CAS 1486466-31-2

CLOBETASOL IMPURITY J CRS

CAS: 1486466-31-2

CLOBETASOL IMPURITY J CRS

Ref: 41-Y0000571

Clobetasol Propionate Related Compound A (9α-Fluoro-11β-hydroxy-16β-methyl 3-oxo-androsta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one])

CAS: 1486466-31-2

Compounds containing an unfused furan ring, whether or not hydrogenated, in the structure, nesoi

Formel: C₂₅H₃₀ClFO₄

Farbe und Form: White Powder

Molekulargewicht: 448.18167

Ref: 45-1138427

Clobetasol Propionate EP Impurity J (Clobetasol Propionate USP Related Compound A)

CAS: 1486466-31-2

Formel: C₂₅H₃₀ClFO₄

Farbe und Form: White To Off-White Solid

Molekulargewicht: 448.96

Ref: 4Z-C-101015

(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione

CAS: 1486466-31-2

Farbe und Form: Neat

Ref: 86-MM0769.09

9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one

CAS: 1486466-31-2

Impurity Clobetasol Propionate EP Impurity J
Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.
References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),

Formel: C₂₅H₃₀ClFO₄

Farbe und Form: Neat

Molekulargewicht: 448.95

Ref: TR-F591800

Clobetasol Propionate EP Impurity J

CAS: 1486466-31-2

Formel: C₂₅H₃₀ClFO₄

Molekulargewicht: 448.96

Ref: ST-EA-CP-C81023

(17R)-4-Chloro-5-ethyl-9-fluoro-11b-hydroxy-16b-methylspiro[androsta-1,4-diene-17,2(3H)-furan]-3,3-dione

CAS: 1486466-31-2

Clobetasol propionate is an organic acid with a chemical structure that is stable in pharmaceutical preparations. It is used to treat inflammatory skin disorders such as psoriasis and atopic dermatitis. Clobetasol propionate is an impurity of clobetasol, which has been shown to be chemically stable in preparations. The clobetasol propionate compound has been found to be more potent than other topical corticosteroids for the treatment of plaque psoriasis and atopic dermatitis.

Formel: C₂₅H₃₀ClFO₄

Reinheit: Min. 95%

Molekulargewicht: 448.95 g/mol

Ref: 3D-FF103612