CAS 1216711-61-3

Homo Sildenafil-d5

Kontrolliertes Produkt

CAS: 1216711-61-3

Applications A new labelled analogue of Sildenafil (S435000).
References Koh, H., et al.: Drug Saf., 23, 351 (2000), Daraghmeh, N., et al.: J. Pharm. Biomed. Anal., 25, 483 (2001), Tseng, M., et al.: J. Food Drug Anal., 10, 112 (2002), Gratz, S., et al.: J. Pharm. Biomed. Anal., 36, 525 (2004),

Formel: C₂₃H₂₇D₅N₆O₄S

Farbe und Form: Neat

Molekulargewicht: 493.63

Ref: TR-H615152

Homo sildenafil-d5

CAS: 1216711-61-3

Sildenafil is the active ingredient in a prescription drug called Viagra. It is an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5) and it is used to treat erectile dysfunction. Sildenafil has been shown to be metabolized by CYP3A4 and CYP2C9 into N-desmethylsildenafil, which has lower affinity for PDE5 than sildenafil. The metabolism of sildenafil can also be inhibited by drugs that inhibit either CYP3A4 or CYP2C9, such as erythromycin, ketoconazole, and grapefruit juice.

Formel: C₂₃H₂₇D₅N₆O₄S

Reinheit: Min. 95%

Molekulargewicht: 493.63 g/mol

Ref: 3D-RYB71161