CAS 14003-96-4

2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-4-methyl-2-oxo-

CAS: 14003-96-4

Formel: C₁₁H₈O₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 204.1788

Ref: IN-DA001BYN

4μ8C

CAS: 14003-96-4

4μ8C

Reinheit: 99%

Molekulargewicht: 204.18g/mol

Ref: 54-OR1023959

4μ8C

CAS: 14003-96-4

4μ8C

Reinheit: ≥95%

Molekulargewicht: 204.18g/mol

Ref: 54-BUP13207

4μ8C

CAS: 14003-96-4

Formel: C₁₁H₈O₄

Reinheit: >95.0%(T)(HPLC)

Farbe und Form: White to Light yellow powder to crystal

Molekulargewicht: 204.18

Ref: 3B-M3735

4μ8C

CAS: 14003-96-4

4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.

Formel: C₁₁H₈O₄

Reinheit: 97.48% - 98.45%

Farbe und Form: Solid

Molekulargewicht: 204.18

Ref: TM-T6363

7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

CAS: 14003-96-4

7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde is an activated molecule that exhibits significant cytotoxicity to human liver cancer cells. It inhibits the mitochondrial membrane potential, leading to the release of cytochrome c and apoptosis induction. 7HMOCA has been shown to be a reactive molecule with benzimidazole derivative properties. This compound depletes cellular glutathione levels and increases intracellular reactive oxygen species (ROS) levels, which leads to DNA fragmentation, cell cycle arrest, and ultimately apoptosis induction when combined with other agents. The fluorescence properties of this molecule have enabled its detection in living cells without the need for additional reagents or labeling.

Formel: C₁₁H₈O₄

Reinheit: Min. 95 Area-%

Farbe und Form: White Powder

Molekulargewicht: 204.18 g/mol

Ref: 3D-FH117553

7-hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

CAS: 14003-96-4

Formel: C₁₁H₈O₄

Reinheit: ≥98%(HPLC)

Molekulargewicht: 204.181

Ref: 10-F366810

8-Formyl-4-methylumbelliferone

Kontrolliertes Produkt

CAS: 14003-96-4

Applications 8-Formyl-4-methylumbelliferone is an inhibitor that blocks substrate access to the active site of IRE1 and selectively inactivates both Xbp1 splicing and IRE1-mediated mRNA degradation.
References Cross, B.C.S., et. al.: Proc. Natl. Acad. Sci. USA, 109, E869 (2012)

Formel: C₁₁H₈O₄

Farbe und Form: Neat

Molekulargewicht: 204.18

Ref: TR-F700835