CAS 1811-31-0

GalNAc

Beschreibung:

GalNAc, oder N-Acetylgalactosamin, ist ein Aminozucker und ein Derivat von Galactose. Es ist gekennzeichnet durch das Vorhandensein einer Acetylgruppe, die an die Aminogruppe des Galactosemoleküls gebunden ist. Diese Verbindung spielt eine entscheidende Rolle in verschiedenen biologischen Prozessen, insbesondere bei der Synthese von Glykoproteinen und Glykolipiden, wo sie als Baustein für komplexe Kohlenhydrate dient. GalNAc ist auch an Zellsignalisierungs- und Erkennungsprozessen beteiligt, die zelluläre Interaktionen und Immunantworten beeinflussen. Es kommt typischerweise in Form eines weißen kristallinen Pulvers vor und ist in Wasser löslich. Die Verbindung ist ungiftig und wird in verschiedenen biochemischen Anwendungen eingesetzt, einschließlich Forschung und therapeutischer Entwicklung. Ihre strukturellen Eigenschaften ermöglichen es, an verschiedenen enzymatischen Reaktionen teilzunehmen, was sie in der Glycobiologie bedeutend macht. Insgesamt ist GalNAc ein wesentlicher Bestandteil der Biochemie lebender Organismen und trägt zur Komplexität und Funktionalität zellulärer Strukturen bei.

Formel: C₈H₁₅NO₆

InChl: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8-/m0/s1

InChI Key: InChIKey=MBLBDJOUHNCFQT-OSMVPFSASA-N

SMILES: [C@H]([C@H]([C@H]([C@@H](CO)O)O)O)(NC(C)=O)C=O

Synonyme:

• 2-(Acetylamino)-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-(Acetylamino)-2-deoxy-D-galactose
• 2-Acetamido-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-Acetamido-2-deoxy-D-galactose
• 2-Deoxy-2-acetamido-<span class="text-smallcaps">D</span>-galactose
• 2-Deoxy-2-acetamido-D-galactose
• 2-N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• 2-N-Acetyl-D-galactosamine
• <span class="text-smallcaps">D</span>-Galactose, 2-(acetylamino)-2-deoxy-
• <span class="text-smallcaps">D</span>-N-Acetylgalactosamine
• D-N-Acetylgalactosamine
• GalNAc
• Galactosamine, N-acetyl-, <span class="text-smallcaps">D</span>-
• Galactosamine, N-acetyl-, D-
• Galactose, 2-acetamido-2-deoxy-, <span class="text-smallcaps">D</span>-
• Galactose, 2-acetamido-2-deoxy-, D-
• N-Acetyl-2-amino-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• N-Acetyl-2-amino-2-deoxy-D-galactose
• N-Acetyl-2-amino-2-deoxygalactose
• N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• N-Acetyl-D-galactosamine
• N-Acetyl-β-D-galaktosamin
• N-Acetylchondrosamine
• N-Acetylgalactosamine
• N-acetil-β-D-galactosamina
• N-acetyl-β-D-galactosamine

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine is the initial O-linked sugar to many serine and threonine residues in protein glycosylation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The o

Formel: C₈H₁₅NO₆

Farbe und Form: Crystals or crystalline powder, White

Molekulargewicht: 221.21

Ref: 02-J66095

D-Galactose, 2-(acetylamino)-2-deoxy-

CAS: 1811-31-0

Formel: C₈H₁₅NO₆

Reinheit: 80%

Farbe und Form: Solid

Molekulargewicht: 221.2078

Ref: IN-DA0022OP

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Formel: C₈H₁₅NO₆

Reinheit: 95%

Farbe und Form: white solid

Molekulargewicht: 221.21g/mol

Ref: 54-OR7700T

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine

Reinheit: ≥98%

Molekulargewicht: 221.21g/mol

Ref: 54-BUP18207

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Formel: C₈H₁₅NO₆

Reinheit: 97%

Farbe und Form: white to off-white solid

Molekulargewicht: 221.21g/mol

Ref: 54-BIM1065

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).

Formel: C₈H₁₅NO₆

Reinheit: 99.79% - 99.91%

Farbe und Form: White Crystalline Powder

Molekulargewicht: 221.21

Ref: TM-T4708

N-Acetyl-D-galactosamine

Kontrolliertes Produkt

CAS: 1811-31-0

Applications N-Acetyl-D-galactosamine (cas# 1811-31-0) is a compound useful in organic synthesis.
References Nakajima, M., et al.: App. Microbiol. Biotechnol., 83, 109 (2009), Singh, S., et al.: Mol. Immunol., 46, 1240 (2009),

Formel: C₈H₁₅NO₆

Farbe und Form: Neat

Molekulargewicht: 221.2078

Ref: TR-A177000

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-Acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of acetylgalactosamine residues attached to the IgA O-linked glycans of Crohn'sdisease patients is significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohn's disease (Inoue, 2012).

Formel: C₈H₁₅NO₆

Reinheit: Min. 98%

Farbe und Form: White Powder

Molekulargewicht: 221.21 g/mol

Ref: 3D-MA04390

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-acetyl D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of GalNAc residues attached to the IgA O-linked glycans of Crohns Disease patients was significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohns Disease (Inoue, 2012).

Formel: C₈H₁₅NO₆

Reinheit: Min. 99.0 Area-%

Molekulargewicht: 221.21 g/mol

Ref: 3D-A-1170

N-((2R,3R,4R,5R)-3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)acetamide

CAS: 1811-31-0

Formel: C₈H₁₅NO₆

Reinheit: 80%

Farbe und Form: Solid, Crystalline or Powder

Molekulargewicht: 221.209

Ref: 10-F239286

N-Acetyl-D-galactosamine, plant-based

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose. It forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides.This N-Acetyl-D-galactosamine product (MA184543) is plant-based and produced synthetically from Arabic gum.GalNAc clusters and derivatives, typically composed of three (or more) GalNAc moieties arranged in a specific spatial configuration, are a powerful tool for targeted delivery of nucleic acid therapeutics, specifically in liver targeted therapies. These multivalent ligands effectively bind and internalize via the asialoglycoprotein receptor (ASGPR) expressed on the surface of hepatocytes.

Formel: C₈H₁₅NO₆

Reinheit: Min. 97 Area-%

Molekulargewicht: 221.21 g/mol

Ref: 3D-MA184543