CAS 1788872-06-9

5-Chloro-2-fluoro-4-[[(tetrahydro-1H-pyrrolizin-7a(5H)-yl)methyl]amino]-N-2-thiazolylbenzenesulfonamide

CAS: 1788872-06-9

5-Chloro-2-fluoro-4-[[(tetrahydro-1H-pyrrolizin-7a(5H)-yl)methyl]amino]-N-2-thiazolylbenzenesulfonamide is a potent inhibitor of voltage gated sodium channels. It has been shown to inhibit the activation of these channels, which are involved in the transmission of nerve impulses. This leads to an increase in neuronal excitability and also has an effect on cardiac function. 5CFB is a high purity compound, with >95% purity by HPLC and NMR measurements.

Formel: C₁₇H₂₀ClFN₄O₂S₂

Reinheit: Min. 95%

Molekulargewicht: 431 g/mol

Ref: 3D-NWC87206

Nav1.7-IN-3

CAS: 1788872-06-9

Nav1.7-IN-3 is a selective and orally bioavailable inhibitor of voltage-gated sodium channel Nav1.7(IC50 of 8 nM).

Formel: C₁₇H₂₀ClFN₄O₂S₂

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 430.95

Ref: TM-T12183