
CAS 153437-78-6
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5 Produkte.
O-Desmorpholinopropyl-O-methyl-gefitinib
CAS:Kontrolliertes ProduktApplications O-Desmorpholinopropyl-O-methyl-gefitinib is a anilinoquinazoline derivative of which acts as an inhibitor of tyrosine kinases and found to be allosteric inhibitors of the enzyme frutose 1,6-bisphosphatase. It serves as a lead to further drug design.
References Wright, S. W., Bioorganic & Medicinal Chemistry Letters, 11, 17-21, (2000)Formel:C16H13ClFN3O2Farbe und Form:White To Off-WhiteMolekulargewicht:333.74o-Desmorpholinopropyl-o-methyl-gefitinib
CAS:O-Desmorpholinopropyl-o-methyl-gefitinib is a cytotoxic drug that activates cancer cells. This compound has been shown to be reactive with colon cancer cells, inducing apoptosis and inhibiting the growth of cancer cells in vitro. O-Desmorpholinopropyl-o-methyl-gefitinib induces cell death in colon cancer cells by activating caspase 9 and caspase 3, which are enzymes that cleave proteins that activate other downstream effectors of apoptosis. O-Desmorpholinopropyl-o-methyl-gefitinib also inhibits the proliferation of human colorectal cancer cells (HCT116) and SW620 colon cancer cells.Formel:C16H13ClFN3O2Reinheit:Min. 95%Molekulargewicht:333.74 g/mol




