CAS 150322-43-3

Prasugrel

Beschreibung:

Prasugrel ist ein antiplättchenmedikament, das hauptsächlich zur Verringerung des Risikos von kardiovaskulären Ereignissen bei Patienten mit akutem Koronarsyndrom, die sich einer perkutanen koronaren Intervention unterziehen, eingesetzt wird. Es handelt sich um ein Thienopyridin-Derivat, das durch irreversible Hemmung des P2Y12-Rezeptors auf Thrombozyten wirkt und somit die Thrombozytenaggregation verhindert. Prasugrel zeichnet sich durch seine schnelle Absorption und Umwandlung in ein aktives Metabolit aus, was seine Wirksamkeit im Vergleich zu anderen antiplättchenmedikamenten erhöht. Die chemische Formel von Prasugrel lautet C20H20FNO3S, und es hat ein Molekulargewicht von etwa 343,44 g/mol. Der Stoff wird typischerweise in Form eines Prodrugs verabreicht, das eine metabolische Aktivierung erfordert, um seine therapeutischen Wirkungen zu entfalten. Prasugrel ist bekannt für seine relativ vorhersehbare Pharmakokinetik und Pharmakodynamik, was es zu einer bevorzugten Wahl in bestimmten klinischen Kontexten macht. Es ist jedoch mit einem erhöhten Risiko für Blutungen verbunden, was eine sorgfältige Auswahl und Überwachung der Patienten erfordert. Sein Sicherheits- und Wirksamkeitsprofil wurde durch verschiedene klinische Studien etabliert, was zu seiner Akzeptanz in der klinischen Praxis zur Behandlung von thrombotischen kardiovaskulären Ereignissen beigetragen hat.

Formel: C₂₀H₂₀FNO₃S

InChl: InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3

InChI Key: InChIKey=DTGLZDAWLRGWQN-UHFFFAOYSA-N

SMILES: C(C(=O)C1CC1)(N2CC3=C(CC2)SC(OC(C)=O)=C3)C4=C(F)C=CC=C4

Synonyme:

• 2-Acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine
• 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone
• 5-[2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl]-4,5,6,7-
• Acetic acid 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl ester
• Cs 747
• Effient free base
• Ethanone, 2-(2-(acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)-
• Ly 640315
• Prasugrel Base
• Prasugrel [INN]
• Tetrahydrothieno[3,2-C]Pyridin-2-Yl Acetate
• Thieno[3,2-c]pyridine, ethanone deriv.
• [5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxo-ethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• Prasugrel
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-

Prasugrel

CAS: 150322-43-3

Formel: C₂₀H₂₀FNO₃S

Reinheit: >98.0%(T)(HPLC)

Farbe und Form: Light yellow to Yellow to Orange powder to crystal

Molekulargewicht: 373.44

Ref: 3B-P2040

2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone

CAS: 150322-43-3

Formel: C₂₀H₂₀FNO₃S

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 373.4411

Ref: IN-DA001MIM

Prasugrel

CAS: 150322-43-3

Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME;

Formel: C₂₀H₂₀FNO₃S

Reinheit: 99.62% - 99.82%

Farbe und Form: White Solid

Molekulargewicht: 373.44

Ref: TM-T0230

Prasugrel

CAS: 150322-43-3

Formel: C₂₀H₂₀FNO₃S

Farbe und Form: Off-White Solid

Molekulargewicht: 373.44

Ref: 4Z-P-391

Prasugrel

CAS: 150322-43-3

Prasugrel

Reinheit: 99%

Molekulargewicht: 373.44g/mol

Ref: 54-PC109116

Prasugrel

CAS: 150322-43-3

Prasugrel

Reinheit: ≥98%

Molekulargewicht: 373.44g/mol

Ref: 54-BUP15051

Prasugrel

CAS: 150322-43-3

Formel: C₂₀H₂₀FNO₃S

Molekulargewicht: 373.44

Ref: 7W-GP4257

(±)-Prasugrel-d3 (acetate-d3)

CAS: 1127253-02-4, 150322-43-3

Reinheit: 99 atom % D

Farbe und Form: Off White Solid

Molekulargewicht: 376.46

Ref: 3U-D7536

Prasugrel

CAS: 150322-43-3

Reinheit: 95.0%

Farbe und Form: Solid

Molekulargewicht: 373.44000244140625

Ref: 10-F390330

Prasugrel - Bio-X ™

CAS: 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties. 
Prasugrel is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formel: C₂₀H₂₀FNO₃S

Reinheit: (%) Min. 95%

Molekulargewicht: 373.44 g/mol

Ref: 3D-BP164290

Prasugrel

CAS: 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties.

Formel: C₂₀H₂₀FNO₃S

Reinheit: Min. 95%

Farbe und Form: Powder

Molekulargewicht: 373.44 g/mol

Ref: 3D-FP10815

Prasugrel

CAS: 150322-43-3

Applications Prasugrel is a platelet inhibitor that reduces aggregation of platelets by being a P2Y12(ADP receptor) inhibitor.

Formel: C₂₀H₂₀FNO₃S

Farbe und Form: Neat

Molekulargewicht: 373.44

Ref: TR-P701188