CAS 1204178-50-6

ASP3662

CAS: 1204178-50-6

ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.

Formel: C₁₉H₁₆ClF₃N₄O₂

Farbe und Form: Solid

Molekulargewicht: 424.8

Ref: TM-T71243

ASP 3662

CAS: 1204178-50-6

Inhibits 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1), an enzyme required for the intracellular regeneration of glucocorticoids in the CNS. ASP 3662 is selective over 11β-HSD2 and is CNS-penetrant. Reduces chronic pain by maintaining high levels of inactive glucocorticoids and thus demonstrates its anti-nociceptive and analgesic protperties. A potential candidate for the treatment of neuropathic and dysfunctional pain.

Formel: C₁₉H₁₆ClF₃N₄O₂

Reinheit: Min. 95%

Molekulargewicht: 424.8 g/mol

Ref: 3D-BA167526