CAS 18942-49-9
:N-tert-Butoxycarbonyl-D-phenylalanin
Beschreibung:
N-tert-Butoxycarbonyl-D-phenylalanin, allgemein bekannt als Boc-D-Phenylalanin, ist ein Aminosäurederivat, das durch das Vorhandensein einer tert-butyloxycarbonyl (Boc) Schutzgruppe gekennzeichnet ist, die an die Aminogruppe von D-Phenylalanin gebunden ist. Diese Verbindung wird typischerweise in der Peptidsynthese als Schutzgruppe verwendet, die die selektive Modifikation von Aminosäuren erleichtert, ohne andere funktionelle Gruppen zu stören. Es handelt sich um einen weißen bis cremefarbenen Feststoff, der in organischen Lösungsmitteln wie Dichlormethan und Dimethylformamid löslich ist, jedoch im Allgemeinen unlöslich in Wasser. Die Boc-Gruppe ist bekannt für ihre Stabilität unter basischen Bedingungen und kann unter sauren Bedingungen leicht entfernt werden, was sie zu einem wertvollen Werkzeug in der organischen Synthese macht. Das Vorhandensein der Phenylgruppe trägt zu den hydrophoben Eigenschaften der Verbindung bei und beeinflusst deren Wechselwirkungen in biologischen Systemen. Als chirale Moleküle existiert es in zwei enantiomeren Formen, wobei die D-Form in verschiedenen biochemischen Anwendungen verwendet wird. Insgesamt ist Boc-D-Phenylalanin im Bereich der medizinischen Chemie und der Peptidforschung von Bedeutung.
Formel:C14H19NO4
InChl:InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m1/s1
InChI Key:InChIKey=ZYJPUMXJBDHSIF-LLVKDONJSA-N
SMILES:[C@H](CC1=CC=CC=C1)(NC(OC(C)(C)C)=O)C(O)=O
Synonyme:- (2R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
- (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
- (2R)-2-[(tert-Butoxycarbonyl)amino]-3-phenylpropionic acid
- (2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate
- (2R)-2-[[(tert-Butoxy)carbonyl]amino]-3-phenylpropanoic acid
- (R)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropionic acid
- (R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
- (R)-N-(tert-Butoxycarbonyl)phenylalanine
- <span class="text-smallcaps">D</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
- Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, <span class="text-smallcaps">D</span>-
- BOC-<span class="text-smallcaps">D</span>-phenylalanine
- Boc-D-Phe-OH
- N-(tert-Butoxycarbonyl)-D-phenylalanine
- N-BOC-<span class="text-smallcaps">D</span>-phenylalanine
- N-Boc-D-phenylalanine
- N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">D</span>-phenylalanine
- N-tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- N-tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butoxycarbonyl-D-phenylalanine
- Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, D-
- D-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
- Weitere Synonyme anzeigen
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13 Produkte.
N-(tert-Butoxycarbonyl)-D-phenylalanine
CAS:Formel:C14H19NO4Reinheit:>98.0%(T)Farbe und Form:White to Almost white powder to crystalMolekulargewicht:265.31N-Boc-D-phenylalanine, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formel:C14H19NO4Reinheit:98%Farbe und Form:Crystals or powder or crystalline powder, WhiteMolekulargewicht:265.31Boc-D-Phe-OH
CAS:<p>Bachem ID: 4000781.</p>Formel:C14H19NO4Reinheit:> 99%Farbe und Form:WhiteMolekulargewicht:265.31Boc-D-phenylalanine
CAS:<p>Boc-D-phenylalanine</p>Formel:C14H19NO4Reinheit:98%Farbe und Form: white to off-white powderMolekulargewicht:265.30g/molBoc-D-Phe-OH
CAS:<p>Boc-D-Phe-OH is an antimicrobial peptide that is a small molecule with a molecular weight of 254.8. It has been shown to have anti-tumor activity, and can be used as an alternative to conventional chemotherapeutic drugs in the treatment of cancer. Boc-D-Phe-OH binds to the hydrophobic region on the surface of cells and disrupts the cell's membrane, causing cell death by apoptosis. This peptide also shows antibacterial activity against gramicidin S, which is a Gram-positive antibiotic that belongs to the polymyxins class. The antibacterial activity of this peptide may be due to its ability to bind to divalent cations such as calcium ions and magnesium ions. Boc-D-Phe-OH has been synthesized using a method that is both efficient and rapid (less than 12 hours). It has also been shown that this peptide does not show any</p>Formel:C14H19NO4Reinheit:Min. 95%Molekulargewicht:265.3 g/molBoc-D-Phe-OH
CAS:<p>M03311 - Boc-D-Phe-OH</p>Formel:C14H19NO4Reinheit:98%Farbe und Form:Solid, Crystalline Powder or PowderMolekulargewicht:265.309N-Boc-D-phenylalanine
CAS:<p>D-Phenylalanine is a molecule that is used in the synthesis of peptidomimetics. It has been shown to have a high efficiency method in the synthesis of N-Boc-D-phenylalanine, which can be used as a glycosidic bond precursor. This chemical has been shown to have anti-tumor properties and it may be useful in binding experiments with ferrocene. The compound can also form hydrogen bonds with acids, such as the acid catalyst found in the digestive system.</p>Formel:C14H19NO4Reinheit:Min. 95%Farbe und Form:PowderMolekulargewicht:265.31 g/molBOC-D-Phenylalanine extrapure, 99%
CAS:Formel:C14H19NO4Reinheit:min. 99%Farbe und Form:White, PowderMolekulargewicht:265.30Boc-D-Phenylalanine
CAS:Kontrolliertes Produkt<p>Applications Boc-D-Phenylalanine is used in the synthesis of benzo[de][1,7]napthyridinones as PARP1 inhibitors. Also it is an important reagent in the preparation of proline-containing, β-turn mimetic cycle tetrapeptides.<br>References Ye, Na. et al.: J. Med. Chem., 56, 2885 (2013); Chouhan, G. et al.: Org. Lett., 15, 1206 (2013);<br></p>Formel:C14H19NO4Farbe und Form:NeatMolekulargewicht:265.3
