CAS 150238-87-2

H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2

Beschreibung:

Die chemische Substanz mit dem Namen "H-ALA-ARG-LEU-ASP-VAL-ALA-SER-GLU-PHE-ARG-LYS-LYS-TRP-ASN-LYS-TRP-ALA-LEU-SER-ARG-NH2" ist ein Peptid, das aus einer Sequenz von Aminosäuren besteht und speziell für verschiedene biochemische Anwendungen entwickelt wurde. Seine Struktur umfasst eine Kombination aus hydrophoben, polaren und geladenen Seitenketten, die zu seinen allgemeinen Eigenschaften wie Löslichkeit und Stabilität in wässrigen Umgebungen beitragen. Das Vorhandensein mehrerer Lysinreste deutet auf ein Potenzial für starke Wechselwirkungen mit negativ geladenen Molekülen hin, während die aromatischen Aminosäuren wie Phenylalanin und Tryptophan UV-Absorptionseigenschaften bieten können. Dieses Peptid kann biologische Aktivität zeigen und möglicherweise zelluläre Prozesse beeinflussen oder als Modell für das Studium von Proteinwechselwirkungen dienen. Die CAS-Nummer 150238-87-2 identifiziert diese Verbindung eindeutig in chemischen Datenbanken und erleichtert die Forschung und Anwendung in Bereichen wie Biochemie, Pharmakologie und Molekularbiologie. Ihre Synthese und Charakterisierung würden typischerweise Techniken wie die Hochleistungsflüssigkeitschromatographie (HPLC) und die Massenspektrometrie umfassen, um Reinheit und strukturelle Integrität zu bestätigen.

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Synonyme:

• H-Ala-Arg-Leu-Asp-Val-Ala-Ala-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2
• Arldvaaefrkkwnkwalsr-Nh2
• Arldvasefrkkwnkwalsr-Nh2
• Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-Nh2
• Pamp
• Pamp (1-20) Human
• Pamp Fragment 1-20 Human

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂-terminal 20 peptide (PAMP). The i.v. administration of PAMP produces a rapid and strong hypotensive effect in anesthetized rats. It has been suggested, that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Furthermore, it has been suggested that PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Reinheit: 97.2%

Farbe und Form: Whitish

Molekulargewicht: 2460.87

Ref: 01-4034490

Proadrenomedullin (1-20), human

CAS: 150238-87-2

Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 2460.84

Ref: TM-TP1490

PAMP (Human)

CAS: 150238-87-2

PAMP (human) is a peptide that binds to the G-protein coupled receptor, M3. It activates the ion channel and induces an influx of calcium ions into cells. This can lead to cell proliferation and differentiation, as well as increased blood flow in the brain. PAMP has been shown to inhibit ligand-induced activation of M3 receptors by competing with the natural ligands for binding sites on these receptors. It has also been shown to have high purity (>95%), and is currently under research for its use in various medical applications such as cancer therapy, pain management, and treatment of respiratory diseases.

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Reinheit: Min. 95%

Molekulargewicht: 2,460.8 g/mol

Ref: 3D-PAM-4291-V

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Molekulargewicht: 2,460.87 g/mol

Ref: 3D-PP51060

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

H-ARLDVASEFRKKWNKWALSR-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ARLDVASEFRKKWNKWALSR-NH2 is provided at greater that >95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ARLDVASEFRKKWNKWALSR-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ARLDVASEFRKKWNKWALSR-NH2 at the technical inquiry form on this page

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Reinheit: Min. 95%

Molekulargewicht: 2,460.87 g/mol

Ref: 3D-VAB-07852

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Custom research peptide; min purity 95%.

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Reinheit: Min. 95%

Molekulargewicht: 2,460.87 g/mol

Ref: 3D-PP17083

Proadrenomedullin (1-20) (human)

CAS: 150238-87-2

Proadrenomedullin (1-20) is a polypeptide that is found in human plasma. It is a member of the vasoactive intestinal peptide family and has been shown to be involved in the regulation of vascular tone, blood pressure, and blood vessel permeability. Proadrenomedullin (1-20) also inhibits the production of proinflammatory cytokines such as tumor necrosis factor-alpha, interleukin-6, and interleukin-8. This compound has been shown to have antiviral activity against HIV and herpes simplex virus type 1. Proadrenomedullin (1-20) also functions as a growth factor for tumor cells.

Formel: C₁₁₂H₁₇₈N₃₆O₂₇

Reinheit: Min. 95%

Molekulargewicht: 2,460.84 g/mol

Ref: 3D-FP109402