CAS 1207751-75-4

MK-5204

CAS: 1207751-75-4

MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.

Formel: C₄₀H₆₅N₅O₅

Farbe und Form: Solid

Molekulargewicht: 695.99

Ref: TM-T38594

MK-5204

CAS: 1207751-75-4

MK-5204 is a novel antifungal agent that has been shown to have broad-spectrum activity in vitro and in vivo against various human fungal pathogens, including Aspergillus fumigatus. The compound is a carboxamide derivative with an isopropyl group at the C2 position and a triazole at the C3 position. It has been shown to be orally active against murine Candida albicans infection. The structural modifications are designed to increase solubility, reduce toxicity, and improve pharmacokinetics. MK-5204 has completed the first phase of clinical development and is currently undergoing optimization for oral administration.
MK-5204 is being developed by Merck Research Laboratories.

Reinheit: Min. 95%

Ref: 3D-BM178545