CAS 163712-68-3

2Z-Nalfurafine

Kontrolliertes Produkt

CAS: 163712-68-3

Applications 2Z-Nalfurafine is a geometric isomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)

Formel: C₂₈H₃₂N₂O₅

Farbe und Form: Neat

Molekulargewicht: 476.56

Ref: TR-N255610

2Z-Nalfurafine-d3

Kontrolliertes Produkt

CAS: 163712-68-3

Formel: C₂₈H₂₉D₃N₂O₅

Farbe und Form: Neat

Molekulargewicht: 479.58

Ref: TR-N255612

2Z-Nalfurafine (1 mg/ml in Acetonitrile)

Kontrolliertes Produkt

CAS: 163712-68-3

Formel: C₂₈H₃₂N₂O₅

Farbe und Form: Single Solution

Molekulargewicht: 476.56

Ref: TR-KIT6350