CAS 1358617-36-3

N-(3-Chloro-4-fluorophenyl)-1-[2-(3-methylphenyl)-4-pyrimidinyl]-4-piperidinecarboxamide

Formel: C₂₃H₂₂ClFN₄O

Synonyme:

• N-(3-Chloro-4-fluorophenyl)-1-[2-(3-methylphenyl)-4-pyrimidinyl]-4-piperidinecarboxamide
• BC-1901S

BC-1901S

CAS: 1358617-36-3

BC-1901S functions as a proteasome-independent activator and stabilizer of NRF2. By binding to DCAF1 (E3 ligase subunit), it disrupts the NRF2/DCAF1 interaction and activates NRF2 through the inhibition of NRF2 ubiquitination, independent of KEAP1. BC-1901S has demonstrated anti-inflammatory effects in a murine model of LPS-induced acute lung injury.

Formel: C₂₃H₂₂ClFN₄O

Farbe und Form: Solid

Molekulargewicht: 424.90

Ref: TM-T87995