CAS 149231-65-2
:N-acetyl-tyr-val-ala-asp 7-amido-4-*methylcumarine
Beschreibung:
N-Acetyl-Tyr-Val-Ala-Asp 7-Amido-4-Methylcoumarin, identifiziert durch seine CAS-Nummer 149231-65-2, ist eine synthetische Verbindung, die zur Klasse der Peptidderivate gehört. Diese Substanz weist eine Kombination von Aminosäuren auf, insbesondere N-Acetyltyrosin, Valin, Alanin und Asparaginsäure, die in einer spezifischen Sequenz miteinander verbunden sind. Das Vorhandensein der 7-Amido-4-Methylcoumarin-Gruppe deutet darauf hin, dass sie fluoreszierende Eigenschaften hat, was sie nützlich in biochemischen Assays und Forschungsanwendungen macht, insbesondere beim Studium der Enzymaktivität oder Proteininteraktionen. Die N-Acetylgruppe verbessert ihre Löslichkeit und Stabilität, während die Coumarin-Komponente als Reportergruppe in verschiedenen analytischen Techniken dienen kann. Insgesamt ist diese Verbindung durch ihre Peptidstruktur, potenzielle Bioaktivität und Nützlichkeit in fluoreszenzbasierten Anwendungen gekennzeichnet, was zu ihrer Relevanz in der biochemischen und pharmazeutischen Forschung beiträgt.
Formel:C33H39N5O10
Synonyme:- Ac-Yvad-Amc
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4 Produkte.
Ac-Tyr-Val-Ala-Asp-AMC
CAS:Ac-YVAD-AMC is a fluorogenic substrate for caspase-1 (ICE). It displayed a Km of 8.5 ± 0.5 µM for recombinant human caspase-1.Formel:C33H39N5O10Reinheit:99.3%Farbe und Form:White PowderMolekulargewicht:665.7Ac-Tyr-Val-Ala-Asp-AMC
CAS:Ac-Tyr-Val-Ala-Asp-AMC is a peptide that is used as a research tool to activate ion channels in cells and study the effects of ligands on these channels. It is also used in cell biology to study protein interactions, although it does not bind to any specific receptor. Ac-Tyr-Val-Ala-Asp-AMC belongs to the group of inhibitors and can be used for pharmacological purposes. The chemical structure of this peptide consists of a covalent bond between an amino acid and an acetylated form of a fluorescent molecule, which makes it suitable for use in fluorescence microscopy. Acetylated Tyr (Ac-Tyr) is one of the six amino acids found in proteins and has the ability to inhibit the activity of ion channels by binding to their external cavity. Acetylation at position 2 or 3 on Tyr can increase its affinity for calcium ion channels and affect their activation or deFormel:C33H39N5O10Reinheit:Min. 95%Molekulargewicht:665.69 g/molAc-Tyr-Val-Ala-Asp-AMC
CAS:Ac-Tyr-Val-Ala-Asp-AMC is a compound that has been shown to induce apoptotic cell death in MDA-MB-231 breast cancer cells. It inhibits the activity of proteases, which are enzymes that degrade proteins. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit serine proteases and granule neurons, which are proteins in the brain that regulate the production of atp levels. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit muscle cell proliferation. Acetylcholine (ACh) is a neurotransmitter responsible for signaling between nerve cells in the central nervous system and other parts of the body. Acetylcholine is synthesized by choline acetyltransferase (ChAT), an enzyme that breaks down acetylcholine into choline and acetate. Inhibition of ChAT leads to a decrease inFormel:C33H39N5O10Reinheit:Min. 95%Molekulargewicht:665.69 g/mol


