CAS 167466-66-2

(S)-2-(Acetylthio)-propanoic Acid

Kontrolliertes Produkt

CAS: 167466-66-2

Applications (S)-2-(Acetylthio)-propanoic Acid is an intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).
References Kapilashrami, K., et al.: J. Biol. Chem., 288, 6045 (2013); Paneerselvam, V., et al.: J. Pharm. Res., 4, 4618 (2011); Katane, M., et al.: Biochimie, 92, 1371 (2010)

Formel: C₅H₈O₃S

Farbe und Form: Neat

Molekulargewicht: 148.18

Ref: TR-A189223