CAS 189035-07-2

(11b,17b)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one

Kontrolliertes Produkt

CAS: 189035-07-2

Applications (11β,17β)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one is a glucocorticoid receptor (GR) antagonists.
References Verdouw, P. M., et al.: Pharmacol. Biochem. Behav., 154, 11-19 (2017); Reynolds, A. R., et al.: Drug Alcohol. Dep., 154, 100-104 (2015)

Formel: C₂₈H₃₀O₄

Farbe und Form: Neat

Molekulargewicht: 430.54

Ref: TR-B198850

(11Beta,17Beta)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one

CAS: 189035-07-2

17-Hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one is a synthetic peptide that is a potent inhibitor of the protein interactions of the follicle stimulating hormone receptor (FSHR). The molecular structure of 17OHPED is similar to that of GnRH, and it is an agonist at the FSHR. 17OHPED has been shown to activate LHRH release in vitro and in vivo with large potency. It has also been shown to be a highly potent inhibitor of FSHR binding to its ligand, FSH. This compound can be used as a research tool for studying the interaction between proteins.

Formel: C₂₈H₃₀O₄

Reinheit: Min. 95%

Molekulargewicht: 430.50 g/mol

Ref: 3D-PHA03507

Org-34517

CAS: 189035-07-2

Org-34517, a glucocorticoid receptor (GR) antagonist, is used potentially for the treatment of depression.

Formel: C₂₈H₃₀O₄

Reinheit: 98%

Farbe und Form: Solid

Molekulargewicht: 430.54

Ref: TM-T28265