CAS 1207454-56-5

LT-673

CAS: 1207454-56-5

Formel: C₁₉H₁₄F₂N₆O

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 380.3509

Ref: IN-DA008WLG

BMN 673-13C,15N2

Kontrolliertes Produkt

CAS: 1207454-56-5

Formel: CC₁₈H₁₄F₂₁₅N₂N₄O

Farbe und Form: Neat

Molekulargewicht: 383.33

Ref: TR-B595898

BMN 673-d4

Kontrolliertes Produkt

CAS: 1207454-56-5

Formel: C₁₉D₄H₁₀F₂N₆O

Farbe und Form: Neat

Molekulargewicht: 384.375

Ref: TR-B595897

BMN 673

Kontrolliertes Produkt

CAS: 1207454-56-5

Formel: C₁₉H₁₄F₂N₆O

Farbe und Form: Neat

Molekulargewicht: 380.351

Ref: TR-B595895

(rac)-Talazoparib

CAS: 1207454-56-5

(rac)-Talazoparib ((rac)-BMN-673) (Compound 47) is an orally active inhibitor of PARP1/2, with Ki values of 1.2 nM and 0.87 nM, respectively. It inhibits cellular PARylation at an EC50 of 2.51 nM. This compound leads to the accumulation of DNA damage and suppresses the proliferation of BRCA1/2-mutated MX-1 and Capan-1 cells, with IC50 values of 0.3 nM and 5 nM, respectively. Additionally, (rac)-Talazoparib exhibits antitumor activity in mouse models.

Formel: C₁₉H₁₄F₂N₆O

Farbe und Form: Solid

Molekulargewicht: 380.351

Ref: TM-T204239