3
• ENDOTHELIN-III, HUMAN, RAT
• Endothelin 3 huMan, ratEndothelin
• ENDOTHELIN 3 HUMAN, RAT
• L-Tryptophan, L-cysteinyl-L-threonyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-, cyclic (1→15),(3→11)-bis(disulfide)
• ANTI-EDN3 (C-TERM) antibody produced in rabbit
• Endothelin 3【rat】
• ENDOTHELIN 3, HUMAN, RAT, 50 UG*
• ET-3 (HUMAN, RAT)
• ET-3 (HUMAN, RAT, PIG)
• M.W. 2643.04 C121H168N26O33S4
• Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11)
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP HUMAN, RAT, PORCINE, RABBIT
• EDN3
• Endothelin 3【canine】
• ET-3, HUMAN AND RAT
• CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP: CTCFTYKDKECVYYCHLDIIW DISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11
• 19: PN: WO2007112069 SEQID: 10 claimed protein
• ET-3, HUMAN
• ENDOTHELIN 3, HUMAN AND RAT
• H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11)

Endothelin-3, Human

CAS: 117399-93-6

For cellular and molecular biology applications

Farbe und Form: White to off-white, Lyophilized Powder

Ref: 02-J66312

Endothelin-3 (human, mouse, rabbit, rat)

CAS: 117399-93-6

ET-1, ET-2, and ET-3 are the products of three distinct endothelin genes. ET-2 and ET-3 are similar to ET-1, but differ in two and six amino acids, respectively. All three isopeptides produce strong in vitro vasoconstrictor and in vivo pressor responses. However, the quantitative profiles of their pharmacological activities vary greatly.

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: 93.7%

Farbe und Form: White Lyophilisate

Molekulargewicht: 2643.08

Ref: 01-4013291

Endothelin-3 (human, mouse, rabbit, rat)

CAS: 117399-93-6

Potent constrictor of rat blood vessels in vitro and an effective pressor agent in vivo. Endothelin-3 (ET-3) has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. ET-3 displays selectivity for the ETC receptor.

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: 95.0%

Farbe und Form: White

Molekulargewicht: 2643.08

Ref: 01-4095915

H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH

CAS: 117399-93-6

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: 95%

Farbe und Form: Solid

Molekulargewicht: 2643.0430

Ref: IN-DA008RJ5

Endothelin-3, human, mouse, rabbit, rat

CAS: 117399-93-6

Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 2643.04

Ref: TM-TP1175

Endothelin-3 (human, mouse, rabbit, rat) acetate

CAS: 117399-93-6

Acetate salt

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄•(C₂H₄O₂)x

Reinheit: Min. 95%

Molekulargewicht: 2,643.05 g/mol

Ref: 3D-FE110371

(3S)-3-[[(2S)-2-[[(2S)-2-[[(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-7,13-bis(4-aminobutyl)-22-benzyl-4-(2 -carboxyethyl)-10-(carboxymethyl)-19,28-bis[(1R)-1-hydroxyethyl]-16,39,42-tris[(4-hydroxyphenyl)methyl]-3,6,9,12,15,18,21,

CAS: 117399-93-6

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Molekulargewicht: 2,643.1 g/mol

Ref: 3D-PP50516

Endothelin-3 (Human)

CAS: 117399-93-6

Endothelin-3 (ET-3) is a protein that belongs to the large family of endothelin peptides which activate the G-protein coupled receptors ETA and ETB. However ET-3 has lower affinity for the ETA receptors compared to Endothelin-1 (ET-1) and Endothelin-2 (ET-2), whereas all three endothelins have similar affinity for ETB receptors. As ETB receptors make up around 90% of the endothelin receptors found in the cerebral cortex in humans, ET-3 can be nicknamed the ‘brain endothelin’. Also through ET-3’s activation of ETB receptors, ET-3 is involved in the development of the enteric nervous system which controls within the gut, blood flow, secretion and intestinal motility. This product has disulfide bonds between Cys1-Cys and Cys3-Cys11, is sourced from Porcine, Rat and Rabbit and is available as a 0.5mg vial

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: Min. 95%

Molekulargewicht: 2,643 g/mol

Ref: 3D-PED-4199-V

Endothelin-3 (Human)

CAS: 117399-93-6

Endothelin-3 (ET-3) is a protein that belongs to the large family of endothelin peptides which activate the G-protein coupled receptors ETA and ETB. However ET-3 has lower affinity for the ETA receptors compared to Endothelin-1 (ET-1) and Endothelin-2 (ET-2), whereas all three endothelins have similar affinity for ETB receptors. As ETB receptors make up around 90% of the endothelin receptors found in the cerebral cortex in humans, ET-3 can be nicknamed the ‘brain endothelin’. Also through ET-3’s activation of ETB receptors, ET-3 is involved in the development of the enteric nervous system which controls within the gut, blood flow, secretion and intestinal motility. This product has disulfide bonds between Cys1-Cys and Cys3-Cys11, is sourced from Porcine, Rat and Rabbit and is available as a 0.1mg vial. It can be use as a research tool for studying the function of endothelin receptors.

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: Min. 95%

Molekulargewicht: 2,643 g/mol

Ref: 3D-PED-4199-S

Endothelin 3, human, rat

CAS: 117399-93-6

Custom research peptide; min purity 95%.

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: Min. 95%

Molekulargewicht: 2,643.1 g/mol

Ref: 3D-PE16957

Endothelin-3 (human, mouse, rabbit, rat) trifluoroacetate salt

CAS: 117399-93-6

Trifluoroacetate salt

Formel: C₁₂₁H₁₆₈N₂₆O₃₃S₄

Reinheit: Min. 95%

Molekulargewicht: 2,643.05 g/mol

Ref: 3D-FE110256