CAS 1463-10-1

5-Methyluridin

Beschreibung:

5-Methyluridin, auch bekannt als Ribothymidin, ist ein Nukleosid, das aus der Pyrimidinbase Uracil besteht, mit einer Methylgruppe, die an der 5-Position des Uracilrings angebracht ist. Diese Modifikation verbessert die Stabilität und Funktionalität von RNA-Molekülen, insbesondere im Kontext von tRNA, wo sie eine Rolle bei der korrekten Faltung und Funktion des Moleküls spielt. Die chemische Formel von 5-Methyluridin ist C10H13N2O5, und es ist gekennzeichnet durch seine Fähigkeit, an Wasserstoffbrückenbindungen teilzunehmen, aufgrund der Anwesenheit von Hydroxyl- und Aminogruppen. Diese Verbindung ist in Wasser löslich und weist einen relativ niedrigen Schmelzpunkt auf. 5-Methyluridin ist von Interesse in der biochemischen Forschung und hat potenzielle Anwendungen in den Bereichen Molekularbiologie und Pharmakologie, insbesondere in der Untersuchung von RNA-Modifikationen und deren Auswirkungen auf die Genexpression und die Proteinsynthese. Seine CAS-Nummer, 1463-10-1, wird zur Identifizierung in chemischen Datenbanken und regulatorischen Kontexten verwendet.

Formel: C₁₀H₁₄N₂O₆

InChl: InChI=1/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6+,7?,9-/m1/s1

InChI Key: InChIKey=DWRXFEITVBNRMK-JXOAFFINSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(C)=C2

Synonyme:

• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosylthymine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Me-U
• 5-Methyl-Uridine
• 5-methyl-1-(beta-L-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-[(2xi)-beta-D-threo-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• Ribosylthymine
• Ribothymidine
• Thymine riboside
• Uridine, 5-methyl-
• β-<span class="text-smallcaps">D</span>-Ribofuranoside, thymine-1
• 5-Methyluridine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-ribofuranosyl-
• 5-methyuridine
• BETA-RIBOFURANOSIDE
• ribosylthymine/5-methyluridine
• 1-(BETA-D-RIBOFURANOSYL)THYMINE
• 1-β-D-Ribofuranosylthymine
• 5-methyluridine/ribothymidine
• 5-METHYL-D-URIDINE
• 5-Methyluridine (Patent )
• 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
• 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• Methyluridine
• 5-methyl-uridin
• THYMINERIBOSIDE
• BETA-D-THYMINE RIBOSIDE
• 1-(BETA-D-RIBOFURANOSYL)THYMIDINE

5-Methyluridine

CAS: 1463-10-1

Formel: C₁₀H₁₄N₂O₆

Reinheit: >98.0%(T)(HPLC)

Farbe und Form: White to Almost white powder to crystal

Molekulargewicht: 258.23

Ref: 3B-M1405

5-Methyluridine, 99%

CAS: 1463-10-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formel: C₁₀H₁₄N₂O₆

Reinheit: 99%

Molekulargewicht: 258.23

Ref: 02-H64259

Uridine, 5-methyl-

CAS: 1463-10-1

Formel: C₁₀H₁₄N₂O₆

Reinheit: 95%

Farbe und Form: Solid

Molekulargewicht: 258.2280

Ref: IN-DA001DVT

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Reinheit: ≥98%

Molekulargewicht: 258.23g/mol

Ref: 54-BUP18363

5-Methyluridine

CAS: 1463-10-1

Formel: C₁₀H₁₄N₂O₆

Molekulargewicht: 258.23

Ref: 7W-GE5148

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Formel: C₁₀H₁₄N₂O₆

Reinheit: 97%

Farbe und Form: white solid

Molekulargewicht: 258.23g/mol

Ref: 54-OR52639

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine, a methylated nucleoside in human fluids, is higher in tumor patients; targeted by hypomethylating drugs in cancer therapy.

Formel: C₁₀H₁₄N₂O₆

Reinheit: 99.72%

Farbe und Form: Solid

Molekulargewicht: 258.23

Ref: TM-T5282

5-Methyluridine

CAS: 1463-10-1

Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),

Formel: C₁₀H₁₄N₂O₆

Farbe und Form: Neat

Molekulargewicht: 258.23

Ref: TR-M338190

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. It is also used for the treatment of cancer, infectious diseases, and other conditions. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus. The inhibition of cellular proliferation is due to a lack of dna synthesis and RNA synthesis. This nucleoside has been shown to have inhibitory properties against mouse tumor cells grown in vitro, as well as the wild-type strain grown in vivo. 5-Methyluridine may be useful for the treatment of cancer tissues because it can suppress the growth of tumors by inhibiting their ability to replicate.

Formel: C₁₀H₁₄N₂O₆

Reinheit: Min. 98 Area-%

Farbe und Form: White Powder

Molekulargewicht: 258.23 g/mol

Ref: 3D-NM04922

5-Methyluridine

CAS: 1463-10-1

Formel: C₁₀H₁₄N₂O₆

Reinheit: 95%

Farbe und Form: Solid, White to almost white crystal powder

Molekulargewicht: 258.23

Ref: 10-F212233

5-Methyluridine extrapure, 98%

CAS: 1463-10-1

Formel: C₁₀H₁₄N₂O₆

Reinheit: min. 98%

Farbe und Form: White to off - white, Crystalline powder, Clear, Colourless

Molekulargewicht: 258.23

Ref: SR-77337

5-Methyluridine

CAS: 1463-10-1

Formel: C₁₀H₁₄N₂O₆

Molekulargewicht: 258.23

Ref: ST-EA-CP-Z6011