CAS 122619-90-3

O-Desacetyl Diltiazem N-Oxide

CAS: 122619-90-3

Formel: C₂₀H₂₄N₂O₄S

Molekulargewicht: 388.48

Ref: 4Z-D-0725

Deacetyl Diltiazem N-Oxide

Kontrolliertes Produkt

CAS: 122619-90-3

Applications A metabolite of Diltiazem (D460620).`
References Maizels, M., et al.: Anal. Chem., 73, 5436 (2001), Marquet, P., et al.: Ther. Drug Monit., 24, 255 (2002),

Formel: C₂₀H₂₄N₂O₄S

Farbe und Form: Neat

Molekulargewicht: 388.48

Ref: TR-D198935

Deacetyl diltiazem N-oxide

CAS: 122619-90-3

Deacetyl diltiazem N-oxide (DANO) is a prodrug of diltiazem. It is metabolized to produce the active form of diltiazem, which has been shown to be effective in treating hypertension and angina pectoris. DANO is rapidly absorbed after oral administration and converted to the active form within minutes. The conversion of DANO to diltiazem does not have any effect on its bioavailability or pharmacokinetics. The pharmacokinetic profile of DANO differs from that of the parent drug, with a higher plasma concentration at an earlier time point. This difference may be due to the presence of human metabolites, which are present at a much lower concentration than those found in humans.

Formel: C₂₀H₂₄N₂O₄S

Reinheit: Min. 95%

Molekulargewicht: 388.48 g/mol

Ref: 3D-FD20824

Diltiazem N-Oxide O-Desacetyl Impurity

CAS: 122619-90-3

Formel: C₂₀H₂₄N₂O₄S

Molekulargewicht: 388.5

Ref: ST-EA-CP-D22020