CAS 1352286-61-3

NCATS-SM4420

CAS: 1352286-61-3

NCATS-SM4420 (Compound A35) is an orally effective ligand for the thyroid-stimulating hormone receptor (TSHR) that inhibits the proliferation of MDA-T32 and MDA-T85 cells both in vitro and in vivo, with IC50 values of 0.71 μM and 0.38 μM, respectively. Additionally, it suppresses the metastasis of MDA-T85F1 in mice. NCATS-SM4420 holds potential for research in the field of thyroid cancer.

Formel: C₃₁H₂₇N₃O₅

Farbe und Form: Solid

Molekulargewicht: 521.56

Ref: TM-T200723