CAS 1546918-95-9
:1-epi-Darunavir
CAS:Kontrolliertes ProduktApplications Stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.
References Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),Formel:C27H37N3O7SFarbe und Form:White To Off-WhiteMolekulargewicht:547.66(2R)-Darunavir-d9
CAS:Kontrolliertes ProduktApplications Stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. This is a labeled analog. It is a COVID19-related research product.
References Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),Formel:C27H28D9N3O7SFarbe und Form:NeatMolekulargewicht:547.661-Epi-darunavir
CAS:1-Epi-darunavir is a potent HIV protease inhibitor that blocks the cleavage of polyproteins that are necessary for the assembly and release of new viruses. It is an epimer of darunavir and has been shown to be more potent than its parent compound. 1-Epi-darunavir binds to the active site of HIV protease and prevents the formation of a complex between the enzyme and its substrate, leading to inhibition of HIV replication. This drug also inhibits ion channels, including calcium channels, potassium channels, sodium channels, and chloride channels. 1-Epi-darunavir has been shown to inhibit ligand binding to receptors in cell culture, such as peptides or antibodies.
Formel:C27H37N3O7SReinheit:Min. 95%Molekulargewicht:547.7 g/mol
