CAS 1708948-28-0

NA-17

CAS: 1708948-28-0

NA-17 is a naphthalimide compound with antitumor activity and exhibits lower toxicity to normal cells such as HL-7702 and WI-38. It demonstrates p53-dependent inhibition selectivity in various NSCLC cells, inducing the accumulation of active p53 in the mitochondria and nuclei of these cells. NA-17 causes cell cycle arrest in the G1 phase and promotes apoptosis and cell death.

Formel: C₂₆H₂₇N₃O₄

Farbe und Form: Solid

Molekulargewicht: 445.51

Ref: TM-T204205