CAS 1260178-87-7

Fluvastatin-d7 Sodium Salt

Kontrolliertes Produkt

CAS: 1260178-87-7

Applications Fluvastatin-d7 Sodium Salt is a labeled synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)

Formel: C₂₄H₁₈D₇FNNaO₄

Farbe und Form: Neat

Molekulargewicht: 440.49

Ref: TR-F601254

Fluvastatin-d7 sodium

CAS: 1260178-87-7

Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid. Deuterated Fluvastatin is a useful tool for research.

Formel: C₂₄H₂₅FNNaO₄

Reinheit: Min. 95%

Molekulargewicht: 442.5 g/mol

Ref: 3D-KAC17887