CAS 1784-03-8

L-Arginin, N2-[(4-methylphenyl)sulfonyl]-, Methylester, Hydrochlorid (1:1)

Beschreibung:

L-Arginin, N2-[(4-methylphenyl)sulfonyl]-, Methylester, Hydrochlorid (1:1) ist eine chemische Verbindung, die eine Kombination aus einer Aminosäure, L-Arginin, und einer Sulfonylgruppe, die an ein Methylphenyl-Moiety gebunden ist, aufweist. Diese Verbindung zeichnet sich durch ihre basische Aminosäurestruktur aus, die eine Guanidiniumgruppe umfasst, die zu ihrer Rolle in verschiedenen biologischen Prozessen beiträgt, wie z.B. der Proteinsynthese und der Produktion von Stickstoffmonoxid. Das Vorhandensein des Methylesters weist darauf hin, dass es sich um ein Derivat von L-Arginin handelt, das seine Löslichkeit und Bioverfügbarkeit verbessern kann. Die Hydrochloridform deutet darauf hin, dass es sich um ein Salz handelt, das typischerweise die Stabilität und Handhabungseigenschaften verbessert. Diese Verbindung kann verschiedene pharmakologische Aktivitäten aufweisen, einschließlich potenzieller Rollen in der kardiovaskulären Gesundheit und der Immunfunktion. Ihre Sulfonylgruppe kann auch ihre Reaktivität und Wechselwirkung mit biologischen Zielen beeinflussen. Insgesamt ist L-Arginin, N2-[(4-Methylphenyl)sulfonyl]-, Methylester, Hydrochlorid sowohl für die biochemische Forschung als auch für potenzielle therapeutische Anwendungen von Interesse.

Formel: C₁₄H₂₂N₄O₄S·ClH

InChl: InChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1

InChI Key: InChIKey=JIQFFACVQXXHMY-YDALLXLXSA-N

SMILES: S(N[C@@H](CCCNC(=N)N)C(OC)=O)(=O)(=O)C1=CC=C(C)C=C1.Cl

Synonyme:

• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride
• Arginine, N²-(p-tolylsulfonyl)-, methyl ester, monohydrochloride, <span class="text-smallcaps">L</span>-
• N-alpha-Toluenesulfonylarginine methyl ester hydrochloride
• N-alpha-Tosyl-L-arginine methyl ester hydrochloride
• N-p-Tosyl-L-arginine methyl ester hydrochloride
• N-α-p-Tosyl-L-arginine methyl ester hydrochloride
• N^α-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Nalpha-(4-Toluenesulfonyl)-L-Arginine Methyl Ester Hydrochloride
• Tame
• Tos-Arg-OMe . HCl
• Tos-Arg-OMe・HCl
• Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Tosylarginine methyl ester hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]-L-ornithinate hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]ornithinate hydrochloride
• na-P-tosyl-L-arginine methyl*ester hydrochloride
• α-N-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• α-N-Tosyl-L-arginine methyl ester hydrochloride
• Nα-Tosyl-L-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride

Nα-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Formel: C₁₄H₂₂N₄O₄S·HCl

Reinheit: >98.0%(T)

Farbe und Form: White to Almost white powder to crystal

Molekulargewicht: 378.87

Ref: 3B-T0330

Tos-Arg-OMe · HCl

CAS: 1784-03-8

A good substrate for trypsin, thrombin, and urokinase as well as for plasma and glandular kallikreins. By competing for the arginine-binding site in the reactive center of proteases, L-TAME is also able to act as a reversible inhibitor. It suppresses, e.g., the TNF secretion of human leukocytes which is evidently dependent upon the action of serine proteases.

Formel: C₁₄H₂₂N₄O₄S·HCl

Reinheit: > 99%

Farbe und Form: White Powder

Molekulargewicht: 378.88

Ref: 01-4002251

L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)

CAS: 1784-03-8

Formel: C₁₄H₂₃ClN₄O₄S

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 378.8748

Ref: IN-DA0025ZQ

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.

Formel: C₁₄H₂₃ClN₄O₄S

Reinheit: 99.11% - 99.21%

Farbe und Form: White Fine Crystalline Powder

Molekulargewicht: 378.87

Ref: TM-T1731

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride

Reinheit: ≥95%

Molekulargewicht: 378.87g/mol

Ref: 54-BUP17017

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

Reinheit: 98%

Molekulargewicht: 378.87g/mol

Ref: 54-OR1014507

TAME Hydrochloride

CAS: 1784-03-8

Formel: C₁₄H₂₂N₄O₄S·HCl

Reinheit: ≥ 98.0%

Farbe und Form: White to almost white powder

Molekulargewicht: 378.87

Ref: 7W-GM4942

N-α-Tosyl-L-arginine methyl ester hydrochloride

CAS: 1784-03-8

N-alpha-Tosyl-L-arginine methyl ester hydrochloride is a potent inhibitor of the serine protease leishmania. It inhibits the enzyme by binding to its active site and interfering with the enzymatic reaction. This drug has been shown to be effective in treating bladder infections caused by leishmania, although it can cause a decrease in responsiveness in an animal model. N-alpha-Tosyl-L-arginine methyl ester hydrochloride also has anti-HIV activities, which may be due to its ability to inhibit HIV replication. The drug is most likely absorbed through the apical surface of the bladder epithelium and then diffuses into the extracellular space, where it inhibits key enzymes involved in viral replication.

Formel: C₁₄H₂₂N₄O₄S·HCl

Reinheit: Min. 95%

Farbe und Form: White Off-White Powder

Molekulargewicht: 378.88 g/mol

Ref: 3D-FT55915

TAME hydrochloride

CAS: 1784-03-8

Reinheit: 98%

Molekulargewicht: 378.87

Ref: 10-M03112

N-4-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Applications N-4-Tosyl-L-arginine Methyl Ester Hydrochloride acts as a synthetic substrate of serine proteases and thus is used to determine serine proteases from diverse organic sources.
References Hummel, B. et al.: Can. J. Biochem. Physiol., 37, 1393 (1959); Matsuda, Y. et al.: J. Biochem. 80, 671 (1976);

Formel: C₁₄H₂₃ClN₄O₄S

Farbe und Form: Neat

Molekulargewicht: 378.87

Ref: TR-T570000

TAME hydrochloride

CAS: 1784-03-8

Tos-Arg-OMe • HCl is a peptide that has been shown to modulate the responsiveness of cells to sodium channels. Tos-Arg-OMe • HCl may also be useful as an anti-cancer drug, as it inhibits cancer cell growth and induces apoptosis. This peptide has been shown to be an effective treatment for HIV infection by inhibiting viral replication. It also reduces inflammation and prevents the development of other opportunistic infections in animal models.

Formel: C₁₄H₂₂N₄O₄S·ClH

Reinheit: Min. 95%

Molekulargewicht: 378.87 g/mol

Ref: 3D-STR-3003