CAS 142439-99-4

4-Methylumbelliferyl-7-(6-sulfo-2-*acetamido-2-de

Beschreibung:

4-Methylumbelliferyl-7-(6-sulfo-2-acetamido-2-deoxy-α-D-glucopyranosid), allgemein als fluorogenes Substrat bezeichnet, ist eine chemische Verbindung, die hauptsächlich in biochemischen Tests verwendet wird, insbesondere zur Detektion spezifischer Enzyme. Diese Verbindung weist eine Methylumbelliferyl-Gruppe auf, die für ihre fluoreszierenden Eigenschaften bekannt ist und eine empfindliche Detektion ermöglicht, wenn sie von Enzymen wie Glykosidasen gespalten wird. Die Anwesenheit einer Sulfonatgruppe erhöht die Löslichkeit in wässrigen Lösungen, was sie für verschiedene biologische Anwendungen geeignet macht. Darüber hinaus trägt die Acetamidgruppe zur Stabilität und Spezifität des Substrats bei. Die Verbindung wird typischerweise in Forschungseinrichtungen verwendet, um die Kinetik und Aktivität von Enzymen zu untersuchen, und bietet ein wertvolles Werkzeug zum Verständnis des Kohlenhydratstoffwechsels und verwandter biochemischer Wege. Ihre fluoreszierende Natur ermöglicht die Echtzeitüberwachung enzymatischer Reaktionen, was sie zu einem wesentlichen Reagenz in der Molekularbiologie und Biochemie macht. Eine ordnungsgemäße Handhabung und Lagerbedingungen sind erforderlich, um ihre Integrität und Wirksamkeit in experimentellen Anwendungen zu erhalten.

Formel: C₁₈H₂₀NNaO₁₁S

InChl: InChI=1/C18H21NO11S.Na/c1-8-5-14(21)29-12-6-10(3-4-11(8)12)28-18-15(19-9(2)20)17(23)16(22)13(30-18)7-27-31(24,25)26;/h3-6,13,15-18,22-23H,7H2,1-2H3,(H,19,20)(H,24,25,26);/q;+1/p-1/t13-,15-,16-,17-,18-;/m1./s1

SMILES: Cc1cc(=O)oc2cc(ccc12)OC1C(C(C(C(COS(=O)(=O)O)O1)O)O)N=C(C)O.[Na]

Synonyme:

• sodium [(2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methyl sulfate

4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside 6-sulphate sodium salt

CAS: 142439-99-4

Formel: C₁₈H₂₀NNaO₁₁S

Molekulargewicht: 481.40

Ref: 7W-GC5948

4-Methylumbelliferyl-2-acetamido-2-deoxy-6-sulphate-β-D-glucopyranoside sodium salt

CAS: 142439-99-4

4-Methylumbelliferyl-2-acetamido-2-deoxy-6-sulphate-β-D-glucopyranoside sodium salt

Formel: C₁₈H₂₀NO₁₁S·Na

Reinheit: 99% (by tlc) (Typical Value in Batch COA)

Farbe und Form: off white powder

Molekulargewicht: 481.41g/mol

Ref: 54-BIM1189

4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide-6-sulfate, sodium salt

CAS: 142439-99-4

4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.

Formel: C₁₈H₂₀NNaO₁₁S

Reinheit: Min. 98.0 Area-%

Molekulargewicht: 481.41 g/mol

Ref: 3D-M-5505

4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside-6-sulfate sodium salt

CAS: 142439-99-4

4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.

Formel: C₁₈H₂₀NO₁₁SNa

Reinheit: Min. 98 Area-%

Farbe und Form: White Powder

Molekulargewicht: 481.41 g/mol

Ref: 3D-EM03271

4-Methylumbelliferyl 2-Acetamido-2-deoxy-b-D-glucopyranoside 6-Sulphate Sodium Salt

Kontrolliertes Produkt

CAS: 142439-99-4

Applications 4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside 6-sulphate sodium salt is a fluorescent substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (Hexosaminidase A). It can also be used in biological study of characterization of the mutant β-subunit of β-hexosaminidase for dimer formation responsible for the adult form of Sandhoff disease with the motor neuron disease phenotype.
References Yamada, K., et al.: J Biochem, 153, 111 (2013)

Formel: C₁₈H₂₁NO₁₁S·Na

Farbe und Form: Neat

Molekulargewicht: 482.41

Ref: TR-M337660