
CAS 1816331-66-4
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3 Produkte.
GSK864
CAS:<p>GSK864 is a small molecule that inhibits pd-l1, a protein that is important for the development of cancer. GSK864 has been shown to inhibit the production of histone H3, which is an essential component of the nucleosome and plays a role in DNA replication and transcription. GSK864 also promotes demethylation and inhibits 2-hydroxyglutarate (HG), which is involved in cellular metabolism and produces energy. This drug also increases production of secretome, which contains proteins that are involved in tumor growth.</p>Formel:C30H31FN6O4Reinheit:Min. 95%Molekulargewicht:558.6 g/molGSK864
CAS:GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).Formel:C30H31FN6O4Reinheit:97.07%Farbe und Form:SolidMolekulargewicht:558.6


