CAS 14875-96-8

Häm

Beschreibung:

Häm ist ein komplexes organisches Molekül, das eine entscheidende Rolle in verschiedenen biologischen Prozessen spielt, hauptsächlich als prosthetische Gruppe in Hämoproteinen wie Hämoglobin und Myoglobin. Es besteht aus einem Eisenion, das in einem Porphyrinring enthalten ist, einer zyklischen Struktur, die aus vier Pyrroluntereinheiten besteht, die durch Methinbrücken verbunden sind. Das Eisen in Häm kann in verschiedenen Oxidationszuständen existieren, was ihm ermöglicht, an Redoxreaktionen teilzunehmen und sich an Sauerstoff, Kohlenmonoxid und andere kleine Moleküle zu binden. Häm ist entscheidend für den Transport und die Speicherung von Sauerstoff in lebenden Organismen sowie für den Elektronentransfer in der Zellatmung. Seine Struktur ermöglicht die reversible Bindung von Sauerstoff, was es für den aeroben Stoffwechsel von entscheidender Bedeutung macht. Darüber hinaus ist Häm an verschiedenen enzymatischen Reaktionen beteiligt, einschließlich der von Cytochromen katalysierten, die für den Arzneimittelstoffwechsel und Entgiftungsprozesse wichtig sind. Die CAS-Nummer 14875-96-8 identifiziert spezifisch Häm und hebt seine Bedeutung in der Biochemie und Medizin hervor.

Formel: C₃₄H₃₀FeN₄O₄·2H

InChl: InChI=1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13?,27-14?,28-15?,29-14-,30-15-,31-16-,32-16?;

InChI Key: InChIKey=KABFMIBPWCXCRK-ADOXYXQCSA-L

SMILES: C(CC([O-])=O)C=1C=2[N-]3[Fe+2]45[N]6=C(C2)C(CCC([O-])=O)=C(C)C6=CC=7[N-]4C(C=C8[N]5=C(C=C3C1C)C(C=C)=C8C)=C(C=C)C7C.[H+]

Synonyme:

• 1,3,5,8-Tetramethyl-2,4-divinylporphine-6,7-dipropionic acid ferrous complex
• 21H,23H-Porphine, ferrate(2-) deriv.
• 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, iron complex
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N²¹,N²²,N²³,N²⁴]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, hydrogen (1:2), (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, hydrogen (1:2), (SP-4-2)-
• Ferroheme
• Ferroprotoporphyrin IX
• Hem Fe
• Heme
• Heme b
• Hydrogen [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]ferrate (heme)
• Iron protoporphyrin
• Iron protoporphyrin IX
• Iron(II) protoporphyrin IX
• Nsc 267100
• Protoheme
• Protoheme IX
• Protoporphyrin IX, iron deriv.
• Protoporphyrin, iron complex
• Reduced hematin
• [3,8,13,17-Tetramethyl-7,12-divinyl-21H,23H-porphine-2,8-dipropanoato(4-)-N21,N22,N23,N24]ferrate(2-) de dihydrogene (SP-4-2)
• [Dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]iron

Heme

CAS: 14875-96-8

Formel: C₃₄H₃₀FeN₄O₄

Reinheit: 97%

Farbe und Form: Solid

Molekulargewicht: 616.4873

Ref: IN-DA00AOIN

Ferroheme

CAS: 14875-96-8

Ferroheme

Reinheit: ≥95%

Molekulargewicht: 616.49g/mol

Ref: 54-BUP08076

Hematin (Fe(II) Protoporphyrin IX)

CAS: 14875-96-8

Formel: C₃₄H₃₂FeN₄O₄

Molekulargewicht: 616.50

Ref: 4Z-H-042001

Ferroheme

CAS: 14875-96-8

Ferroheme: iron-containing porphyrin in hemoglobin and other hemeproteins; colors tissues.

Formel: C₃₄H₃₂FeN₄O₄

Reinheit: 97.63%

Farbe und Form: Solid

Molekulargewicht: 616.49

Ref: TM-T8948

Ferroprotoporphyrin IX

CAS: 14875-96-8

Stability Light Sensitive
Applications Ferroprotoporphyrin IX is a metabolite formed during biosynthesis and is used to evaluate iron nutrition and metabolism. It is also an iron containing cofactor that is involved with a wide range of cellular functions including oxygen transport.
References Labbe, R.F., et. al.: Clin. Chem., 45, 146 (1999); Yuan, X., et al.: Proc. Natl. Acad. Sci. USA 113, E5144 (2016);

Formel: C₃₄H₃₂FeN₄O₄₂

Farbe und Form: Neat

Molekulargewicht: 616.49

Ref: TR-F307610

HEME

CAS: 14875-96-8

Heme is an iron-containing, non-protein molecule that is essential for life. Heme has a variety of biochemical properties and is important in the regulation of vital biological processes such as oxygen transport and metabolism of nitrogenous compounds. Heme can be found in two forms: heme A and heme B. The former consists of the protein globin combined with ferrous ion, while the latter is formed by the combination of protoporphyrin IX with ferrous ion. The synthesis of heme occurs through a series of reactions that involve oxidation and reduction reactions. The protoheme synthesis pathway results in the production of erythrocruorin, which is then converted to hemes A or B depending on its position in the globin protein chain. In addition to being an important cofactor for enzymes such as cytochrome c oxidase (complex IV), heme also functions as a substrate for heme oxygenase, which removes it from circulation to produce biliver

Formel: C₃₄H₃₂FeN₄O₄

Reinheit: Min. 95%

Molekulargewicht: 616.5 g/mol

Ref: 3D-PAA87596